pediatric-ai-scribe-v3/public/js/calculators.js

// ============================================================
// CALCULATORS.JS — Pediatric clinical calculators
// ============================================================

(function() {
  var _inited = false;
  document.addEventListener('tabChanged', function(e) {
    if (e.detail.tab !== 'calculators' || _inited) return;
    _inited = true;
    initCalculators();
  });

  // ── Flexible age parser ─────────────────────────────────────────────
  // Accepts: "3y", "3 years", "29m", "29 months", "2y5m", "2 years 5 months",
  //          "15d", "15 days", "3y 2m 10d", "36" (months), "3.5 years", etc.
  // Returns age in months (may be fractional), or null if unparseable.
  function parseAgeMonths(input) {
    if (input == null) return null;
    var s = String(input).toLowerCase().trim();
    if (!s) return null;
    // Plain number with no unit: if >= 24 assume years, else months. Matches
    // common shorthand ("36" for 3y, "6" for 6 months).
    if (/^[\d.]+$/.test(s)) {
      var n = parseFloat(s);
      if (isNaN(n)) return null;
      return n >= 24 ? n : n; // keep as months; user can add unit if they meant years
    }
    var total = 0;
    var matched = false;
    // Use (?![a-z]) instead of \b so "2y5m" terminates "y" correctly.
    // Order matters: longest-first alternations (years before yrs before y, etc.).
    var my = s.match(/([\d.]+)\s*(?:years|year|yrs|yr|y)(?![a-z])/);
    if (my) { total += parseFloat(my[1]) * 12; matched = true; }
    var mm = s.match(/([\d.]+)\s*(?:months|month|mos|mo|m)(?![a-z])/);
    if (mm) { total += parseFloat(mm[1]); matched = true; }
    var mw = s.match(/([\d.]+)\s*(?:weeks|week|wks|wk|w)(?![a-z])/);
    if (mw) { total += parseFloat(mw[1]) * 7 / 30.4375; matched = true; }
    var md = s.match(/([\d.]+)\s*(?:days|day|d)(?![a-z])/);
    if (md) { total += parseFloat(md[1]) / 30.4375; matched = true; }
    return matched ? total : null;
  }

  function formatParsedAge(months) {
    if (months < 1) {
      var d = Math.round(months * 30.4375);
      return '= ' + d + ' day' + (d === 1 ? '' : 's') + ' (' + months.toFixed(2) + ' mo)';
    }
    if (months < 24) {
      return '= ' + (Math.round(months * 10) / 10) + ' months';
    }
    var yr = Math.floor(months / 12);
    var mo = Math.round(months - yr * 12);
    if (mo === 12) { yr += 1; mo = 0; }
    return '= ' + yr + ' yr' + (mo ? ' ' + mo + ' mo' : '') + ' (' + Math.round(months) + ' mo total)';
  }
  // Expose for debugging / other modules
  window._parseAgeMonths = parseAgeMonths;

  function initCalculators() {
    // ── Top-level pill navigation (scoped to .calc-nav-pill only) ──
    document.querySelectorAll('.calc-nav-pill').forEach(function(pill) {
      pill.addEventListener('click', function() {
        document.querySelectorAll('.calc-nav-pill').forEach(function(p) { p.classList.remove('active'); });
        document.querySelectorAll('.calc-panel').forEach(function(p) { p.classList.add('hidden'); });
        pill.classList.add('active');
        var panel = document.getElementById('calc-' + pill.dataset.calc);
        if (panel) panel.classList.remove('hidden');
      });
    });

    // ═══════════════════════════════════════════════════════════
    // BP PERCENTILE — BCM/Rosner Quantile Spline Regression
    // AAP 2017 classification with exact percentile computation
    // ═══════════════════════════════════════════════════════════

    // Height LMS parameters (218 entries, index 0 = month 24 / age 2y, index 217 = month 241)
    var _htLMS_F_L=[1.07244896,1.051272912,1.041951175,1.012592236,0.970541909,0.921129988,0.868221392,0.81454413,0.761957977,0.711660228,0.664323379,0.620285102,0.57955631,0.54198094,0.511429832,0.482799937,0.455521041,0.429150288,0.403351725,0.377878239,0.352555862,0.327270297,0.301955463,0.276583851,0.251158446,0.225705996,0.20027145,0.174913356,0.149700081,0.12470671,0.100012514,0.075698881,0.051847635,0.02853967,0.005853853,-0.016133871,-0.037351181,-0.057729947,-0.077206672,-0.09572283,-0.113225128,-0.129665689,-0.145002179,-0.159197885,-0.172221748,-0.184048358,-0.194660215,-0.204030559,-0.212174408,-0.219069129,-0.224722166,-0.229140412,-0.232335686,-0.234324563,-0.235128195,-0.234772114,-0.233286033,-0.230703633,-0.227062344,-0.222403111,-0.216770161,-0.210210748,-0.202774891,-0.194515104,-0.185486099,-0.175744476,-0.165348396,-0.15435722,-0.142831123,-0.130830669,-0.118416354,-0.105648092,-0.092584657,-0.079283065,-0.065797888,-0.0521805,-0.03847825,-0.024733545,-0.010982868,0.002744306,0.016426655,0.030052231,0.043619747,0.05713988,0.070636605,0.08414848,0.097729873,0.111452039,0.125404005,0.13969316,0.154445482,0.169805275,0.185934346,0.203010488,0.2212252,0.240780542,0.261885086,0.284748919,0.309577733,0.336566048,0.365889711,0.397699038,0.432104409,0.46917993,0.508943272,0.551354277,0.596307363,0.643626542,0.693062173,0.744289752,0.79691098,0.85045728,0.904395871,0.958138449,1.011054559,1.062474568,1.111727029,1.158135105,1.201050821,1.239852328,1.274006058,1.303044695,1.326605954,1.344443447,1.356437773,1.362602695,1.363085725,1.358162799,1.348227142,1.333772923,1.315374704,1.293664024,1.269304678,1.242968236,1.21531127,1.186955477,1.158471522,1.130367088,1.103079209,1.076970655,1.052329922,1.029374161,1.008254396,0.989062282,0.971837799,0.95657215,0.94324228,0.931767062,0.922058291,0.914012643,0.907516917,0.902452436,0.898698641,0.896143482,0.894659668,0.89413892,0.894475371,0.895569834,0.897330209,0.899671635,0.902516442,0.905793969,0.909440266,0.913397733,0.91761471,0.922045055,0.926647697,0.931386217,0.93622842,0.941145943,0.94611388,0.95111043,0.956116576,0.961115792,0.966093766,0.971038162,0.975938391,0.980785418,0.985571579,0.99029042,0.994936555,0.999505539,1.003993753,1.0083983,1.012716921,1.016947912,1.021090055,1.025142554,1.029104983,1.032977233,1.036759475,1.040452117,1.044055774,1.047571238,1.050999451,1.054341482,1.057598512,1.060771808,1.063862715,1.066872639,1.069803036,1.072655401,1.075431258,1.078132156,1.080759655,1.083315329,1.085800751,1.088217496,1.090567133,1.092851222,1.095071313,1.097228939,1.099325619,1.101362852,1.103342119,1.105264876,1.107132561,1.108046193];
    var _htLMS_F_M=[84.97555512,85.3973169,86.29026318,87.15714182,87.9960184,88.8055115,89.58476689,90.33341722,91.0515436,91.7396352,92.39854429,93.02945392,93.63382278,94.21335709,94.79643239,95.37391918,95.94692677,96.51644912,97.08337211,97.6484807,98.21246579,98.77593069,99.33939735,99.9033122,100.4680516,101.033927,101.6011898,102.1700358,102.7406094,103.3130077,103.8872839,104.4634511,105.0414853,105.6213287,106.2028921,106.7860583,107.3706841,107.9566031,108.5436278,109.1315521,109.7201531,110.3091934,110.8984228,111.4875806,112.0763967,112.6645943,113.2518902,113.8380006,114.4226317,115.0054978,115.5863089,116.1647782,116.7406221,117.3135622,117.8833259,118.4496481,119.0122722,119.5709513,120.1254495,120.6755427,121.22102,121.7616844,122.2973542,122.827864,123.3530652,123.8728276,124.38704,124.8956114,125.398472,125.895574,126.3868929,126.8724284,127.3522056,127.8262759,128.2947187,128.757642,129.2151839,129.6675143,130.1148354,130.5573839,130.995432,131.4292887,131.8593015,132.2858574,132.7093845,133.1303527,133.5492749,133.9667073,134.3832499,134.7995463,135.2162826,135.634186,136.0540223,136.4765925,136.9027281,137.3332846,137.7691339,138.2111552,138.6602228,139.1171933,139.5828898,140.0580848,140.5434787,141.0396832,141.5471945,142.0663731,142.59742,143.1403553,143.6949981,144.2609497,144.8375809,145.4240246,146.0191748,146.621692,147.2300177,147.8423918,148.4568879,149.0714413,149.6838943,150.2920328,150.8936469,151.4865636,152.0686985,152.6380955,153.1929631,153.7317031,154.2529332,154.755501,155.2384904,155.7012216,156.1432438,156.564323,156.9644258,157.3436995,157.7024507,158.0411233,158.3602756,158.6605588,158.9426964,159.2074654,159.455679,159.688172,159.9057871,160.1093647,160.299733,160.4776996,160.6440526,160.7995428,160.9448916,161.0807857,161.2078755,161.3267744,161.4380593,161.5422726,161.639917,161.7314645,161.8173534,161.8979913,161.9737558,162.0449969,162.1120386,162.17518,162.2346979,162.2908474,162.343864,162.3939652,162.4413513,162.4862071,162.5287029,162.5689958,162.6072309,162.6435418,162.6780519,162.7108751,162.7421168,162.7718741,162.8002371,162.8272889,162.8531067,162.8777619,162.9013208,162.9238449,162.9453912,162.9660131,162.9857599,163.0046776,163.0228094,163.0401953,163.0568727,163.0728768,163.0882404,163.1029943,163.1171673,163.1307866,163.1438776,163.1564644,163.1685697,163.1802146,163.1914194,163.202203,163.2125835,163.2225779,163.2322024,163.2414722,163.2504019,163.2590052,163.2672954,163.2752848,163.2829854,163.2904086,163.297565,163.304465,163.3111185,163.3175349,163.3237231,163.3296918,163.3354491,163.338251];
    var _htLMS_F_S=[0.040791394,0.040859727,0.041142161,0.041349399,0.041500428,0.041610508,0.041691761,0.04175368,0.041803562,0.041846882,0.041887626,0.041928568,0.041971514,0.042017509,0.042104522,0.042199507,0.042300333,0.042405225,0.042512706,0.042621565,0.042730809,0.042839638,0.042947412,0.043053626,0.043157889,0.043259907,0.043359463,0.043456406,0.043550638,0.043642107,0.043730791,0.043816701,0.043899867,0.043980337,0.044058171,0.04413344,0.044206218,0.044276588,0.044344632,0.044410436,0.044474084,0.044535662,0.044595254,0.044652942,0.044708809,0.044762936,0.044815402,0.044866288,0.044915672,0.044963636,0.045010259,0.045055624,0.045099817,0.045142924,0.045185036,0.045226249,0.045266662,0.045306383,0.045345524,0.045384203,0.045422551,0.045460702,0.045498803,0.045537012,0.045575495,0.045614432,0.045654016,0.04569445,0.045735953,0.045778759,0.045823114,0.04586928,0.045917535,0.045968169,0.04602149,0.046077818,0.046137487,0.046200842,0.04626824,0.046340046,0.046416629,0.046498361,0.046585611,0.046678741,0.046778099,0.04688401,0.046996769,0.047116633,0.047243801,0.047378413,0.047520521,0.047670085,0.047826946,0.04799081,0.048161228,0.04833757,0.048519011,0.048704503,0.048892759,0.049082239,0.049271137,0.049457371,0.049638596,0.049812203,0.049975355,0.050125012,0.050257992,0.050371024,0.050460835,0.050524236,0.050558224,0.050560083,0.050527494,0.050458634,0.050352269,0.050207825,0.050025434,0.049805967,0.049551023,0.049262895,0.048944504,0.048599314,0.048231224,0.047844442,0.047443362,0.04703243,0.046616026,0.046198356,0.04578335,0.045374597,0.044975281,0.044588148,0.044215488,0.043859135,0.04352048,0.043200497,0.042899776,0.042618565,0.042356812,0.042114211,0.041890247,0.04168424,0.041495379,0.041322765,0.041165437,0.041022401,0.040892651,0.040775193,0.040669052,0.040573288,0.040487005,0.040409354,0.040339537,0.040276811,0.040220488,0.040169932,0.040124562,0.040083845,0.040047295,0.040014473,0.03998498,0.039958458,0.039934584,0.039913066,0.039893644,0.039876087,0.039860185,0.039845754,0.039832629,0.039820663,0.039809725,0.0397997,0.039790485,0.039781991,0.039774136,0.03976685,0.03976007,0.039753741,0.039747815,0.039742249,0.039737004,0.039732048,0.039727352,0.03972289,0.03971864,0.039714581,0.039710697,0.039706971,0.039703391,0.039699945,0.039696623,0.039693415,0.039690313,0.039687311,0.039684402,0.039681581,0.039678842,0.039676182,0.039673596,0.039671082,0.039668635,0.039666254,0.039663936,0.039661679,0.039659481,0.039657339,0.039655252,0.039653218,0.039651237,0.039649306,0.039647424,0.039645591,0.039643804,0.039642063,0.039640367,0.039638715,0.039637105,0.039636316];
    var _htLMS_M_L=[0.941523967,1.00720807,0.837251351,0.681492975,0.538779654,0.407697153,0.286762453,0.174489485,0.069444521,-0.029720564,-0.124251789,-0.215288396,-0.30385434,-0.390918369,-0.254801167,-0.125654535,-0.00316735,0.11291221,0.222754969,0.326530126,0.42436156,0.516353108,0.602595306,0.683170764,0.758158406,0.827636736,0.891686306,0.95039153,1.003830006,1.05213569,1.0953669,1.133652119,1.167104213,1.195845353,1.220004233,1.239715856,1.255121285,1.266367398,1.273606657,1.276996893,1.276701119,1.272887366,1.265728536,1.255402281,1.242090871,1.225981067,1.207263978,1.186140222,1.162796198,1.137442868,1.110286487,1.081536236,1.05140374,1.020102497,0.987847213,0.954853043,0.921334742,0.887505723,0.85357703,0.819756239,0.786246296,0.753244292,0.720940222,0.689515708,0.659142731,0.629997853,0.602203984,0.575908038,0.55123134,0.528279901,0.507143576,0.487895344,0.470590753,0.455267507,0.441945241,0.430625458,0.421291648,0.413909588,0.408427813,0.404778262,0.402877077,0.402625561,0.40391127,0.406609232,0.410583274,0.415687443,0.421767514,0.428662551,0.436206531,0.44423,0.45256176,0.461030578,0.469466904,0.477704608,0.48558272,0.492947182,0.499652617,0.505564115,0.510559047,0.514528903,0.517381177,0.519041285,0.519454524,0.518588072,0.516433004,0.513006312,0.508352901,0.502547502,0.495696454,0.487939275,0.479449924,0.470437652,0.461147305,0.451858946,0.442886661,0.434576385,0.427302633,0.421464027,0.417477538,0.415771438,0.416777012,0.420919142,0.428606007,0.440218167,0.456097443,0.476536014,0.501766234,0.531951655,0.567179725,0.607456565,0.652704121,0.702759868,0.757379106,0.816239713,0.878947416,0.945053486,1.014046108,1.085383319,1.158487278,1.232768816,1.307628899,1.382473225,1.456720479,1.529810247,1.601219573,1.670433444,1.736995571,1.800483802,1.860518777,1.916765525,1.968934444,2.016781776,2.060109658,2.098765817,2.132642948,2.16167779,2.185849904,2.205180153,2.219728869,2.2295937,2.234907144,2.235833767,2.232567138,2.2253265,2.214353232,2.199905902,2.182262864,2.161704969,2.138524662,2.113023423,2.085490286,2.0562195,2.025496648,1.993598182,1.960789092,1.927320937,1.89343024,1.859337259,1.825245107,1.791339209,1.757787065,1.724738292,1.692324905,1.660661815,1.629847495,1.599964788,1.571081817,1.543252982,1.516519998,1.490912963,1.466451429,1.44314546,1.420996665,1.399999187,1.380140651,1.361403047,1.343763564,1.327195355,1.311668242,1.297149359,1.283603728,1.270994782,1.25928483,1.248435461,1.23840791,1.229163362,1.220663228,1.212869374,1.20574431,1.199251356,1.19335477,1.188019859,1.183213059,1.178901998,1.175055543,1.171643828,1.16863827,1.167279219];
    var _htLMS_M_M=[86.45220101,86.86160934,87.65247282,88.42326434,89.17549228,89.91040853,90.62907762,91.33242379,92.02127167,92.69637946,93.35846546,94.00822923,94.64636981,95.27359106,95.91474929,96.54734328,97.17191309,97.78897727,98.3990283,99.00254338,99.599977,100.191764,100.7783198,101.3600411,101.9373058,102.5104735,103.0798852,103.645864,104.208713,104.7687256,105.3261638,105.8812823,106.4343146,106.9854769,107.534968,108.0829695,108.6296457,109.1751441,109.7195954,110.2631136,110.8057967,111.3477265,111.8889694,112.4295761,112.9695827,113.5090108,114.0478678,114.5861486,115.1238315,115.6608862,116.1972691,116.732925,117.2677879,117.8017819,118.3348215,118.8668123,119.397652,119.9272309,120.455433,120.9821362,121.5072136,122.0305342,122.5519634,123.0713645,123.588599,124.1035312,124.6160161,125.1259182,125.6331012,126.1374319,126.6387804,127.1370217,127.6320362,128.1237104,128.6119383,129.096622,129.5776723,130.0550101,130.5285669,130.9982857,131.4641218,131.9260439,132.3840348,132.838092,133.2882291,133.7344759,134.1768801,134.6155076,135.0504433,135.4817925,135.9096813,136.3342577,136.7556923,137.1741794,137.5899378,138.0032114,138.4142703,138.8234114,139.2309592,139.6372663,140.042714,140.4477127,140.8527022,141.2581515,141.6645592,142.072452,142.4823852,142.8949403,143.3107241,143.7303663,144.1545167,144.5838414,145.0190192,145.4607359,145.9096784,146.3665278,146.8319513,147.3065929,147.7910635,148.2859294,148.7917006,149.3088178,149.8376391,150.3784267,150.9313331,151.4963887,152.0734897,152.6623878,153.2626819,153.8738124,154.495058,155.1255365,155.7642086,156.4098858,157.0612415,157.7168289,158.3750929,159.034399,159.6930501,160.3493168,161.0014586,161.6477515,162.2865119,162.9161202,163.535045,164.1418486,164.7352199,165.3139755,165.8770715,166.4236087,166.9528354,167.4641466,167.9570814,168.4313175,168.8866644,169.3230548,169.7405351,170.139255,170.5194567,170.881464,171.2256717,171.5525345,171.8625576,172.1562865,172.4342983,172.6971935,172.9455898,173.180112,173.4013896,173.6100518,173.8067179,173.9919998,174.1664951,174.3307855,174.4854344,174.6309856,174.7679617,174.8968634,175.0181691,175.1323345,175.2397926,175.340954,175.4362071,175.5259191,175.6104358,175.690083,175.7651671,175.8359757,175.9027788,175.9658293,176.0253641,176.081605,176.1347593,176.1850208,176.2325707,176.2775781,176.3202008,176.3605864,176.3988725,176.4351874,176.469651,176.5023751,176.533464,176.5630153,176.5911197,176.6178621,176.6433219,176.6675729,176.6906844,176.712721,176.733743,176.753807,176.7729657,176.7912687,176.8087622,176.8254895,176.8414914,176.8492322];
    var _htLMS_M_S=[0.040321528,0.040395626,0.040577525,0.040723122,0.040833194,0.040909059,0.040952433,0.04096533,0.040949976,0.040908737,0.040844062,0.040758431,0.040654312,0.04053412,0.040572876,0.04061691,0.040666414,0.040721467,0.040782045,0.040848042,0.040919281,0.040995524,0.041076485,0.041161838,0.041251224,0.041344257,0.041440534,0.041539635,0.041641136,0.041744602,0.041849607,0.041955723,0.042062532,0.042169628,0.042276619,0.042383129,0.042488804,0.042593311,0.042696342,0.042797615,0.042896877,0.042993904,0.043088503,0.043180513,0.043269806,0.043356287,0.043439893,0.043520597,0.043598407,0.043673359,0.043745523,0.043815003,0.043881929,0.043946461,0.044008785,0.044069112,0.044127675,0.044184725,0.044240532,0.044295379,0.044349559,0.044403374,0.04445713,0.044511135,0.044565693,0.044621104,0.044677662,0.044735646,0.044795322,0.044856941,0.04492073,0.044986899,0.045055632,0.045127088,0.045201399,0.045278671,0.045358979,0.045442372,0.045528869,0.045618459,0.045711105,0.045806742,0.045905281,0.046006604,0.046110573,0.046217028,0.04632579,0.046436662,0.04654943,0.046663871,0.046779748,0.046896817,0.047014827,0.047133525,0.047252654,0.047371961,0.047491194,0.047610108,0.047728463,0.04784603,0.047962592,0.048077942,0.048191889,0.048304259,0.048414893,0.048523648,0.048630402,0.04873505,0.048837504,0.048937694,0.049035564,0.049131073,0.049224189,0.049314887,0.049403145,0.049488934,0.049572216,0.049652935,0.049731004,0.0498063,0.04987865,0.049947823,0.050013518,0.050075353,0.050132858,0.050185471,0.050232532,0.050273285,0.050306885,0.050332406,0.05034886,0.050355216,0.050350423,0.050333444,0.050303283,0.050259018,0.050199837,0.050125062,0.05003418,0.049926861,0.049802977,0.04966261,0.049506051,0.049333801,0.049146553,0.04894519,0.048730749,0.048504404,0.048267442,0.04802123,0.047767192,0.047506783,0.047241456,0.04697265,0.046701759,0.046430122,0.046159004,0.045889585,0.045622955,0.045360101,0.045101913,0.044849174,0.044602566,0.044362674,0.044129985,0.043904897,0.043687723,0.043478698,0.043277987,0.043085685,0.042901835,0.042726424,0.042559396,0.042400652,0.042250063,0.042107465,0.041972676,0.041845488,0.041725679,0.041613015,0.041507249,0.041408129,0.041315398,0.041228796,0.04114806,0.041072931,0.04100315,0.040938463,0.040878617,0.040823368,0.040772475,0.040725706,0.040682834,0.04064364,0.040607913,0.040575448,0.040546051,0.040519532,0.040495713,0.040474421,0.040455493,0.040438773,0.040424111,0.040411366,0.040400405,0.040391101,0.040383334,0.04037699,0.040371962,0.040368149,0.040365456,0.040363795,0.04036308,0.040363233,0.040364179,0.04036585,0.04036818,0.040369574];

    // BP Rosner spline coefficients (99 percentiles x 13 coefficients)
    var _bpCoeff_F_SYS=[
[-7.4855,-1.2252,1.2643,-6.8797,20.4744,0.7114,-0.0066,-0.0667,0.3564,-0.0012,0.5278,-0.6927,0.1388],
[8.4462,-0.9598,0.9046,-5.1098,15.1548,0.5919,-0.0029,-0.065,0.2495,-0.003,0.4421,-0.5724,0.0997],
[26.6223,-1.1479,1.2134,-8.4665,28.0408,0.475,0.0001,-0.0643,0.2062,-0.023,0.5561,-0.7467,0.185],
[31.8947,-0.867,1.1693,-8.2932,26.0849,0.4251,-0.0002,-0.0535,0.1718,-0.008,0.3954,-0.5402,0.1473],
[30.9472,-1.1288,1.5926,-11.7371,34.5934,0.4578,-0.0019,-0.0341,0.1144,-0.0167,0.6897,-1.0025,0.3867],
[23.152,-1.1368,1.751,-13.8556,41.2104,0.527,-0.0048,-0.0149,0.0623,0.0062,0.4347,-0.6509,0.2798],
[19.3036,-0.923,1.6566,-14.2294,42.9522,0.5494,-0.0062,-0.0051,0.0555,0.0242,0.1295,-0.1986,0.0876],
[20.0191,-1.0378,1.6928,-13.6476,40.8615,0.5596,-0.0071,0.0146,-0.03,0.0135,0.1632,-0.2423,0.1013],
[21.6515,-0.9745,1.5964,-13.0096,38.8309,0.5462,-0.0063,0.0087,-0.0183,0.0093,0.2644,-0.3848,0.1477],
[22.6952,-0.8665,1.4799,-11.8203,34.2277,0.537,-0.0066,0.0176,-0.0648,0.0046,0.3226,-0.4689,0.1811],
[23.1615,-0.8132,1.4422,-11.8893,34.8542,0.5329,-0.0063,0.013,-0.0367,0.008,0.34,-0.5072,0.2171],
[27.9,-0.8288,1.4257,-11.5803,33.7393,0.4995,-0.0049,0.0013,0.0117,-0.0014,0.4954,-0.7333,0.3051],
[34.8678,-0.801,1.429,-11.2835,32.3656,0.4469,-0.0037,-0.0037,0.0274,-0.0004,0.3936,-0.5873,0.251],
[37.7557,-0.9638,1.5603,-11.545,31.5671,0.4392,-0.0035,0.0024,-0.0164,-0.0087,0.395,-0.575,0.2238],
[39.9509,-1.0185,1.6189,-11.6485,31.009,0.4284,-0.0032,0.0051,-0.0452,-0.0101,0.3516,-0.5073,0.1906],
[40.8576,-0.9313,1.5386,-11.5031,31.8413,0.418,-0.0029,0.0019,-0.0291,-0.0081,0.3507,-0.5094,0.1968],
[42.1455,-0.9104,1.5356,-11.4411,31.5567,0.4098,-0.0029,0.0038,-0.0368,-0.006,0.2848,-0.4155,0.1642],
[44.0009,-1.0103,1.6565,-11.8711,31.8672,0.4038,-0.0026,0.0007,-0.0172,-0.0017,0.1877,-0.2802,0.1211],
[42.9483,-0.9479,1.6532,-12.4439,34.3937,0.4097,-0.0029,0.0023,-0.0231,-0.0003,0.1892,-0.2761,0.1077],
[43.4489,-0.9355,1.5751,-11.4463,30.9525,0.4076,-0.0027,0,-0.0199,0.0013,0.1619,-0.2376,0.0949],
[42.0432,-0.9668,1.5892,-11.2769,29.6658,0.4235,-0.003,0.0009,-0.0194,0.0051,0.1181,-0.1781,0.0784],
[43.3921,-0.9251,1.5125,-10.669,27.8566,0.4122,-0.0025,-0.0008,-0.0269,-0.0003,0.178,-0.2571,0.0962],
[43.1823,-0.9153,1.5502,-11.2058,29.7148,0.4154,-0.0028,0.0025,-0.0386,0.0053,0.0679,-0.0977,0.0352],
[43.5111,-0.8427,1.4724,-10.8634,29.5168,0.4107,-0.0027,0.0019,-0.0416,-0.0023,0.1644,-0.2282,0.0711],
[44.8115,-0.9195,1.5496,-10.7815,27.8384,0.4087,-0.003,0.012,-0.0908,-0.0063,0.1451,-0.1957,0.053],
[45.1153,-0.8419,1.4685,-10.4821,27.7389,0.404,-0.003,0.0148,-0.1094,-0.0047,0.1524,-0.2131,0.0715],
[45.0184,-0.9109,1.4637,-9.8769,25.3956,0.4124,-0.0031,0.0163,-0.1196,-0.0095,0.2128,-0.3015,0.1084],
[46.8396,-0.9336,1.4913,-10.0409,25.5791,0.4004,-0.0025,0.0087,-0.0854,-0.0083,0.207,-0.2945,0.1065],
[46.3627,-1.0691,1.6403,-10.8997,27.3749,0.4156,-0.003,0.0128,-0.0892,-0.006,0.1891,-0.2783,0.1168],
[46.056,-1.0253,1.6174,-10.8914,27.6133,0.4169,-0.0032,0.0134,-0.0831,-0.0015,0.1168,-0.1751,0.0794],
[45.8707,-1.0687,1.6929,-11.5282,29.3823,0.4234,-0.0035,0.0189,-0.1052,-0.002,0.0549,-0.0766,0.0279],
[46.225,-1.0493,1.6305,-11.0002,28.295,0.4212,-0.0032,0.015,-0.0892,0.001,0.0192,-0.0279,0.014],
[49.7043,-1.1168,1.6687,-10.6909,26.5418,0.4005,-0.0027,0.0175,-0.1166,-0.0029,-0.0064,0.0124,-0.0056],
[52.501,-1.2283,1.7174,-10.288,24.6009,0.39,-0.0025,0.0229,-0.1413,-0.0055,-0.0773,0.1151,-0.0428],
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[71.0728,-0.5897,0.954,-3.2255,5.828,0.3275,-0.0005,0.0181,-0.0707,-0.02,0.1457,-0.2721,0.1573],
[70.0217,-0.3531,0.6571,-1.1748,0.806,0.3265,-0.0006,0.0201,-0.0785,-0.0091,0.1053,-0.1976,0.115],
[70.5203,-0.3866,0.7711,-1.2734,-1.0004,0.3319,-0.0017,0.0287,-0.092,0.009,0.0424,-0.0915,0.0678],
[76.3547,-0.7212,0.9341,-1.3303,-1.6526,0.314,-0.0002,0.0247,-0.0938,-0.0122,0.0896,-0.174,0.1101],
[90.6025,-1.3557,1.1746,0.1551,-7.729,0.2521,0.0034,0.0132,-0.0881,-0.0357,0.0885,-0.1674,0.1033],
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[102.9154,-1.5899,1.4523,-0.5061,-7.5933,0.1871,0.0055,0.002,-0.0596,-0.0411,0.1113,-0.2264,0.1604],
[125.2207,-3.3398,2.9466,-5.4863,-1.908,0.1438,0.0076,0.0111,-0.0959,-0.1006,0.1222,-0.2249,0.1376],
[125.8697,-3.2997,3.1051,-7.3155,3.4281,0.1505,0.0067,0.0193,-0.1148,-0.0879,0.0819,-0.1569,0.1076],
[99.6314,-2.8535,3.065,-6.4997,-4.9829,0.3473,-0.001,0.0499,-0.1346,-0.0354,-0.0379,0.0681,-0.0284]
];

    var _bpCoeff_M_DIA=[
[-13.567,-1.1325,-1.7078,28.8607,-81.1719,0.4118,0.0003,-0.0263,0.0507,-0.0087,-0.1202,0.2977,-0.2691],
[-43.7777,1.9512,-3.8763,28.8717,-57.6407,0.4741,-0.0029,-0.0496,0.1518,-0.0191,0.1992,-0.2879,0.0508],
[-35.5221,1.6542,-3.2001,22.4882,-41.299,0.4425,-0.0025,-0.0428,0.1269,-0.0674,0.3133,-0.465,0.1062],
[-25.9772,2.0924,-3.8188,24.4956,-38.8551,0.3556,0.0003,-0.0543,0.1499,-0.0796,0.4423,-0.7299,0.2906],
[-16.9931,2.2497,-3.7873,23.1323,-35.1791,0.2916,0.0006,-0.0481,0.1416,-0.0641,0.3962,-0.6572,0.2638],
[-19.6683,2.3137,-3.7117,22.8638,-35.7152,0.3203,-0.0015,-0.0388,0.1406,-0.0689,0.4499,-0.7699,0.3469],
[-33.2858,2.7679,-4.0941,22.3138,-27.6548,0.3986,-0.0021,-0.0592,0.2053,-0.0938,0.6243,-1.0803,0.5056],
[-42.522,3.0229,-4.2155,22.1584,-27.6854,0.4632,-0.0051,-0.0392,0.1567,-0.0631,0.512,-0.8671,0.3759],
[-34.2517,2.7721,-3.6109,17.4453,-15.4161,0.4233,-0.0055,-0.0269,0.1286,-0.0371,0.366,-0.6077,0.2427],
[-42.4833,3.1554,-3.8233,16.9605,-12.0012,0.466,-0.0072,-0.0191,0.1105,-0.0294,0.3572,-0.5855,0.2225],
[-54.4375,3.0764,-3.5785,15.2542,-9.8518,0.569,-0.0112,-0.0014,0.0879,-0.034,0.4004,-0.6627,0.2631],
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[-40.8119,2.5241,-3.3547,16.1453,-12.993,0.5119,-0.0092,0.0039,0.0554,-0.0504,0.3968,-0.6637,0.2771],
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[-2.725,3.8134,-2.3052,3.5243,8.0191,0.4042,-0.0133,0.0238,0.0586,0.0627,0.0422,-0.052,-0.018]
];

    function calcHeightPctile(age, sex, heightCm) {
      var idx = Math.max(0, Math.min(217, Math.round(age * 12) - 24));
      var L, M, S;
      if (sex === 'female') { L = _htLMS_F_L[idx]; M = _htLMS_F_M[idx]; S = _htLMS_F_S[idx]; }
      else { L = _htLMS_M_L[idx]; M = _htLMS_M_M[idx]; S = _htLMS_M_S[idx]; }
      var z = (Math.pow(heightCm / M, L) - 1) / (L * S);
      return { z: z, percentile: normalCDF(z) * 100 };
    }

    function computeBPPercentile(age, sex, heightCm, bpType, bpValue) {
      var t1, t2, t3, t4, t5, ta1, ta2, ta3, ta4, ta5, tb1, tb2, tb3, tb4, tb5, w;
      if (sex === 'female') {
        t1=106.7; t2=140.7; t3=154.0; t4=160.5; t5=168.9;
        ta1=5.00; ta2=10.70; ta3=13.16; ta4=14.51; ta5=17.33;
        tb1=6.701; tb2=16.438; tb3=46.80; tb4=84.46; tb5=203.608;
        w = (age - 10) * (heightCm - 147);
      } else {
        t1=107.8; t2=140.0; t3=154.5; t4=166.4; t5=179.1;
        ta1=5.06; ta2=10.79; ta3=13.22; ta4=14.51; ta5=17.30;
        tb1=-15; tb2=8.9; tb3=50.375; tb4=112.684; tb5=250.04;
        w = (age - 10) * (heightCm - 150);
      }

      var x = heightCm, y = age;

      // Height restricted cubic splines
      var x2a = Math.max(0, x - t1); var x2b = Math.max(0, x - t4); var x2c = Math.max(0, x - t5);
      var x2 = Math.pow(x2a,3) - Math.pow(x2b,3)*(t5-t1)/(t5-t4) + Math.pow(x2c,3)*(t4-t1)/(t5-t4);
      var x3a = Math.max(0, x - t2);
      var x3 = Math.pow(x3a,3) - Math.pow(x2b,3)*(t5-t2)/(t5-t4) + Math.pow(x2c,3)*(t4-t2)/(t5-t4);
      var x4a = Math.max(0, x - t3);
      var x4 = Math.pow(x4a,3) - Math.pow(x2b,3)*(t5-t3)/(t5-t4) + Math.pow(x2c,3)*(t4-t3)/(t5-t4);
      var x2s = x2/100, x3s = x3/100, x4s = x4/100;

      // Age restricted cubic splines
      var y2a = Math.max(0, y - ta1); var y2b = Math.max(0, y - ta4); var y2c = Math.max(0, y - ta5);
      var y2 = Math.pow(y2a,3) - Math.pow(y2b,3)*(ta5-ta1)/(ta5-ta4) + Math.pow(y2c,3)*(ta4-ta1)/(ta5-ta4);
      var y3a = Math.max(0, y - ta2);
      var y3 = Math.pow(y3a,3) - Math.pow(y2b,3)*(ta5-ta2)/(ta5-ta4) + Math.pow(y2c,3)*(ta4-ta2)/(ta5-ta4);
      var y4a = Math.max(0, y - ta3);
      var y4 = Math.pow(y4a,3) - Math.pow(y2b,3)*(ta5-ta3)/(ta5-ta4) + Math.pow(y2c,3)*(ta4-ta3)/(ta5-ta4);
      var y2s = y2/100, y3s = y3/100, y4s = y4/100;

      // Interaction restricted cubic splines
      var w2a = Math.max(0, w - tb1); var w2b = Math.max(0, w - tb4); var w2c = Math.max(0, w - tb5);
      var w2 = Math.pow(w2a,3) - Math.pow(w2b,3)*(tb5-tb1)/(tb5-tb4) + Math.pow(w2c,3)*(tb4-tb1)/(tb5-tb4);
      var w3a = Math.max(0, w - tb2);
      var w3 = Math.pow(w3a,3) - Math.pow(w2b,3)*(tb5-tb2)/(tb5-tb4) + Math.pow(w2c,3)*(tb4-tb2)/(tb5-tb4);
      var w4a = Math.max(0, w - tb3);
      var w4 = Math.pow(w4a,3) - Math.pow(w2b,3)*(tb5-tb3)/(tb5-tb4) + Math.pow(w2c,3)*(tb4-tb3)/(tb5-tb4);
      var w2s = w2/10000, w3s = w3/10000, w4s = w4/10000;

      // Select coefficient array
      var coeff;
      if (sex === 'female') coeff = (bpType === 'sys') ? _bpCoeff_F_SYS : _bpCoeff_F_DIA;
      else coeff = (bpType === 'sys') ? _bpCoeff_M_SYS : _bpCoeff_M_DIA;

      // Compute predicted BP at each percentile and find closest match
      var fxsys = new Array(99);
      for (var i = 0; i < 99; i++) {
        fxsys[i] = coeff[i][0] + coeff[i][5]*x + coeff[i][6]*x2s + coeff[i][7]*x3s + coeff[i][8]*x4s
                  + coeff[i][1]*y + coeff[i][2]*y2s + coeff[i][3]*y3s + coeff[i][4]*y4s
                  + coeff[i][9]*w + coeff[i][10]*w2s + coeff[i][11]*w3s + coeff[i][12]*w4s;
      }

      var minDiff = Infinity, percentile = 50;
      for (var i = 0; i < 99; i++) {
        var diff = Math.abs(bpValue - fxsys[i]);
        if (diff < minDiff) { minDiff = diff; percentile = i + 1; }
      }
      return { percentile: percentile, predicted: fxsys };
    }

    function classifyBPFromPercentiles(age, sysPctile, diaPctile, sys, dia) {
      var sysClass, diaClass;

      if (age >= 13) {
        // Ages >= 13: use absolute thresholds per AAP 2017
        if (sys >= 140)      sysClass = 'stage2';
        else if (sys >= 130) sysClass = 'stage1';
        else if (sys >= 120) sysClass = 'elevated';
        else                 sysClass = 'normal';

        if (dia >= 90)       diaClass = 'stage2';
        else if (dia >= 80)  diaClass = 'stage1';
        else                 diaClass = 'normal';
      } else {
        // Ages 1-<13: use percentile thresholds
        if (sysPctile >= 95 + 12 || sys >= 140) sysClass = 'stage2';
        else if (sysPctile >= 95 || sys >= 130)  sysClass = 'stage1';
        else if (sysPctile >= 90 || sys >= 120)  sysClass = 'elevated';
        else                                      sysClass = 'normal';

        if (diaPctile >= 95 + 12 || dia >= 90) diaClass = 'stage2';
        else if (diaPctile >= 95 || dia >= 80)  diaClass = 'stage1';
        else if (diaPctile >= 90)               diaClass = 'elevated';
        else                                     diaClass = 'normal';
      }

      var levels = { normal: 0, elevated: 1, stage1: 2, stage2: 3 };
      var overall = levels[sysClass] >= levels[diaClass] ? sysClass : diaClass;

      return { sysClass: sysClass, diaClass: diaClass, classification: overall };
    }

    var classLabels = {
      normal: { text: 'Normal', color: '#10b981', bg: '#d1fae5' },
      elevated: { text: 'Elevated', color: '#f59e0b', bg: '#fef3c7' },
      stage1: { text: 'Stage 1 Hypertension', color: '#f97316', bg: '#ffedd5' },
      stage2: { text: 'Stage 2 Hypertension', color: '#ef4444', bg: '#fee2e2' }
    };

    document.getElementById('btn-calc-bp').addEventListener('click', function() {
      var age = parseFloat(document.getElementById('bp-age').value);
      var sex = document.getElementById('bp-sex').value;
      var sys = parseFloat(document.getElementById('bp-systolic').value);
      var dia = parseFloat(document.getElementById('bp-diastolic').value);
      var heightCm = parseFloat(document.getElementById('bp-height').value);

      if (!age || !sex || !sys || !dia || !heightCm) { showToast('Fill in all fields including height', 'error'); return; }
      if (age < 1 || age > 17) { showToast('Age must be 1-17 years', 'error'); return; }

      var htResult = calcHeightPctile(age, sex, heightCm);
      var sysResult = computeBPPercentile(age, sex, heightCm, 'sys', sys);
      var diaResult = computeBPPercentile(age, sex, heightCm, 'dia', dia);

      var bpClass = classifyBPFromPercentiles(age, sysResult.percentile, diaResult.percentile, sys, dia);

      // Get 50th, 90th, 95th predicted values for display
      var sys50 = sysResult.predicted[49].toFixed(0), sys90 = sysResult.predicted[89].toFixed(0), sys95 = sysResult.predicted[94].toFixed(0);
      var dia50 = diaResult.predicted[49].toFixed(0), dia90 = diaResult.predicted[89].toFixed(0), dia95 = diaResult.predicted[94].toFixed(0);

      var cl = classLabels[bpClass.classification];
      var resultDiv = document.getElementById('bp-result');
      resultDiv.classList.remove('hidden');
      resultDiv.innerHTML =
        '<div class="calc-result-header" style="background:' + cl.bg + ';border-color:' + cl.color + ';">' +
          '<div style="font-size:18px;font-weight:700;color:' + cl.color + ';">' + cl.text + '</div>' +
          '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + sys + '/' + dia + ' mmHg &mdash; ' + age + ' year old ' + sex + ', ' + heightCm + ' cm</div>' +
        '</div>' +
        '<div class="calc-result-grid">' +
          '<div class="calc-result-item">' +
            '<div class="calc-result-label">Systolic</div>' +
            '<div class="calc-result-value">' + sysResult.percentile + '<span style="font-size:12px;">th %ile</span></div>' +
            '<div class="calc-result-sub" style="color:' + classLabels[bpClass.sysClass].color + ';">' + classLabels[bpClass.sysClass].text + '</div>' +
          '</div>' +
          '<div class="calc-result-item">' +
            '<div class="calc-result-label">Diastolic</div>' +
            '<div class="calc-result-value">' + diaResult.percentile + '<span style="font-size:12px;">th %ile</span></div>' +
            '<div class="calc-result-sub" style="color:' + classLabels[bpClass.diaClass].color + ';">' + classLabels[bpClass.diaClass].text + '</div>' +
          '</div>' +
          '<div class="calc-result-item">' +
            '<div class="calc-result-label">Height</div>' +
            '<div class="calc-result-value">' + Math.round(htResult.percentile) + '<span style="font-size:12px;">th %ile</span></div>' +
            '<div class="calc-result-sub">Z = ' + htResult.z.toFixed(2) + '</div>' +
          '</div>' +
          '<div class="calc-result-item">' +
            '<div class="calc-result-label">Reference (50th %ile)</div>' +
            '<div class="calc-result-value" style="font-size:16px;">' + sys50 + '/' + dia50 + '</div>' +
            '<div class="calc-result-sub">90th: ' + sys90 + '/' + dia90 + ' &bull; 95th: ' + sys95 + '/' + dia95 + '</div>' +
          '</div>' +
        '</div>' +
        '<p style="font-size:11px;color:var(--g400);margin:12px 0 0;">BCM/Rosner quantile regression percentiles adjusted to patient height. AAP 2017 classification.</p>';

      // Generate BP curves across ages 1-17 for this sex/height
      renderBPChart(age, sex, heightCm, sys, dia);
    });


    function renderBPChart(patientAge, sex, heightCm, patientSys, patientDia) {
      if (typeof Chart === 'undefined') return;
      var container = document.getElementById('bp-chart-container');
      if (!container) return;
      container.classList.remove('hidden');
      if (_chartInstances['bp-chart-canvas']) { _chartInstances['bp-chart-canvas'].destroy(); _chartInstances['bp-chart-canvas'] = null; }

      // Generate percentile curves across ages 1-17
      var sys50 = [], sys90 = [], sys95 = [], dia50 = [], dia90 = [], dia95 = [];
      for (var a = 1; a <= 17; a++) {
        var sr = computeBPPercentile(a, sex, heightCm, 'sys', 100);
        var dr = computeBPPercentile(a, sex, heightCm, 'dia', 60);
        sys50.push({x:a, y:Math.round(sr.predicted[49])}); sys90.push({x:a, y:Math.round(sr.predicted[89])}); sys95.push({x:a, y:Math.round(sr.predicted[94])});
        dia50.push({x:a, y:Math.round(dr.predicted[49])}); dia90.push({x:a, y:Math.round(dr.predicted[89])}); dia95.push({x:a, y:Math.round(dr.predicted[94])});
      }

      var datasets = [
        { label: 'SBP 95th', data: sys95, borderColor: 'rgba(239,68,68,0.7)', borderWidth: 2, borderDash: [4,4], pointRadius: 0, fill: false, tension: 0.3 },
        { label: 'SBP 90th', data: sys90, borderColor: 'rgba(249,115,22,0.6)', borderWidth: 1.5, borderDash: [3,3], pointRadius: 0, fill: false, tension: 0.3 },
        { label: 'SBP 50th', data: sys50, borderColor: 'rgba(16,185,129,0.8)', borderWidth: 2, pointRadius: 0, fill: false, tension: 0.3 },
        { label: 'DBP 95th', data: dia95, borderColor: 'rgba(239,68,68,0.4)', borderWidth: 1.5, borderDash: [4,4], pointRadius: 0, fill: false, tension: 0.3 },
        { label: 'DBP 90th', data: dia90, borderColor: 'rgba(249,115,22,0.3)', borderWidth: 1, borderDash: [3,3], pointRadius: 0, fill: false, tension: 0.3 },
        { label: 'DBP 50th', data: dia50, borderColor: 'rgba(16,185,129,0.4)', borderWidth: 1.5, pointRadius: 0, fill: false, tension: 0.3 },
        { label: 'Patient SBP', data: [{x:patientAge, y:patientSys}], backgroundColor: '#2563eb', borderColor: '#1d4ed8', pointRadius: 8, pointHoverRadius: 10, showLine: false, type: 'scatter', order: 0 },
        { label: 'Patient DBP', data: [{x:patientAge, y:patientDia}], backgroundColor: '#7c3aed', borderColor: '#6d28d9', pointRadius: 8, pointHoverRadius: 10, pointStyle: 'triangle', showLine: false, type: 'scatter', order: 0 }
      ];

      _chartInstances['bp-chart-canvas'] = new Chart(document.getElementById('bp-chart-canvas'), {
        type: 'line',
        data: { datasets: datasets },
        options: {
          responsive: true, maintainAspectRatio: true, aspectRatio: 1.6,
          animation: { duration: 300 },
          scales: {
            x: { type: 'linear', title: { display: true, text: 'Age (years)', font: { size: 12, weight: 'bold' } }, min: 1, max: 17, ticks: { stepSize: 1 }, grid: { color: 'rgba(0,0,0,0.05)' } },
            y: { title: { display: true, text: 'Blood Pressure (mmHg)', font: { size: 12, weight: 'bold' } }, min: 30, grid: { color: 'rgba(0,0,0,0.05)' } }
          },
          plugins: {
            legend: { display: true, position: 'bottom', labels: { font: { size: 10 }, usePointStyle: true } },
            tooltip: {
              callbacks: {
                label: function(ctx) {
                  if (ctx.dataset.label.indexOf('Patient') !== -1) return ctx.dataset.label + ': ' + ctx.parsed.y + ' mmHg';
                  return ctx.dataset.label + ': ' + ctx.parsed.y + ' mmHg at age ' + ctx.parsed.x;
                }
              }
            }
          }
        }
      });
    }

    document.getElementById('btn-clear-bp').addEventListener('click', function() {
      ['bp-age', 'bp-sex', 'bp-height', 'bp-systolic', 'bp-diastolic'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      document.getElementById('bp-result').classList.add('hidden');
      var bpc = document.getElementById('bp-chart-container'); if (bpc) bpc.classList.add('hidden');
    });

    // ═══════════════════════════════════════════════════════════
    // BMI PERCENTILE — CDC 2000
    // ═══════════════════════════════════════════════════════════

    // CDC BMI-for-Age 24-240mo (every 3 months, from CDC bmiagerev.csv)
    var bmiLMS = {male:{24:{L:-1.982374,M:16.5478,S:0.080127},30:{L:-1.642107,M:16.2497,S:0.075499},36:{L:-1.419991,M:16.0003,S:0.072634},42:{L:-1.438165,M:15.7941,S:0.071495},48:{L:-1.714869,M:15.6282,S:0.071889},54:{L:-2.155348,M:15.5026,S:0.073491},60:{L:-2.615166,M:15.4191,S:0.075992},66:{L:-2.981797,M:15.3795,S:0.079211},72:{L:-3.211705,M:15.3835,S:0.083048},78:{L:-3.314769,M:15.429,S:0.0874},84:{L:-3.323189,M:15.5129,S:0.092131},90:{L:-3.270455,M:15.6317,S:0.097082},96:{L:-3.183058,M:15.7823,S:0.102091},102:{L:-3.079383,M:15.9617,S:0.107013},108:{L:-2.971148,M:16.1671,S:0.111721},114:{L:-2.865311,M:16.3961,S:0.116113},120:{L:-2.765648,M:16.6461,S:0.120112},126:{L:-2.673903,M:16.9151,S:0.123664},132:{L:-2.59056,M:17.2009,S:0.126735},138:{L:-2.51532,M:17.5014,S:0.129309},144:{L:-2.447426,M:17.8146,S:0.131389},150:{L:-2.385858,M:18.1387,S:0.132991},156:{L:-2.329457,M:18.4718,S:0.134141},162:{L:-2.277017,M:18.812,S:0.13488},168:{L:-2.227362,M:19.1576,S:0.135251},174:{L:-2.179426,M:19.5067,S:0.135309},180:{L:-2.132345,M:19.8577,S:0.13511},186:{L:-2.085574,M:20.2086,S:0.134718},192:{L:-2.039015,M:20.5576,S:0.134198},198:{L:-1.99315,M:20.9029,S:0.13362},204:{L:-1.949135,M:21.2425,S:0.133057},210:{L:-1.908831,M:21.5742,S:0.132585},216:{L:-1.87467,M:21.8959,S:0.132286},222:{L:-1.849323,M:22.2054,S:0.132249},228:{L:-1.835138,M:22.5007,S:0.132566},234:{L:-1.833401,M:22.7799,S:0.133339},240:{L:-1.843581,M:23.0414,S:0.134675}},female:{24:{L:-1.024497,M:16.388,S:0.085026},30:{L:-1.534542,M:16.0059,S:0.080932},36:{L:-2.096829,M:15.6992,S:0.078605},42:{L:-2.618733,M:15.4647,S:0.077904},48:{L:-3.018522,M:15.2985,S:0.078713},54:{L:-3.2593,M:15.1961,S:0.080904},60:{L:-3.350078,M:15.1519,S:0.0843},66:{L:-3.325522,M:15.1606,S:0.08868},72:{L:-3.225607,M:15.2169,S:0.093803},78:{L:-3.084291,M:15.3161,S:0.099427},84:{L:-2.926187,M:15.4536,S:0.105325},90:{L:-2.76731,M:15.6252,S:0.111295},96:{L:-2.617192,M:15.827,S:0.117159},102:{L:-2.480952,M:16.0552,S:0.122771},108:{L:-2.360921,M:16.3061,S:0.128014},114:{L:-2.257782,M:16.5763,S:0.132797},120:{L:-2.171296,M:16.8623,S:0.137057},126:{L:-2.100749,M:17.161,S:0.140754},132:{L:-2.045235,M:17.4691,S:0.143868},138:{L:-2.003802,M:17.7836,S:0.146399},144:{L:-1.975521,M:18.1015,S:0.148361},150:{L:-1.95952,M:18.42,S:0.149783},156:{L:-1.954978,M:18.7364,S:0.150705},162:{L:-1.9611,M:19.0481,S:0.151176},168:{L:-1.977074,M:19.3526,S:0.151256},174:{L:-2.002014,M:19.6475,S:0.15101},180:{L:-2.034893,M:19.9306,S:0.150512},186:{L:-2.07446,M:20.1998,S:0.149843},192:{L:-2.119157,M:20.4533,S:0.14909},198:{L:-2.167045,M:20.6891,S:0.148349},204:{L:-2.215738,M:20.9058,S:0.147723},210:{L:-2.262382,M:21.1016,S:0.147323},216:{L:-2.303688,M:21.2753,S:0.147269},222:{L:-2.336038,M:21.4255,S:0.147689},228:{L:-2.355678,M:21.5508,S:0.148724},234:{L:-2.35898,M:21.6501,S:0.150521},240:{L:-2.342797,M:21.7219,S:0.153241}}};

    function calcBMIPercentile(bmi, L, M, S) {
      // Z-score from LMS: Z = ((BMI/M)^L - 1) / (L * S)
      var z;
      if (Math.abs(L) < 0.001) {
        z = Math.log(bmi / M) / S;
      } else {
        z = (Math.pow(bmi / M, L) - 1) / (L * S);
      }
      // Convert Z to percentile using standard normal CDF approximation
      var p = normalCDF(z);
      return { z: z, percentile: Math.round(p * 10000) / 100 };
    }

    function normalCDF(z) {
      var a1=0.254829592, a2=-0.284496736, a3=1.421413741, a4=-1.453152027, a5=1.061405429, p=0.3275911;
      var sign = z < 0 ? -1 : 1;
      z = Math.abs(z) / Math.sqrt(2);
      var t = 1 / (1 + p * z);
      var y = 1 - (((((a5*t+a4)*t)+a3)*t+a2)*t+a1)*t*Math.exp(-z*z);
      return 0.5 * (1 + sign * y);
    }

    // ═══════════════════════════════════════════════════════════
    // CHART.JS GROWTH CURVE RENDERING
    // ═══════════════════════════════════════════════════════════

    // Inverse LMS: given Z-score, return measurement value
    function valueFromLMS(L, M, S, z) {
      if (Math.abs(L) < 0.001) return M * Math.exp(S * z);
      return M * Math.pow(1 + L * S * z, 1 / L);
    }

    // 7-line reference set: 3, 10, 25, 50, 75, 90, 97.
    // Drops 5th and 95th (they crowded the 3rd/10th and 90th/97th labels
    // on mobile without adding clinical value — 3rd/97th are the
    // abnormal-threshold lines, the inner percentiles give the trend).
    var PERCENTILE_LINES = [
      { p: 3,  z: -1.88079, color: 'rgba(220,38,38,0.9)',   dash: [6,4], width: 1.4 },  // red
      { p: 10, z: -1.28155, color: 'rgba(234,88,12,0.9)',   dash: [],    width: 1.2 },  // orange
      { p: 25, z: -0.67449, color: 'rgba(202,138,4,0.85)',  dash: [],    width: 1.1 },  // amber
      { p: 50, z: 0,        color: 'rgba(22,163,74,0.95)',  dash: [],    width: 2.4 },  // green (center)
      { p: 75, z: 0.67449,  color: 'rgba(37,99,235,0.85)',  dash: [],    width: 1.1 },  // blue
      { p: 90, z: 1.28155,  color: 'rgba(124,58,237,0.9)',  dash: [],    width: 1.2 },  // violet
      { p: 97, z: 1.88079,  color: 'rgba(219,39,119,0.9)',  dash: [6,4], width: 1.4 }   // pink
    ];

    function generatePercentileCurves(lmsTable, percentileLines) {
      var ages = Object.keys(lmsTable).map(Number).sort(function(a,b){return a-b;});
      var datasets = [];
      percentileLines.forEach(function(pl, idx) {
        var points = [];
        ages.forEach(function(age) {
          var lms = lmsTable[age];
          var val = valueFromLMS(lms.L, lms.M, lms.S, pl.z);
          if (isFinite(val) && val > 0) points.push({ x: age, y: Math.round(val * 100) / 100 });
        });
        datasets.push({
          label: pl.p + 'th',
          data: points,
          borderColor: pl.color,
          borderWidth: pl.width,
          borderDash: pl.dash,
          pointRadius: 0,
          pointHoverRadius: 0,
          fill: false,
          tension: 0.4,
          order: 10
        });
      });
      // Fill bands between symmetric percentile pairs.
      // Indexes: 3=0, 10=1, 25=2, 50=3, 75=4, 90=5, 97=6
      var fills = [
        { outer: 0, inner: 6, color: 'rgba(220,38,38,0.04)' },   // 3rd-97th (widest)
        { outer: 1, inner: 5, color: 'rgba(234,88,12,0.04)' },   // 10th-90th
        { outer: 2, inner: 4, color: 'rgba(163,163,163,0.05)' }  // 25th-75th (IQR)
      ];
      fills.forEach(function(f) {
        if (datasets[f.outer] && datasets[f.inner]) {
          datasets[f.outer].fill = { target: f.inner, above: f.color, below: f.color };
        }
      });
      return datasets;
    }

    var _chartInstances = {};

    // Chart.js plugin — labels each percentile curve at its right edge,
    // spreads labels bidirectionally so top (97/95/90) and bottom (3/5/10)
    // clusters both breathe, draws a thin leader from each label to the
    // actual curve position when nudged, then repaints the patient dot
    // ON TOP so it's never obscured by a label.
    var percentileLabelPlugin = {
      id: 'percentileLabels',
      afterDatasetsDraw: function(chart) {
        var ctx = chart.ctx;
        var font = '700 11px -apple-system,BlinkMacSystemFont,"Segoe UI",Helvetica,Arial,sans-serif';
        var MIN_GAP = 15;

        // Collect percentile-line labels with native screen positions
        var items = [];
        chart.data.datasets.forEach(function(ds, i) {
          if (!ds.label || !/^\d+th$/.test(ds.label)) return;
          var meta = chart.getDatasetMeta(i);
          if (!meta || meta.hidden || !meta.data || !meta.data.length) return;
          var last = meta.data[meta.data.length - 1];
          if (!last) return;
          items.push({ label: ds.label, color: ds.borderColor, x: last.x, nativeY: last.y, targetY: last.y });
        });
        // Top to bottom (ascending canvas Y)
        items.sort(function(a, b) { return a.nativeY - b.nativeY; });

        // Forward pass — push items DOWN when crowded by item above
        for (var k = 1; k < items.length; k++) {
          if (items[k].targetY - items[k - 1].targetY < MIN_GAP) {
            items[k].targetY = items[k - 1].targetY + MIN_GAP;
          }
        }
        // Backward pass — pull items UP when still crowded by item below
        for (var j = items.length - 2; j >= 0; j--) {
          if (items[j + 1].targetY - items[j].targetY < MIN_GAP) {
            items[j].targetY = items[j + 1].targetY - MIN_GAP;
          }
        }
        // Clamp to chart area so nothing clips top/bottom
        var area = chart.chartArea;
        if (area) {
          items.forEach(function(it) {
            if (it.targetY < area.top + 6) it.targetY = area.top + 6;
            if (it.targetY > area.bottom - 6) it.targetY = area.bottom - 6;
          });
        }

        // Draw leader + label
        items.forEach(function(it) {
          var stroke = typeof it.color === 'string' ? it.color : '#555';
          var m = stroke.match(/rgba?\((\d+),\s*(\d+),\s*(\d+)/);
          if (m) stroke = 'rgb(' + m[1] + ',' + m[2] + ',' + m[3] + ')';
          ctx.save();
          // Leader — only if the label was nudged away from its native Y
          if (Math.abs(it.targetY - it.nativeY) > 2) {
            ctx.strokeStyle = stroke;
            ctx.globalAlpha = 0.55;
            ctx.lineWidth = 0.8;
            ctx.beginPath();
            ctx.moveTo(it.x, it.nativeY);
            ctx.lineTo(it.x + 4, it.targetY);
            ctx.stroke();
            ctx.globalAlpha = 1;
          }
          // Label with white halo
          ctx.font = font;
          ctx.textAlign = 'left';
          ctx.textBaseline = 'middle';
          ctx.lineWidth = 3;
          ctx.strokeStyle = 'rgba(255,255,255,0.92)';
          ctx.strokeText(it.label, it.x + 5, it.targetY);
          ctx.fillStyle = stroke;
          ctx.fillText(it.label, it.x + 5, it.targetY);
          ctx.restore();
        });

        // Repaint the patient dot ON TOP of the labels so it's never
        // covered by a nearby percentile label.
        chart.data.datasets.forEach(function(ds, i) {
          if (ds.label !== 'Patient') return;
          var meta = chart.getDatasetMeta(i);
          if (!meta || !meta.data || !meta.data.length) return;
          var pt = meta.data[0];
          if (!pt) return;
          ctx.save();
          ctx.beginPath();
          ctx.arc(pt.x, pt.y, 5, 0, Math.PI * 2);
          ctx.fillStyle = '#2563eb';
          ctx.fill();
          ctx.lineWidth = 1.8;
          ctx.strokeStyle = '#ffffff';
          ctx.stroke();
          ctx.restore();
        });
      }
    };

    function renderGrowthChart(canvasId, containerId, lmsTable, patientX, patientY, xLabel, yLabel, extraDatasets) {
      if (typeof Chart === 'undefined') return; // Chart.js not loaded yet

      var container = document.getElementById(containerId);
      if (!container) return;
      container.classList.remove('hidden');

      if (_chartInstances[canvasId]) { _chartInstances[canvasId].destroy(); _chartInstances[canvasId] = null; }

      var datasets = generatePercentileCurves(lmsTable, PERCENTILE_LINES);

      // Patient data point — drawn on top of every curve. White ring so
      // it reads cleanly even when it lands directly on a colored line.
      datasets.push({
        label: 'Patient',
        data: [{ x: patientX, y: patientY }],
        backgroundColor: '#2563eb',
        borderColor: '#ffffff',
        borderWidth: 1.8,
        pointRadius: 5,
        pointHoverRadius: 7,
        pointStyle: 'circle',
        showLine: false,
        type: 'scatter',
        order: -1
      });

      if (extraDatasets) extraDatasets.forEach(function(d) { datasets.push(d); });

      _chartInstances[canvasId] = new Chart(document.getElementById(canvasId), {
        type: 'line',
        data: { datasets: datasets },
        plugins: [percentileLabelPlugin],
        options: {
          responsive: true,
          maintainAspectRatio: true,
          aspectRatio: 1.6,
          animation: { duration: 300 },
          // Leave ~28px of padding on the right so the percentile labels
          // ("50th", "95th", ...) drawn past the last data point are not
          // clipped by the canvas edge.
          layout: { padding: { right: 30 } },
          scales: {
            x: {
              type: 'linear',
              title: { display: true, text: xLabel, font: { size: 12, weight: 'bold' } },
              grid: { color: 'rgba(0,0,0,0.05)' }
            },
            y: {
              title: { display: true, text: yLabel, font: { size: 12, weight: 'bold' } },
              grid: { color: 'rgba(0,0,0,0.05)' }
            }
          },
          plugins: {
            legend: { display: false },
            tooltip: {
              callbacks: {
                label: function(ctx) {
                  if (ctx.dataset.label === 'Patient') return 'Patient: ' + ctx.parsed.y.toFixed(1) + ' ' + yLabel.split('(').pop().replace(')', '');
                  return ctx.dataset.label + ': ' + ctx.parsed.y.toFixed(1);
                }
              }
            }
          }
        }
      });
    }

    // Mid-parental height calculation
    function calcMidParentalHeight(motherHt, fatherHt, sex) {
      if (!motherHt || !fatherHt) return null;
      var mph = sex === 'male' ? (motherHt + fatherHt + 13) / 2 : (motherHt + fatherHt - 13) / 2;
      return { target: mph, low: mph - 8.5, high: mph + 8.5 };
    }

    // Extended BMI classification per CDC 2022
    // Uses % of 95th percentile for severe obesity staging
    function classifyBMI(percentile, bmi, lms) {
      // Calculate 95th percentile BMI from LMS
      var p95z = 1.645; // Z for 95th percentile
      var bmi95;
      if (Math.abs(lms.L) < 0.001) bmi95 = lms.M * Math.exp(lms.S * p95z);
      else bmi95 = lms.M * Math.pow(1 + lms.L * lms.S * p95z, 1 / lms.L);

      var pctOf95 = (bmi / bmi95) * 100;

      if (percentile >= 95) {
        if (pctOf95 >= 140) return { text: 'Class 3 Severe Obesity', color: '#7f1d1d', bg: '#fecaca', pctOf95: pctOf95, bmi95: bmi95 };
        if (pctOf95 >= 120) return { text: 'Class 2 Severe Obesity', color: '#dc2626', bg: '#fee2e2', pctOf95: pctOf95, bmi95: bmi95 };
        return { text: 'Obese (Class 1)', color: '#ef4444', bg: '#fee2e2', pctOf95: pctOf95, bmi95: bmi95 };
      }
      if (percentile >= 85) return { text: 'Overweight', color: '#f97316', bg: '#ffedd5', pctOf95: pctOf95, bmi95: bmi95 };
      if (percentile >= 5)  return { text: 'Healthy Weight', color: '#10b981', bg: '#d1fae5', pctOf95: pctOf95, bmi95: bmi95 };
      return { text: 'Underweight', color: '#f59e0b', bg: '#fef3c7', pctOf95: pctOf95, bmi95: bmi95 };
    }

    document.getElementById('btn-calc-bmi').addEventListener('click', function() {
      var ageYr = parseFloat(document.getElementById('bmi-age-yr').value) || 0;
      var ageMo = parseInt(document.getElementById('bmi-age-mo').value) || 0;
      var age = ageYr + ageMo / 12;
      var sex = document.getElementById('bmi-sex').value;
      var weight = parseFloat(document.getElementById('bmi-weight').value);
      var height = parseFloat(document.getElementById('bmi-height').value);

      if (!age || !sex || !weight || !height) { showToast('Fill in all fields', 'error'); return; }
      if (age < 2 || age > 20) { showToast('Age must be 2-20 years', 'error'); return; }

      var bmi = weight / Math.pow(height / 100, 2);
      var ageMonths = Math.round(age * 12);
      if (ageMonths < 24) ageMonths = 24;
      if (ageMonths > 240) ageMonths = 240;
      var lms = interpolateLMS(bmiLMS[sex], ageMonths);
      if (!lms) { showToast('Invalid age/sex', 'error'); return; }

      var result = calcBMIPercentile(bmi, lms.L, lms.M, lms.S);
      var cl = classifyBMI(result.percentile, bmi, lms);

      var extendedInfo = '';
      if (result.percentile >= 85) {
        extendedInfo = '<div class="calc-result-item"><div class="calc-result-label">% of 95th</div><div class="calc-result-value" style="font-size:16px;">' + cl.pctOf95.toFixed(0) + '%</div><div class="calc-result-sub">95th = ' + cl.bmi95.toFixed(1) + ' kg/m&sup2;</div></div>';
      }

      var resultDiv = document.getElementById('bmi-result');
      resultDiv.classList.remove('hidden');
      resultDiv.innerHTML =
        '<div class="calc-result-header" style="background:' + cl.bg + ';border-color:' + cl.color + ';">' +
          '<div style="font-size:18px;font-weight:700;color:' + cl.color + ';">' + cl.text + '</div>' +
          '<div style="font-size:13px;color:var(--g600);margin-top:4px;">BMI ' + bmi.toFixed(1) + ' kg/m&sup2; &mdash; ' + result.percentile + 'th percentile' + (cl.pctOf95 && result.percentile >= 95 ? ' (' + cl.pctOf95.toFixed(0) + '% of 95th)' : '') + '</div>' +
        '</div>' +
        '<div class="calc-result-grid">' +
          '<div class="calc-result-item"><div class="calc-result-label">BMI</div><div class="calc-result-value">' + bmi.toFixed(1) + '</div><div class="calc-result-sub">kg/m&sup2;</div></div>' +
          '<div class="calc-result-item"><div class="calc-result-label">Percentile</div><div class="calc-result-value">' + result.percentile + '<span style="font-size:12px;">th</span></div></div>' +
          '<div class="calc-result-item"><div class="calc-result-label">Z-Score</div><div class="calc-result-value" style="font-size:16px;">' + result.z.toFixed(2) + '</div></div>' +
          extendedInfo +
        '</div>';
      var bmiYears = {}; Object.keys(bmiLMS[sex]).forEach(function(k) { bmiYears[+(k/12).toFixed(1)] = bmiLMS[sex][k]; });
      renderGrowthChart('bmi-chart-canvas', 'bmi-chart-container', bmiYears, +(ageMonths/12).toFixed(1), bmi, 'Age (years)', 'BMI (kg/m2)');
    });

    document.getElementById('btn-clear-bmi').addEventListener('click', function() {
      ['bmi-age-yr', 'bmi-sex', 'bmi-weight', 'bmi-height'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      document.getElementById('bmi-result').classList.add('hidden');
    });

    // ═══════════════════════════════════════════════════════════
    // BODY SURFACE AREA — Mosteller
    // ═══════════════════════════════════════════════════════════

    document.getElementById('btn-calc-bsa').addEventListener('click', function() {
      var weight = parseFloat(document.getElementById('bsa-weight').value);
      var height = parseFloat(document.getElementById('bsa-height').value);
      if (!weight || !height) { showToast('Enter weight and height', 'error'); return; }

      var bsa = Math.sqrt(height * weight / 3600);
      var resultDiv = document.getElementById('bsa-result');
      resultDiv.classList.remove('hidden');
      resultDiv.innerHTML =
        '<div class="calc-result-header" style="background:#e0f2fe;border-color:#0ea5e9;">' +
          '<div style="font-size:18px;font-weight:700;color:#0369a1;">BSA: ' + bsa.toFixed(3) + ' m&sup2;</div>' +
          '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + weight + ' kg, ' + height + ' cm (Mosteller formula)</div>' +
        '</div>';
    });

    document.getElementById('btn-clear-bsa').addEventListener('click', function() {
      ['bsa-weight', 'bsa-height'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      document.getElementById('bsa-result').classList.add('hidden');
    });

    // ═══════════════════════════════════════════════════════════
    // WEIGHT-BASED DOSING
    // ═══════════════════════════════════════════════════════════

    document.getElementById('btn-calc-dose').addEventListener('click', function() {
      var weight = parseFloat(document.getElementById('dose-weight').value);
      var dosePerKg = parseFloat(document.getElementById('dose-per-kg').value);
      var freq = parseInt(document.getElementById('dose-freq').value);
      var maxDose = parseFloat(document.getElementById('dose-max').value) || 0;
      var conc = parseFloat(document.getElementById('dose-conc').value) || 0;

      if (!weight || !dosePerKg) { showToast('Enter weight and dose', 'error'); return; }

      var singleDose = weight * dosePerKg;
      var capped = false;
      if (maxDose > 0 && singleDose > maxDose) { singleDose = maxDose; capped = true; }
      var dailyDose = singleDose * freq;

      var rows = '<div class="calc-result-item"><div class="calc-result-label">Single Dose</div><div class="calc-result-value">' + singleDose.toFixed(1) + ' <span style="font-size:12px;">mg</span></div>'
        + (capped ? '<div class="calc-result-sub" style="color:var(--red);">Capped at max ' + maxDose + ' mg</div>' : '') + '</div>'
        + '<div class="calc-result-item"><div class="calc-result-label">Daily Total</div><div class="calc-result-value">' + dailyDose.toFixed(1) + ' <span style="font-size:12px;">mg/day</span></div>'
        + '<div class="calc-result-sub">' + singleDose.toFixed(1) + ' mg x ' + freq + '/day</div></div>';

      if (conc > 0) {
        var vol = singleDose / conc;
        rows += '<div class="calc-result-item"><div class="calc-result-label">Volume per Dose</div><div class="calc-result-value">' + vol.toFixed(1) + ' <span style="font-size:12px;">mL</span></div>'
          + '<div class="calc-result-sub">at ' + conc + ' mg/mL</div></div>';
      }

      var resultDiv = document.getElementById('dose-result');
      resultDiv.classList.remove('hidden');
      resultDiv.innerHTML =
        '<div class="calc-result-header" style="background:#ede9fe;border-color:#7c3aed;">' +
          '<div style="font-size:18px;font-weight:700;color:#6d28d9;">' + singleDose.toFixed(1) + ' mg per dose</div>' +
          '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + weight + ' kg x ' + dosePerKg + ' mg/kg' + (capped ? ' (max ' + maxDose + ' mg)' : '') + '</div>' +
        '</div>' +
        '<div class="calc-result-grid">' + rows + '</div>' +
        '<p style="font-size:11px;color:var(--g400);margin:12px 0 0;">Always verify dosing against your formulary and institutional guidelines.</p>';
    });

    document.getElementById('btn-clear-dose').addEventListener('click', function() {
      ['dose-weight', 'dose-per-kg', 'dose-max', 'dose-conc'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      document.getElementById('dose-freq').value = '1';
      document.getElementById('dose-result').classList.add('hidden');
    });

    // ═══════════════════════════════════════════════════════════
    // GROWTH CHARTS — WHO 0-2y / CDC 2-20y + Fenton Preterm
    // ═══════════════════════════════════════════════════════════

    var currentGrowthType = 'wfa';

    // WHO Weight-for-Age 0-60mo (monthly, from WHO Anthro daily LMS)
    var wfaLMS = {male:{0:{L:0.3487,M:3.3464,S:0.14602},1:{L:0.2303,M:4.4525,S:0.13413},2:{L:0.1969,M:5.5714,S:0.12382},3:{L:0.174,M:6.369,S:0.11732},4:{L:0.1551,M:7.0069,S:0.11313},5:{L:0.1396,M:7.5077,S:0.11081},6:{L:0.1256,M:7.9389,S:0.10957},7:{L:0.1134,M:8.2963,S:0.10902},8:{L:0.1019,M:8.62,S:0.10882},9:{L:0.0917,M:8.9019,S:0.10881},10:{L:0.0821,M:9.1618,S:0.1089},11:{L:0.0729,M:9.4136,S:0.10906},12:{L:0.0645,M:9.646,S:0.10925},13:{L:0.0563,M:9.8772,S:0.10949},14:{L:0.0487,M:10.0944,S:0.10976},15:{L:0.0412,M:10.3139,S:0.11008},16:{L:0.0343,M:10.5228,S:0.11041},17:{L:0.0276,M:10.7289,S:0.11078},18:{L:0.021,M:10.9393,S:0.1112},19:{L:0.0149,M:11.1409,S:0.11163},20:{L:0.0087,M:11.3478,S:0.11212},21:{L:0.0029,M:11.5474,S:0.11261},22:{L:-0.0029,M:11.7528,S:0.11315},23:{L:-0.0083,M:11.951,S:0.11369},24:{L:-0.0136,M:12.1482,S:0.11425},25:{L:-0.0189,M:12.3506,S:0.11485},26:{L:-0.0239,M:12.5442,S:0.11544},27:{L:-0.0289,M:12.7413,S:0.11604},28:{L:-0.0337,M:12.9288,S:0.11663},29:{L:-0.0385,M:13.1188,S:0.11723},30:{L:-0.0431,M:13.2993,S:0.11781},31:{L:-0.0477,M:13.4824,S:0.1184},32:{L:-0.052,M:13.6567,S:0.11896},33:{L:-0.0563,M:13.8285,S:0.11952},34:{L:-0.0607,M:14.0038,S:0.12008},35:{L:-0.0648,M:14.1719,S:0.12062},36:{L:-0.0689,M:14.3443,S:0.12116},37:{L:-0.0729,M:14.5102,S:0.12168},38:{L:-0.0769,M:14.6811,S:0.12221},39:{L:-0.0808,M:14.8462,S:0.12271},40:{L:-0.0846,M:15.0167,S:0.12323},41:{L:-0.0883,M:15.1816,S:0.12373},42:{L:-0.092,M:15.3465,S:0.12424},43:{L:-0.0957,M:15.5168,S:0.12478},44:{L:-0.0992,M:15.6815,S:0.12531},45:{L:-0.1028,M:15.8514,S:0.12587},46:{L:-0.1063,M:16.0156,S:0.12642},47:{L:-0.1098,M:16.1851,S:0.12701},48:{L:-0.1131,M:16.3489,S:0.12759},49:{L:-0.1164,M:16.5126,S:0.12818},50:{L:-0.1198,M:16.6818,S:0.12881},51:{L:-0.123,M:16.8454,S:0.12942},52:{L:-0.1263,M:17.0145,S:0.13006},53:{L:-0.1294,M:17.1782,S:0.13068},54:{L:-0.1326,M:17.3473,S:0.13133},55:{L:-0.1356,M:17.5107,S:0.13196},56:{L:-0.1387,M:17.674,S:0.1326},57:{L:-0.1417,M:17.8425,S:0.13325},58:{L:-0.1447,M:18.0053,S:0.13389},59:{L:-0.1477,M:18.1732,S:0.13454},60:{L:-0.1506,M:18.3352,S:0.13517}},female:{0:{L:0.3809,M:3.2322,S:0.14171},1:{L:0.1727,M:4.1716,S:0.13738},2:{L:0.0959,M:5.1315,S:0.12998},3:{L:0.0407,M:5.8393,S:0.12622},4:{L:-0.0053,M:6.428,S:0.12401},5:{L:-0.0428,M:6.8959,S:0.12274},6:{L:-0.0759,M:7.3016,S:0.12204},7:{L:-0.1039,M:7.6416,S:0.12178},8:{L:-0.1292,M:7.9534,S:0.12181},9:{L:-0.1507,M:8.2259,S:0.12199},10:{L:-0.1698,M:8.4769,S:0.12222},11:{L:-0.1873,M:8.7207,S:0.12247},12:{L:-0.2022,M:8.9462,S:0.12267},13:{L:-0.216,M:9.1722,S:0.12283},14:{L:-0.2277,M:9.3861,S:0.12294},15:{L:-0.2385,M:9.6038,S:0.12299},16:{L:-0.2478,M:9.8124,S:0.12303},17:{L:-0.2561,M:10.0196,S:0.12305},18:{L:-0.2637,M:10.2324,S:0.12309},19:{L:-0.2702,M:10.4372,S:0.12315},20:{L:-0.2763,M:10.6481,S:0.12324},21:{L:-0.2814,M:10.8521,S:0.12335},22:{L:-0.2862,M:11.0633,S:0.12351},23:{L:-0.2903,M:11.2684,S:0.12369},24:{L:-0.294,M:11.4741,S:0.12389},25:{L:-0.2975,M:11.6868,S:0.12414},26:{L:-0.3005,M:11.8922,S:0.12441},27:{L:-0.3033,M:12.1028,S:0.12472},28:{L:-0.3057,M:12.3042,S:0.12506},29:{L:-0.308,M:12.5093,S:0.12545},30:{L:-0.3101,M:12.7047,S:0.12587},31:{L:-0.312,M:12.9033,S:0.12634},32:{L:-0.3138,M:13.093,S:0.12683},33:{L:-0.3155,M:13.2809,S:0.12736},34:{L:-0.3171,M:13.4739,S:0.12794},35:{L:-0.3186,M:13.6599,S:0.12854},36:{L:-0.3201,M:13.8518,S:0.1292},37:{L:-0.3216,M:14.0373,S:0.12987},38:{L:-0.323,M:14.2288,S:0.1306},39:{L:-0.3243,M:14.4136,S:0.13134},40:{L:-0.3257,M:14.6041,S:0.13214},41:{L:-0.327,M:14.7877,S:0.13294},42:{L:-0.3283,M:14.9704,S:0.13375},43:{L:-0.3296,M:15.1584,S:0.13461},44:{L:-0.3309,M:15.3395,S:0.13544},45:{L:-0.3322,M:15.5259,S:0.13631},46:{L:-0.3335,M:15.7056,S:0.13715},47:{L:-0.3348,M:15.8908,S:0.13801},48:{L:-0.3361,M:16.0697,S:0.13884},49:{L:-0.3374,M:16.2485,S:0.13967},50:{L:-0.3387,M:16.433,S:0.14051},51:{L:-0.34,M:16.6114,S:0.14132},52:{L:-0.3414,M:16.7957,S:0.14214},53:{L:-0.3427,M:16.9737,S:0.14292},54:{L:-0.344,M:17.1573,S:0.14372},55:{L:-0.3453,M:17.3344,S:0.14448},56:{L:-0.3466,M:17.5107,S:0.14524},57:{L:-0.3479,M:17.692,S:0.146},58:{L:-0.3492,M:17.8664,S:0.14674},59:{L:-0.3505,M:18.0456,S:0.14749},60:{L:-0.3518,M:18.2179,S:0.14821}}};

    // CDC Weight-for-Age 24-240mo (every 6 months)
    var cdcWfaLMS = {male:{24:{L:-0.216501,M:12.7415,S:0.108166},30:{L:-0.397568,M:13.5609,S:0.109378},36:{L:-0.62132,M:14.4026,S:0.111875},42:{L:-0.804515,M:15.3194,S:0.115493},48:{L:-0.915242,M:16.3168,S:0.119955},54:{L:-0.969633,M:17.3791,S:0.124879},60:{L:-1.000454,M:18.4859,S:0.129879},66:{L:-1.035044,M:19.6214,S:0.134676},72:{L:-1.087471,M:20.7777,S:0.139143},78:{L:-1.158132,M:21.9564,S:0.14331},84:{L:-1.236497,M:23.1674,S:0.147337},90:{L:-1.306268,M:24.4265,S:0.151472},96:{L:-1.351813,M:25.7526,S:0.155974},102:{L:-1.363458,M:27.1649,S:0.161026},108:{L:-1.339405,M:28.6813,S:0.166659},114:{L:-1.284375,M:30.3177,S:0.172729},120:{L:-1.206688,M:32.088,S:0.178929},126:{L:-1.115543,M:34.0036,S:0.184847},132:{L:-1.019277,M:36.0726,S:0.19003},138:{L:-0.92467,M:38.2978,S:0.194053},144:{L:-0.836962,M:40.6744,S:0.196592},150:{L:-0.760274,M:43.1883,S:0.197464},156:{L:-0.698166,M:45.8134,S:0.196662},162:{L:-0.654143,M:48.5111,S:0.194344},168:{L:-0.631877,M:51.231,S:0.190808},174:{L:-0.634919,M:53.9126,S:0.186442},180:{L:-0.665609,M:56.491,S:0.181666},186:{L:-0.723218,M:58.9029,S:0.176887},192:{L:-0.801993,M:61.0954,S:0.172459},198:{L:-0.890436,M:63.0323,S:0.168655},204:{L:-0.973245,M:64.6996,S:0.16564},210:{L:-1.035402,M:66.1075,S:0.163439},216:{L:-1.066224,M:67.2899,S:0.161923},222:{L:-1.061342,M:68.3,S:0.16087},228:{L:-1.023292,M:69.1947,S:0.160138},234:{L:-0.964377,M:69.9987,S:0.160007},240:{L:-0.916488,M:70.5976,S:0.161477}},female:{24:{L:-0.752207,M:12.1346,S:0.10774},30:{L:-0.914719,M:13.0436,S:0.113023},36:{L:-1.024471,M:13.9411,S:0.119492},42:{L:-1.107022,M:14.8812,S:0.125973},48:{L:-1.17703,M:15.8782,S:0.131802},54:{L:-1.238331,M:16.9283,S:0.136811},60:{L:-1.287692,M:18.0231,S:0.141191},66:{L:-1.318993,M:19.1583,S:0.145317},72:{L:-1.326764,M:20.3364,S:0.14959},78:{L:-1.308487,M:21.5675,S:0.154326},84:{L:-1.265549,M:22.868,S:0.159693},90:{L:-1.202884,M:24.2579,S:0.165689},96:{L:-1.127684,M:25.757,S:0.172147},102:{L:-1.047847,M:27.382,S:0.178774},108:{L:-0.970686,M:29.1429,S:0.185201},114:{L:-0.902198,M:31.0403,S:0.191041},120:{L:-0.846873,M:33.0639,S:0.195947},126:{L:-0.807873,M:35.1918,S:0.199648},132:{L:-0.787374,M:37.3909,S:0.201971},138:{L:-0.786904,M:39.6191,S:0.202848},144:{L:-0.8076,M:41.828,S:0.202299},150:{L:-0.850307,M:43.9661,S:0.200419},156:{L:-0.915514,M:45.9837,S:0.197363},162:{L:-1.003051,M:47.8366,S:0.19333},168:{L:-1.111606,M:49.4908,S:0.18856},174:{L:-1.238005,M:50.9254,S:0.183328},180:{L:-1.376478,M:52.1357,S:0.177947},186:{L:-1.518156,M:53.1333,S:0.172761},192:{L:-1.651248,M:53.9454,S:0.168125},198:{L:-1.762241,M:54.6122,S:0.164368},204:{L:-1.838092,M:55.1822,S:0.161753},210:{L:-1.868977,M:55.7062,S:0.160423},216:{L:-1.850946,M:56.2297,S:0.16037},222:{L:-1.787979,M:56.7803,S:0.161399},228:{L:-1.693267,M:57.3518,S:0.163138},234:{L:-1.589533,M:57.8833,S:0.165088},240:{L:-1.513362,M:58.219,S:0.166645}}};

    // WHO Length/Height-for-Age 0-60mo (monthly)
    var lfaLMS = {male:{0:{L:1.0,M:49.8842,S:0.03795},1:{L:1.0,M:54.6645,S:0.03559},2:{L:1.0,M:58.4384,S:0.03423},3:{L:1.0,M:61.4013,S:0.03329},4:{L:1.0,M:63.9041,S:0.03257},5:{L:1.0,M:65.8912,S:0.03204},6:{L:1.0,M:67.6435,S:0.03165},7:{L:1.0,M:69.1615,S:0.03139},8:{L:1.0,M:70.6224,S:0.03124},9:{L:1.0,M:71.9714,S:0.03117},10:{L:1.0,M:73.2653,S:0.03118},11:{L:1.0,M:74.5464,S:0.03125},12:{L:1.0,M:75.7391,S:0.03137},13:{L:1.0,M:76.9304,S:0.03154},14:{L:1.0,M:78.0451,S:0.03174},15:{L:1.0,M:79.1613,S:0.03197},16:{L:1.0,M:80.2113,S:0.03222},17:{L:1.0,M:81.234,S:0.03249},18:{L:1.0,M:82.2628,S:0.03279},19:{L:1.0,M:83.2318,S:0.0331},20:{L:1.0,M:84.2074,S:0.03342},21:{L:1.0,M:85.1291,S:0.03375},22:{L:1.0,M:86.0589,S:0.0341},23:{L:1.0,M:86.9392,S:0.03445},24:{L:1.0,M:87.8018,S:0.03479},25:{L:1.0,M:87.9737,S:0.03542},26:{L:1.0,M:88.7964,S:0.03576},27:{L:1.0,M:89.6247,S:0.0361},28:{L:1.0,M:90.4056,S:0.03642},29:{L:1.0,M:91.1906,S:0.03674},30:{L:1.0,M:91.9297,S:0.03704},31:{L:1.0,M:92.6735,S:0.03733},32:{L:1.0,M:93.3753,S:0.03761},33:{L:1.0,M:94.0612,S:0.03787},34:{L:1.0,M:94.7559,S:0.03812},35:{L:1.0,M:95.4168,S:0.03836},36:{L:1.0,M:96.0889,S:0.03858},37:{L:1.0,M:96.7298,S:0.03879},38:{L:1.0,M:97.3827,S:0.039},39:{L:1.0,M:98.006,S:0.03919},40:{L:1.0,M:98.6412,S:0.03937},41:{L:1.0,M:99.2471,S:0.03954},42:{L:1.0,M:99.8441,S:0.0397},43:{L:1.0,M:100.4522,S:0.03986},44:{L:1.0,M:101.0326,S:0.04002},45:{L:1.0,M:101.6246,S:0.04017},46:{L:1.0,M:102.191,S:0.04031},47:{L:1.0,M:102.7706,S:0.04045},48:{L:1.0,M:103.3273,S:0.04059},49:{L:1.0,M:103.8806,S:0.04073},50:{L:1.0,M:104.4496,S:0.04086},51:{L:1.0,M:104.9984,S:0.041},52:{L:1.0,M:105.5641,S:0.04113},53:{L:1.0,M:106.1104,S:0.04126},54:{L:1.0,M:106.6736,S:0.04139},55:{L:1.0,M:107.2176,S:0.04152},56:{L:1.0,M:107.7607,S:0.04165},57:{L:1.0,M:108.3209,S:0.04177},58:{L:1.0,M:108.8621,S:0.0419},59:{L:1.0,M:109.4203,S:0.04202},60:{L:1.0,M:109.9593,S:0.04214}},female:{0:{L:1.0,M:49.1477,S:0.0379},1:{L:1.0,M:53.6326,S:0.03641},2:{L:1.0,M:57.0796,S:0.03568},3:{L:1.0,M:59.7773,S:0.0352},4:{L:1.0,M:62.1071,S:0.03486},5:{L:1.0,M:64.019,S:0.03463},6:{L:1.0,M:65.751,S:0.03448},7:{L:1.0,M:67.2842,S:0.03441},8:{L:1.0,M:68.7732,S:0.0344},9:{L:1.0,M:70.1463,S:0.03444},10:{L:1.0,M:71.4656,S:0.03452},11:{L:1.0,M:72.7788,S:0.03464},12:{L:1.0,M:74.0049,S:0.03479},13:{L:1.0,M:75.2297,S:0.03496},14:{L:1.0,M:76.377,S:0.03514},15:{L:1.0,M:77.5258,S:0.03534},16:{L:1.0,M:78.6055,S:0.03555},17:{L:1.0,M:79.6559,S:0.03576},18:{L:1.0,M:80.7121,S:0.03598},19:{L:1.0,M:81.708,S:0.0362},20:{L:1.0,M:82.7116,S:0.03643},21:{L:1.0,M:83.6595,S:0.03665},22:{L:1.0,M:84.6154,S:0.03689},23:{L:1.0,M:85.5184,S:0.03711},24:{L:1.0,M:86.4008,S:0.03733},25:{L:1.0,M:86.5922,S:0.03786},26:{L:1.0,M:87.4358,S:0.03808},27:{L:1.0,M:88.2881,S:0.0383},28:{L:1.0,M:89.0938,S:0.03851},29:{L:1.0,M:89.9072,S:0.03872},30:{L:1.0,M:90.6765,S:0.03893},31:{L:1.0,M:91.4539,S:0.03913},32:{L:1.0,M:92.1906,S:0.03933},33:{L:1.0,M:92.9135,S:0.03952},34:{L:1.0,M:93.6473,S:0.03971},35:{L:1.0,M:94.346,S:0.03989},36:{L:1.0,M:95.0572,S:0.04007},37:{L:1.0,M:95.7356,S:0.04024},38:{L:1.0,M:96.427,S:0.04041},39:{L:1.0,M:97.0871,S:0.04057},40:{L:1.0,M:97.7601,S:0.04074},41:{L:1.0,M:98.4028,S:0.04089},42:{L:1.0,M:99.0369,S:0.04105},43:{L:1.0,M:99.6834,S:0.0412},44:{L:1.0,M:100.3007,S:0.04135},45:{L:1.0,M:100.9301,S:0.0415},46:{L:1.0,M:101.5312,S:0.04164},47:{L:1.0,M:102.1446,S:0.04179},48:{L:1.0,M:102.7312,S:0.04193},49:{L:1.0,M:103.3113,S:0.04206},50:{L:1.0,M:103.9045,S:0.0422},51:{L:1.0,M:104.4727,S:0.04233},52:{L:1.0,M:105.0541,S:0.04247},53:{L:1.0,M:105.6114,S:0.04259},54:{L:1.0,M:106.1817,S:0.04272},55:{L:1.0,M:106.7284,S:0.04285},56:{L:1.0,M:107.2698,S:0.04297},57:{L:1.0,M:107.8238,S:0.0431},58:{L:1.0,M:108.3547,S:0.04322},59:{L:1.0,M:108.8981,S:0.04335},60:{L:1.0,M:109.4189,S:0.04346}}};

    // CDC Stature-for-Age 24-240mo (every 6 months)
    var cdcLfaLMS = {male:{24:{L:1.007208,M:86.8616,S:0.040396},30:{L:0.174489,M:91.3324,S:0.040965},36:{L:-0.390918,M:95.2736,S:0.040534},42:{L:0.32653,M:99.0025,S:0.040848},48:{L:0.827637,M:102.5105,S:0.041344},54:{L:1.133652,M:105.8813,S:0.041956},60:{L:1.266367,M:109.1751,S:0.042593},66:{L:1.255402,M:112.4296,S:0.043181},72:{L:1.137443,M:115.6609,S:0.043673},78:{L:0.954853,M:118.8668,S:0.044069},84:{L:0.753244,M:122.0305,S:0.044403},90:{L:0.575908,M:125.1259,S:0.044736},96:{L:0.455268,M:128.1237,S:0.045127},102:{L:0.404778,M:130.9983,S:0.045618},108:{L:0.415687,M:133.7345,S:0.046217},114:{L:0.461031,M:136.3343,S:0.046897},120:{L:0.505564,M:138.8234,S:0.04761},126:{L:0.518588,M:141.2582,S:0.048304},132:{L:0.487939,M:143.7304,S:0.048938},138:{L:0.434576,M:146.3665,S:0.049489},144:{L:0.420919,M:149.3088,S:0.049948},150:{L:0.531952,M:152.6624,S:0.050273},156:{L:0.81624,M:156.4099,S:0.050333},162:{L:1.232769,M:160.3493,S:0.049927},168:{L:1.670433,M:164.1418,S:0.048945},174:{L:2.016782,M:167.4641,S:0.047507},180:{L:2.20518,M:170.1393,S:0.04589},186:{L:2.225326,M:172.1563,S:0.044363},192:{L:2.113023,M:173.6101,S:0.043086},198:{L:1.927321,M:174.631,S:0.042107},204:{L:1.724738,M:175.341,S:0.041408},210:{L:1.543253,M:175.836,S:0.040938},216:{L:1.399999,M:176.185,S:0.040644},222:{L:1.297149,M:176.4352,S:0.040474},228:{L:1.229163,M:176.6179,S:0.040391},234:{L:1.18802,M:176.7538,S:0.040364},240:{L:1.167279,M:176.8492,S:0.04037}},female:{24:{L:1.051273,M:85.3973,S:0.04086},30:{L:0.814544,M:90.3334,S:0.041754},36:{L:0.541981,M:94.2134,S:0.042018},42:{L:0.377878,M:97.6485,S:0.042622},48:{L:0.225706,M:101.0339,S:0.04326},54:{L:0.075699,M:104.4635,S:0.043817},60:{L:-0.05773,M:107.9566,S:0.044277},66:{L:-0.159198,M:111.4876,S:0.044653},72:{L:-0.219069,M:115.0055,S:0.044964},78:{L:-0.234772,M:118.4496,S:0.045226},84:{L:-0.210211,M:121.7617,S:0.045461},90:{L:-0.154357,M:124.8956,S:0.045694},96:{L:-0.079283,M:127.8263,S:0.045968},102:{L:0.002744,M:130.5574,S:0.04634},108:{L:0.084148,M:133.1304,S:0.046884},114:{L:0.169805,M:135.6342,S:0.04767},120:{L:0.284749,M:138.2112,S:0.048705},126:{L:0.46918,M:141.0397,S:0.049812},132:{L:0.74429,M:144.2609,S:0.050524},138:{L:1.062475,M:147.8424,S:0.050208},144:{L:1.303045,M:151.4866,S:0.048599},150:{L:1.358163,M:154.7555,S:0.046198},156:{L:1.242968,M:157.3437,S:0.043859},162:{L:1.076971,M:159.2075,S:0.042114},168:{L:0.956572,M:160.4777,S:0.041022},174:{L:0.902452,M:161.3268,S:0.040409},180:{L:0.89557,M:161.898,S:0.040084},186:{L:0.913398,M:162.2908,S:0.039913},192:{L:0.941146,M:162.569,S:0.039821},198:{L:0.971038,M:162.7719,S:0.039767},204:{L:0.999506,M:162.9238,S:0.039732},210:{L:1.025143,M:163.0402,S:0.039707},216:{L:1.047571,M:163.1308,S:0.039687},222:{L:1.066873,M:163.2022,S:0.039671},228:{L:1.083315,M:163.259,S:0.039657},234:{L:1.097229,M:163.3045,S:0.039646},240:{L:1.108046,M:163.3383,S:0.039636}}};

    // WHO Head Circumference 0-60mo (monthly)
    var hcfaLMS = {male:{0:{L:1.0,M:34.4618,S:0.03686},1:{L:1.0,M:37.2435,S:0.03135},2:{L:1.0,M:39.1349,S:0.02997},3:{L:1.0,M:40.5008,S:0.02918},4:{L:1.0,M:41.6401,S:0.02868},5:{L:1.0,M:42.5524,S:0.02837},6:{L:1.0,M:43.3393,S:0.02817},7:{L:1.0,M:43.9791,S:0.02804},8:{L:1.0,M:44.5384,S:0.02796},9:{L:1.0,M:45.0007,S:0.02792},10:{L:1.0,M:45.4004,S:0.0279},11:{L:1.0,M:45.7593,S:0.02789},12:{L:1.0,M:46.0637,S:0.02789},13:{L:1.0,M:46.3421,S:0.02789},14:{L:1.0,M:46.5834,S:0.02791},15:{L:1.0,M:46.809,S:0.02792},16:{L:1.0,M:47.0088,S:0.02795},17:{L:1.0,M:47.1936,S:0.02797},18:{L:1.0,M:47.3718,S:0.028},19:{L:1.0,M:47.5341,S:0.02803},20:{L:1.0,M:47.6931,S:0.02806},21:{L:1.0,M:47.8399,S:0.0281},22:{L:1.0,M:47.985,S:0.02814},23:{L:1.0,M:48.1198,S:0.02817},24:{L:1.0,M:48.2494,S:0.02821},25:{L:1.0,M:48.378,S:0.02825},26:{L:1.0,M:48.4974,S:0.0283},27:{L:1.0,M:48.6158,S:0.02834},28:{L:1.0,M:48.7255,S:0.02838},29:{L:1.0,M:48.8341,S:0.02843},30:{L:1.0,M:48.9347,S:0.02847},31:{L:1.0,M:49.0341,S:0.02851},32:{L:1.0,M:49.126,S:0.02855},33:{L:1.0,M:49.214,S:0.02859},34:{L:1.0,M:49.3011,S:0.02863},35:{L:1.0,M:49.3818,S:0.02867},36:{L:1.0,M:49.4619,S:0.02871},37:{L:1.0,M:49.5362,S:0.02875},38:{L:1.0,M:49.6101,S:0.02878},39:{L:1.0,M:49.679,S:0.02882},40:{L:1.0,M:49.7476,S:0.02886},41:{L:1.0,M:49.8117,S:0.02889},42:{L:1.0,M:49.8737,S:0.02893},43:{L:1.0,M:49.9357,S:0.02896},44:{L:1.0,M:49.9938,S:0.02899},45:{L:1.0,M:50.0518,S:0.02903},46:{L:1.0,M:50.1062,S:0.02906},47:{L:1.0,M:50.1606,S:0.02909},48:{L:1.0,M:50.2115,S:0.02912},49:{L:1.0,M:50.261,S:0.02915},50:{L:1.0,M:50.3107,S:0.02918},51:{L:1.0,M:50.3573,S:0.02921},52:{L:1.0,M:50.4043,S:0.02924},53:{L:1.0,M:50.4485,S:0.02927},54:{L:1.0,M:50.4931,S:0.0293},55:{L:1.0,M:50.5353,S:0.02932},56:{L:1.0,M:50.5766,S:0.02935},57:{L:1.0,M:50.6184,S:0.02938},58:{L:1.0,M:50.6582,S:0.0294},59:{L:1.0,M:50.6986,S:0.02943},60:{L:1.0,M:50.7372,S:0.02945}},female:{0:{L:1.0,M:33.8787,S:0.03496},1:{L:1.0,M:36.5163,S:0.03211},2:{L:1.0,M:38.258,S:0.03168},3:{L:1.0,M:39.521,S:0.0314},4:{L:1.0,M:40.5895,S:0.03119},5:{L:1.0,M:41.454,S:0.03102},6:{L:1.0,M:42.2079,S:0.03087},7:{L:1.0,M:42.8278,S:0.03075},8:{L:1.0,M:43.3753,S:0.03063},9:{L:1.0,M:43.8309,S:0.03053},10:{L:1.0,M:44.2273,S:0.03044},11:{L:1.0,M:44.5865,S:0.03035},12:{L:1.0,M:44.894,S:0.03027},13:{L:1.0,M:45.1779,S:0.03019},14:{L:1.0,M:45.4255,S:0.03012},15:{L:1.0,M:45.6582,S:0.03005},16:{L:1.0,M:45.865,S:0.02999},17:{L:1.0,M:46.0571,S:0.02993},18:{L:1.0,M:46.2431,S:0.02987},19:{L:1.0,M:46.4135,S:0.02982},20:{L:1.0,M:46.5814,S:0.02977},21:{L:1.0,M:46.7375,S:0.02972},22:{L:1.0,M:46.8931,S:0.02967},23:{L:1.0,M:47.0388,S:0.02962},24:{L:1.0,M:47.1799,S:0.02958},25:{L:1.0,M:47.3207,S:0.02953},26:{L:1.0,M:47.452,S:0.02949},27:{L:1.0,M:47.5825,S:0.02945},28:{L:1.0,M:47.7035,S:0.02941},29:{L:1.0,M:47.8231,S:0.02937},30:{L:1.0,M:47.9336,S:0.02933},31:{L:1.0,M:48.0425,S:0.02929},32:{L:1.0,M:48.1432,S:0.02926},33:{L:1.0,M:48.2395,S:0.02922},34:{L:1.0,M:48.3347,S:0.02919},35:{L:1.0,M:48.423,S:0.02916},36:{L:1.0,M:48.5106,S:0.02912},37:{L:1.0,M:48.5921,S:0.02909},38:{L:1.0,M:48.6732,S:0.02906},39:{L:1.0,M:48.7487,S:0.02903},40:{L:1.0,M:48.824,S:0.029},41:{L:1.0,M:48.8942,S:0.02897},42:{L:1.0,M:48.9621,S:0.02894},43:{L:1.0,M:49.0298,S:0.02891},44:{L:1.0,M:49.0932,S:0.02888},45:{L:1.0,M:49.1566,S:0.02886},46:{L:1.0,M:49.2162,S:0.02883},47:{L:1.0,M:49.2759,S:0.0288},48:{L:1.0,M:49.3321,S:0.02878},49:{L:1.0,M:49.3869,S:0.02875},50:{L:1.0,M:49.4421,S:0.02873},51:{L:1.0,M:49.4942,S:0.0287},52:{L:1.0,M:49.5468,S:0.02868},53:{L:1.0,M:49.5966,S:0.02866},54:{L:1.0,M:49.647,S:0.02863},55:{L:1.0,M:49.6946,S:0.02861},56:{L:1.0,M:49.7413,S:0.02859},57:{L:1.0,M:49.7886,S:0.02856},58:{L:1.0,M:49.8335,S:0.02854},59:{L:1.0,M:49.8791,S:0.02852},60:{L:1.0,M:49.9225,S:0.0285}}};

    // WHO Weight-for-Length 45-110cm (every 1cm)
    var wflLMS = {male:{45:{L:-0.3521,M:2.441,S:0.09182},46:{L:-0.3521,M:2.6077,S:0.09124},47:{L:-0.3521,M:2.7755,S:0.09065},48:{L:-0.3521,M:2.948,S:0.09007},49:{L:-0.3521,M:3.1308,S:0.08948},50:{L:-0.3521,M:3.3278,S:0.0889},51:{L:-0.3521,M:3.5376,S:0.08831},52:{L:-0.3521,M:3.762,S:0.08771},53:{L:-0.3521,M:4.006,S:0.08711},54:{L:-0.3521,M:4.2693,S:0.08651},55:{L:-0.3521,M:4.5467,S:0.08592},56:{L:-0.3521,M:4.8338,S:0.08535},57:{L:-0.3521,M:5.1259,S:0.08481},58:{L:-0.3521,M:5.418,S:0.0843},59:{L:-0.3521,M:5.7074,S:0.08383},60:{L:-0.3521,M:5.9907,S:0.08342},61:{L:-0.3521,M:6.2632,S:0.08308},62:{L:-0.3521,M:6.5251,S:0.08279},63:{L:-0.3521,M:6.7786,S:0.08255},64:{L:-0.3521,M:7.0255,S:0.08236},65:{L:-0.3521,M:7.2666,S:0.08223},66:{L:-0.3521,M:7.5034,S:0.08215},67:{L:-0.3521,M:7.737,S:0.08212},68:{L:-0.3521,M:7.9674,S:0.08214},69:{L:-0.3521,M:8.1955,S:0.08219},70:{L:-0.3521,M:8.4227,S:0.08229},71:{L:-0.3521,M:8.648,S:0.08241},72:{L:-0.3521,M:8.8697,S:0.08254},73:{L:-0.3521,M:9.0865,S:0.08269},74:{L:-0.3521,M:9.2974,S:0.08283},75:{L:-0.3521,M:9.5032,S:0.08295},76:{L:-0.3521,M:9.7033,S:0.08307},77:{L:-0.3521,M:9.8963,S:0.08314},78:{L:-0.3521,M:10.0827,S:0.08318},79:{L:-0.3521,M:10.2649,S:0.08316},80:{L:-0.3521,M:10.4475,S:0.08308},81:{L:-0.3521,M:10.6352,S:0.08293},82:{L:-0.3521,M:10.8321,S:0.08273},83:{L:-0.3521,M:11.0415,S:0.08246},84:{L:-0.3521,M:11.2651,S:0.08215},85:{L:-0.3521,M:11.5007,S:0.08181},86:{L:-0.3521,M:11.7444,S:0.08145},87:{L:-0.3521,M:11.9916,S:0.08111},88:{L:-0.3521,M:12.2382,S:0.08082},89:{L:-0.3521,M:12.4815,S:0.08058},90:{L:-0.3521,M:12.7209,S:0.08041},91:{L:-0.3521,M:12.9569,S:0.0803},92:{L:-0.3521,M:13.191,S:0.08025},93:{L:-0.3521,M:13.4239,S:0.08026},94:{L:-0.3521,M:13.6572,S:0.08034},95:{L:-0.3521,M:13.8928,S:0.08047},96:{L:-0.3521,M:14.1325,S:0.08067},97:{L:-0.3521,M:14.3782,S:0.08092},98:{L:-0.3521,M:14.6316,S:0.08122},99:{L:-0.3521,M:14.8934,S:0.08157},100:{L:-0.3521,M:15.1637,S:0.08198},101:{L:-0.3521,M:15.4419,S:0.08243},102:{L:-0.3521,M:15.7276,S:0.08292},103:{L:-0.3521,M:16.0206,S:0.08343},104:{L:-0.3521,M:16.3204,S:0.08397},105:{L:-0.3521,M:16.6268,S:0.08453},106:{L:-0.3521,M:16.9401,S:0.0851},107:{L:-0.3521,M:17.2607,S:0.08568},108:{L:-0.3521,M:17.5885,S:0.08629},109:{L:-0.3521,M:17.9242,S:0.08691},110:{L:-0.3521,M:18.2689,S:0.08755}},female:{45:{L:-0.3833,M:2.4607,S:0.09029},46:{L:-0.3833,M:2.6306,S:0.09037},47:{L:-0.3833,M:2.8007,S:0.09044},48:{L:-0.3833,M:2.9741,S:0.09052},49:{L:-0.3833,M:3.156,S:0.0906},50:{L:-0.3833,M:3.3518,S:0.09068},51:{L:-0.3833,M:3.5636,S:0.09076},52:{L:-0.3833,M:3.7911,S:0.09085},53:{L:-0.3833,M:4.0332,S:0.09093},54:{L:-0.3833,M:4.2875,S:0.09102},55:{L:-0.3833,M:4.5498,S:0.0911},56:{L:-0.3833,M:4.8162,S:0.09118},57:{L:-0.3833,M:5.0837,S:0.09125},58:{L:-0.3833,M:5.3507,S:0.0913},59:{L:-0.3833,M:5.6151,S:0.09134},60:{L:-0.3833,M:5.8742,S:0.09136},61:{L:-0.3833,M:6.127,S:0.09137},62:{L:-0.3833,M:6.3738,S:0.09135},63:{L:-0.3833,M:6.6144,S:0.09131},64:{L:-0.3833,M:6.8501,S:0.09126},65:{L:-0.3833,M:7.0812,S:0.09119},66:{L:-0.3833,M:7.3076,S:0.0911},67:{L:-0.3833,M:7.5288,S:0.09101},68:{L:-0.3833,M:7.7448,S:0.0909},69:{L:-0.3833,M:7.9559,S:0.09079},70:{L:-0.3833,M:8.163,S:0.09068},71:{L:-0.3833,M:8.3666,S:0.09056},72:{L:-0.3833,M:8.5679,S:0.09043},73:{L:-0.3833,M:8.7661,S:0.09031},74:{L:-0.3833,M:8.9601,S:0.09018},75:{L:-0.3833,M:9.149,S:0.09005},76:{L:-0.3833,M:9.3337,S:0.08992},77:{L:-0.3833,M:9.5166,S:0.08979},78:{L:-0.3833,M:9.7015,S:0.08965},79:{L:-0.3833,M:9.8915,S:0.08952},80:{L:-0.3833,M:10.0891,S:0.0894},81:{L:-0.3833,M:10.2965,S:0.08928},82:{L:-0.3833,M:10.514,S:0.08918},83:{L:-0.3833,M:10.741,S:0.0891},84:{L:-0.3833,M:10.9767,S:0.08903},85:{L:-0.3833,M:11.2198,S:0.08898},86:{L:-0.3833,M:11.4684,S:0.08895},87:{L:-0.3833,M:11.7201,S:0.08895},88:{L:-0.3833,M:11.972,S:0.08896},89:{L:-0.3833,M:12.2229,S:0.089},90:{L:-0.3833,M:12.4723,S:0.08906},91:{L:-0.3833,M:12.7205,S:0.08913},92:{L:-0.3833,M:12.9681,S:0.08923},93:{L:-0.3833,M:13.2158,S:0.08934},94:{L:-0.3833,M:13.4643,S:0.08948},95:{L:-0.3833,M:13.7146,S:0.08963},96:{L:-0.3833,M:13.9676,S:0.08981},97:{L:-0.3833,M:14.2239,S:0.09},98:{L:-0.3833,M:14.4848,S:0.09021},99:{L:-0.3833,M:14.7519,S:0.09044},100:{L:-0.3833,M:15.0267,S:0.09069},101:{L:-0.3833,M:15.3108,S:0.09096},102:{L:-0.3833,M:15.6046,S:0.09125},103:{L:-0.3833,M:15.9087,S:0.09155},104:{L:-0.3833,M:16.2229,S:0.09186},105:{L:-0.3833,M:16.547,S:0.09219},106:{L:-0.3833,M:16.8814,S:0.09254},107:{L:-0.3833,M:17.2269,S:0.09289},108:{L:-0.3833,M:17.5839,S:0.09326},109:{L:-0.3833,M:17.9526,S:0.09363},110:{L:-0.3833,M:18.3324,S:0.09401}}};

    // Fenton Preterm Growth LMS (GA 22-50 weeks) — Weight in grams
    var fentonLMS = {
      male: {
        22:{L:0.21,M:496,S:0.17},24:{L:0.21,M:660,S:0.17},26:{L:0.21,M:870,S:0.16},
        28:{L:0.20,M:1124,S:0.15},30:{L:0.18,M:1430,S:0.14},32:{L:0.15,M:1795,S:0.14},
        34:{L:0.12,M:2230,S:0.13},36:{L:0.08,M:2710,S:0.13},38:{L:0.04,M:3195,S:0.12},
        40:{L:0.01,M:3530,S:0.12},42:{L:-0.02,M:3820,S:0.12},44:{L:-0.04,M:4200,S:0.12},
        46:{L:-0.06,M:4680,S:0.12},48:{L:-0.07,M:5200,S:0.12},50:{L:-0.08,M:5760,S:0.12}
      },
      female: {
        22:{L:0.23,M:474,S:0.17},24:{L:0.22,M:610,S:0.17},26:{L:0.22,M:810,S:0.16},
        28:{L:0.21,M:1040,S:0.15},30:{L:0.19,M:1330,S:0.14},32:{L:0.16,M:1680,S:0.14},
        34:{L:0.12,M:2090,S:0.13},36:{L:0.08,M:2540,S:0.13},38:{L:0.04,M:3000,S:0.12},
        40:{L:0.01,M:3340,S:0.12},42:{L:-0.02,M:3630,S:0.12},44:{L:-0.04,M:4010,S:0.12},
        46:{L:-0.06,M:4470,S:0.12},48:{L:-0.07,M:4970,S:0.12},50:{L:-0.08,M:5510,S:0.12}
      }
    };

    // Growth sub-pill navigation
    document.querySelectorAll('[data-growth]').forEach(function(pill) {
      pill.addEventListener('click', function() {
        document.querySelectorAll('[data-growth]').forEach(function(p) { p.classList.remove('active'); });
        pill.classList.add('active');
        currentGrowthType = pill.dataset.growth;
        var isFenton = currentGrowthType === 'fenton';
        var isHC = currentGrowthType === 'hcfa';
        var isWFL = currentGrowthType === 'wfl';
        document.getElementById('growth-age-field').style.display = (isFenton || isWFL) ? 'none' : '';
        document.getElementById('growth-ga-field').style.display = isFenton ? '' : 'none';
        document.getElementById('growth-hc-field').style.display = isHC ? '' : 'none';
        document.getElementById('growth-weight-field').style.display = isHC ? 'none' : '';
        document.getElementById('growth-length-field').style.display = (currentGrowthType === 'wfa') ? 'none' : (isFenton ? 'none' : '');
        var src = document.getElementById('growth-source-text');
        if (isFenton) src.textContent = 'Fenton 2013 preterm growth charts (22-50 weeks GA). Weight in grams.';
        else if (isHC) src.textContent = 'WHO head circumference-for-age (0-36 months).';
        else if (isWFL) src.textContent = 'WHO weight-for-length (45-110 cm, 0-2 years).';
        else src.textContent = 'WHO growth standards (0-2y) / CDC 2000 (2-20y).';
        document.getElementById('growth-result').classList.add('hidden');
        var chartContainer = document.getElementById('growth-chart-container');
        if (chartContainer) chartContainer.classList.add('hidden');
        if (_chartInstances['growth-chart-canvas']) { _chartInstances['growth-chart-canvas'].destroy(); _chartInstances['growth-chart-canvas'] = null; }
        // Show MPH section only for LFA
        var mphSection = document.getElementById('growth-mph-section');
        if (mphSection) mphSection.style.display = (currentGrowthType === 'lfa') ? '' : 'none';
      });
    });

    function interpolateLMS(lmsTable, val) {
      var keys = Object.keys(lmsTable).map(Number).sort(function(a,b){return a-b;});
      if (val <= keys[0]) return lmsTable[keys[0]];
      if (val >= keys[keys.length-1]) return lmsTable[keys[keys.length-1]];
      for (var i = 0; i < keys.length - 1; i++) {
        if (val >= keys[i] && val <= keys[i+1]) {
          var t = (val - keys[i]) / (keys[i+1] - keys[i]);
          var a = lmsTable[keys[i]], b = lmsTable[keys[i+1]];
          return { L: a.L + t*(b.L-a.L), M: a.M + t*(b.M-a.M), S: a.S + t*(b.S-a.S) };
        }
      }
      return lmsTable[keys[0]];
    }

    function calcZFromLMS(value, L, M, S) {
      if (Math.abs(L) < 0.001) return Math.log(value / M) / S;
      return (Math.pow(value / M, L) - 1) / (L * S);
    }

    function renderGrowthResult(label, value, unit, z, percentile) {
      var pctl = (Math.round(percentile * 100) / 100).toFixed(2);
      var cl;
      if (pctl >= 95 || pctl <= 5) cl = { color: '#f59e0b', bg: '#fef3c7', text: pctl <= 5 ? 'Below 5th percentile' : 'Above 95th percentile' };
      else if (pctl >= 85 || pctl <= 15) cl = { color: '#f97316', bg: '#ffedd5', text: pctl + 'th percentile' };
      else cl = { color: '#10b981', bg: '#d1fae5', text: pctl + 'th percentile' };

      return '<div class="calc-result-header" style="background:' + cl.bg + ';border-color:' + cl.color + ';">' +
        '<div style="font-size:18px;font-weight:700;color:' + cl.color + ';">' + cl.text + '</div>' +
        '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + label + ': ' + value + ' ' + unit + '</div>' +
      '</div>' +
      '<div class="calc-result-grid">' +
        '<div class="calc-result-item"><div class="calc-result-label">Percentile</div><div class="calc-result-value">' + pctl + '<span style="font-size:12px;">th</span></div></div>' +
        '<div class="calc-result-item"><div class="calc-result-label">Z-Score</div><div class="calc-result-value" style="font-size:16px;">' + z.toFixed(2) + '</div></div>' +
      '</div>';
    }

    document.getElementById('btn-calc-growth').addEventListener('click', function() {
      var sex = document.getElementById('growth-sex').value;
      if (!sex) { showToast('Select sex', 'error'); return; }

      var resultDiv = document.getElementById('growth-result');

      if (currentGrowthType === 'fenton') {
        var ga = parseFloat(document.getElementById('growth-ga').value);
        var wt = parseFloat(document.getElementById('growth-weight').value);
        if (!ga || !wt) { showToast('Enter gestational age and weight', 'error'); return; }
        var wtGrams = wt * 1000;
        var lms = interpolateLMS(fentonLMS[sex], ga);
        var z = calcZFromLMS(wtGrams, lms.L, lms.M, lms.S);
        var p = normalCDF(z) * 100;
        resultDiv.classList.remove('hidden');
        resultDiv.innerHTML = renderGrowthResult('Weight at ' + ga + ' weeks GA', wt + ' kg (' + Math.round(wtGrams) + 'g)', '', z, p);
        renderGrowthChart('growth-chart-canvas', 'growth-chart-container', fentonLMS[sex], ga, wtGrams, 'Gestational Age (weeks)', 'Weight (g)');
        return;
      }

      var yrEl = document.getElementById('growth-age-yr');
      var moEl = document.getElementById('growth-age-mo');
      var dyEl = document.getElementById('growth-age-d');
      var yrRaw = yrEl ? yrEl.value.trim() : '';
      var moRaw = moEl ? moEl.value.trim() : '';
      var dyRaw = dyEl ? dyEl.value.trim() : '';
      // Treat blank fields as 0, but require at least ONE field to have any value.
      // "0 days" (newborn at birth) is valid — explicit zero counts.
      if (yrRaw === '' && moRaw === '' && dyRaw === '') {
        showToast('Enter age (years, months, or days)', 'error'); return;
      }
      var yr = parseFloat(yrRaw) || 0;
      var mo = parseFloat(moRaw) || 0;
      var dy = parseFloat(dyRaw) || 0;
      var age = yr * 12 + mo + dy / 30.4375; // age in months, fractional OK
      if (age < 0) { showToast('Age cannot be negative', 'error'); return; }

      if (currentGrowthType === 'wfa') {
        var wt = parseFloat(document.getElementById('growth-weight').value);
        if (!wt) { showToast('Enter weight', 'error'); return; }
        // Use WHO for 0-60mo, CDC for >60mo
        var wfaTable = (age > 24) ? cdcWfaLMS[sex] : wfaLMS[sex];
        var wfaChartTable = (age > 24) ? cdcWfaLMS[sex] : wfaLMS[sex];
        var lms = interpolateLMS(wfaTable, age);
        var z = calcZFromLMS(wt, lms.L, lms.M, lms.S);
        var p = normalCDF(z) * 100;
        var src = (age > 24) ? 'CDC' : 'WHO';
        resultDiv.classList.remove('hidden');
        resultDiv.innerHTML = renderGrowthResult('Weight-for-Age (' + age + ' mo, ' + src + ')', wt, 'kg', z, p);
        if (age > 24) {
          var wfaYears = {}; Object.keys(wfaChartTable).forEach(function(k) { wfaYears[+(k/12).toFixed(2)] = wfaChartTable[k]; });
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', wfaYears, +(age/12).toFixed(2), wt, 'Age (years)', 'Weight (kg)');
        } else {
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', wfaChartTable, age, wt, 'Age (months)', 'Weight (kg)');
        }
      }
      else if (currentGrowthType === 'lfa') {
        var len = parseFloat(document.getElementById('growth-length').value);
        if (!len) { showToast('Enter length/height', 'error'); return; }
        // Use WHO for 0-60mo, CDC for >60mo
        var lfaTable = (age > 24) ? cdcLfaLMS[sex] : lfaLMS[sex];
        var lms = interpolateLMS(lfaTable, age);
        var z = calcZFromLMS(len, lms.L, lms.M, lms.S);
        var p = normalCDF(z) * 100;
        var src = (age > 24) ? 'CDC' : 'WHO';
        resultDiv.classList.remove('hidden');
        resultDiv.innerHTML = renderGrowthResult('Length/Height-for-Age (' + age + ' mo, ' + src + ')', len, 'cm', z, p);
        // Mid-parental height
        var mphDatasets = [];
        var motherHt = parseFloat((document.getElementById('growth-mother-ht') || {}).value);
        var fatherHt = parseFloat((document.getElementById('growth-father-ht') || {}).value);
        var mph = calcMidParentalHeight(motherHt, fatherHt, sex);
        if (mph) {
          // Calculate what percentile the MPH corresponds to using adult height LMS (~18y = 216mo)
          var adultLms = interpolateLMS(cdcLfaLMS[sex], 216);
          var mphZ = calcZFromLMS(mph.target, adultLms.L, adultLms.M, adultLms.S);
          var mphPctile = (Math.round(normalCDF(mphZ) * 10000) / 100).toFixed(2);
          resultDiv.innerHTML += '<div style="margin-top:8px;padding:8px 12px;background:#ede9fe;border-radius:6px;font-size:13px;color:#6d28d9;"><strong>Mid-Parental Height:</strong> ' + mph.target.toFixed(1) + ' cm (' + mphPctile + 'th percentile) &mdash; target range: ' + mph.low.toFixed(1) + ' - ' + mph.high.toFixed(1) + ' cm</div>';
          // MPH coordinates: use years if age > 24mo
          var mphX1 = age > 24 ? 17 : 204;
          var mphX2 = age > 24 ? 20 : 240;
          mphDatasets.push({ label: 'MPH Range', data: [{x:mphX1,y:mph.low},{x:mphX2,y:mph.low}], borderColor:'rgba(139,92,246,0.3)', backgroundColor:'rgba(139,92,246,0.1)', fill:'+1', pointRadius:0, borderWidth:1, tension:0, order:5 });
          mphDatasets.push({ label: 'MPH Upper', data: [{x:mphX1,y:mph.high},{x:mphX2,y:mph.high}], borderColor:'rgba(139,92,246,0.3)', fill:false, pointRadius:0, borderWidth:1, tension:0, order:5 });
          mphDatasets.push({ label: 'MPH ' + mph.target.toFixed(0) + 'cm (' + mphPctile + 'th %ile)', data: [{x:mphX1,y:mph.target},{x:mphX2,y:mph.target}], borderColor:'rgba(139,92,246,0.8)', borderDash:[6,3], fill:false, pointRadius:3, pointHoverRadius:6, borderWidth:2, tension:0, order:5 });
        }
        if (age > 24) {
          var lfaYears = {}; Object.keys(lfaTable).forEach(function(k) { lfaYears[+(k/12).toFixed(2)] = lfaTable[k]; });
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', lfaYears, +(age/12).toFixed(2), len, 'Age (years)', 'Length/Height (cm)', mphDatasets);
        } else {
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', lfaTable, age, len, 'Age (months)', 'Length/Height (cm)', mphDatasets);
        }
      }
      else if (currentGrowthType === 'hcfa') {
        var hc = parseFloat(document.getElementById('growth-hc').value);
        if (!hc) { showToast('Enter head circumference', 'error'); return; }
        if (age > 60) { showToast('HC charts available 0-60 months only', 'error'); return; }
        var lms = interpolateLMS(hcfaLMS[sex], age);
        var z = calcZFromLMS(hc, lms.L, lms.M, lms.S);
        var p = normalCDF(z) * 100;
        resultDiv.classList.remove('hidden');
        resultDiv.innerHTML = renderGrowthResult('Head Circumference (' + age + ' mo)', hc, 'cm', z, p);
        if (age > 24) {
          var hcYears = {}; Object.keys(hcfaLMS[sex]).forEach(function(k) { hcYears[+(k/12).toFixed(2)] = hcfaLMS[sex][k]; });
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', hcYears, +(age/12).toFixed(2), hc, 'Age (years)', 'Head Circumference (cm)');
        } else {
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', hcfaLMS[sex], age, hc, 'Age (months)', 'Head Circumference (cm)');
        }
      }
      else if (currentGrowthType === 'wfl') {
        var wt = parseFloat(document.getElementById('growth-weight').value);
        var len = parseFloat(document.getElementById('growth-length').value);
        if (!wt || !len) { showToast('Enter weight and length', 'error'); return; }
        // Use WHO Weight-for-Length if length is within 45-110cm range
        if (len >= 45 && len <= 110 && wflLMS[sex]) {
          var lms = interpolateLMS(wflLMS[sex], len);
          var z = calcZFromLMS(wt, lms.L, lms.M, lms.S);
          var p = normalCDF(z) * 100;
          resultDiv.classList.remove('hidden');
          resultDiv.innerHTML = renderGrowthResult('Weight-for-Length (' + wt + 'kg / ' + len + 'cm, WHO)', wt, 'kg', z, p);
          renderGrowthChart('growth-chart-canvas', 'growth-chart-container', wflLMS[sex], len, wt, 'Length (cm)', 'Weight (kg)');
        } else {
          // Fall back to BMI-for-Age for children outside WFL range
          var bmi = wt / Math.pow(len / 100, 2);
          var ageMonths = Math.max(24, Math.min(240, Math.round(age)));
          var lms = interpolateLMS(bmiLMS[sex], ageMonths);
          var z = calcZFromLMS(bmi, lms.L, lms.M, lms.S);
          var p = normalCDF(z) * 100;
          resultDiv.classList.remove('hidden');
          resultDiv.innerHTML = renderGrowthResult('Weight-for-Length (' + wt + 'kg / ' + len + 'cm, BMI proxy)', 'BMI ' + bmi.toFixed(1), 'kg/m2', z, p);
        }
      }
    });

    document.getElementById('btn-clear-growth').addEventListener('click', function() {
      ['growth-sex', 'growth-age-yr', 'growth-age-mo', 'growth-age-d', 'growth-ga', 'growth-weight', 'growth-length', 'growth-hc'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      var hint = document.getElementById('growth-age-parsed'); if (hint) hint.textContent = '';
      document.getElementById('growth-result').classList.add('hidden');
    });

    // Live feedback as the age fields change
    var ageHint = document.getElementById('growth-age-parsed');
    function updateAgeHint() {
      if (!ageHint) return;
      var yrRaw = ((document.getElementById('growth-age-yr') || {}).value || '').trim();
      var moRaw = ((document.getElementById('growth-age-mo') || {}).value || '').trim();
      var dyRaw = ((document.getElementById('growth-age-d') || {}).value || '').trim();
      if (yrRaw === '' && moRaw === '' && dyRaw === '') { ageHint.textContent = ''; return; }
      var total = (parseFloat(yrRaw) || 0) * 12 + (parseFloat(moRaw) || 0) + (parseFloat(dyRaw) || 0) / 30.4375;
      ageHint.style.color = 'var(--g500)';
      ageHint.textContent = formatParsedAge(total);
    }
    ['growth-age-yr', 'growth-age-mo', 'growth-age-d'].forEach(function(id) {
      var el = document.getElementById(id);
      if (el) el.addEventListener('input', updateAgeHint);
    });

    // ═══════════════════════════════════════════════════════════
    // BILIRUBIN — AAP 2022 Phototherapy + Bhutani Nomogram
    // ═══════════════════════════════════════════════════════════

    // ── Bilirubin chart helpers ──

    function generateThresholdCurve(table) {
      var keys = Object.keys(table).map(Number).sort(function(a,b){return a-b;});
      return keys.map(function(h) { return { x: h, y: table[h] }; });
    }

    function renderBiliChart(patientHours, patientTSB, curveDatasets) {
      if (typeof Chart === 'undefined') return;
      var container = document.getElementById('bili-chart-container');
      if (!container) return;
      container.classList.remove('hidden');

      if (_chartInstances['bili-chart-canvas']) { _chartInstances['bili-chart-canvas'].destroy(); _chartInstances['bili-chart-canvas'] = null; }

      var datasets = curveDatasets.map(function(ds) {
        return Object.assign({ pointRadius: 0, pointHoverRadius: 0, tension: 0.3, order: 10 }, ds);
      });

      // Patient point
      datasets.push({
        label: 'Patient',
        data: [{ x: patientHours, y: patientTSB }],
        backgroundColor: '#2563eb',
        borderColor: '#1d4ed8',
        pointRadius: 8,
        pointHoverRadius: 10,
        showLine: false,
        type: 'scatter',
        order: 0
      });

      _chartInstances['bili-chart-canvas'] = new Chart(document.getElementById('bili-chart-canvas'), {
        type: 'line',
        data: { datasets: datasets },
        options: {
          responsive: true,
          maintainAspectRatio: true,
          aspectRatio: 1.6,
          animation: { duration: 300 },
          scales: {
            x: { type: 'linear', title: { display: true, text: 'Age (hours)', font: { size: 12, weight: 'bold' } }, min: 12, max: 150, grid: { color: 'rgba(0,0,0,0.05)' } },
            y: { title: { display: true, text: 'TSB (mg/dL)', font: { size: 12, weight: 'bold' } }, min: 0, grid: { color: 'rgba(0,0,0,0.05)' } }
          },
          plugins: {
            legend: { display: true, position: 'bottom', labels: { font: { size: 11 }, usePointStyle: true, pointStyle: 'line' } },
            tooltip: {
              callbacks: {
                label: function(ctx) {
                  if (ctx.dataset.label === 'Patient') return 'Patient: ' + ctx.parsed.y.toFixed(1) + ' mg/dL at ' + ctx.parsed.x + 'h';
                  return ctx.dataset.label + ': ' + ctx.parsed.y.toFixed(1) + ' mg/dL';
                }
              }
            }
          }
        }
      });
    }

    // AAP 2022 phototherapy thresholds (TSB in mg/dL) by hour of age
    // Source: Kemper et al., Pediatrics 2022;150(3):e2022058859, Figures 2-3
    // Values read from published nomogram curves at key time points
    // NOTE: The AAP 2022 raised thresholds ~2 mg/dL above the 2004 guidelines

    // AAP 2022 EXACT hour-by-hour phototherapy thresholds (extracted from PediTools API, validated against AAP nomograms)
    // >= 38 weeks, no neurotoxicity risk factors
    var photoThresholds38 = {12:10.1,13:10.3,14:10.5,15:10.7,16:10.8,17:11,18:11.2,19:11.4,20:11.6,21:11.7,22:11.9,23:12.1,24:12.3,25:12.4,26:12.6,27:12.8,28:12.9,29:13.1,30:13.3,31:13.4,32:13.6,33:13.8,34:13.9,35:14.1,36:14.2,37:14.4,38:14.5,39:14.7,40:14.8,41:15,42:15.1,43:15.3,44:15.4,45:15.6,46:15.7,47:15.8,48:16,49:16.1,50:16.2,51:16.4,52:16.5,53:16.6,54:16.8,55:16.9,56:17,57:17.1,58:17.3,59:17.4,60:17.5,61:17.6,62:17.7,63:17.8,64:17.9,65:18.1,66:18.2,67:18.3,68:18.4,69:18.5,70:18.6,71:18.7,72:18.8,73:18.9,74:19,75:19.1,76:19.2,77:19.3,78:19.4,79:19.5,80:19.5,81:19.6,82:19.7,83:19.8,84:19.9,85:20,86:20,87:20.1,88:20.2,89:20.3,90:20.3,91:20.4,92:20.5,93:20.6,94:20.6,95:20.7,96:20.7};
    // >= 38 weeks, WITH neurotoxicity risk factors
    var photoThresholds38risk = {12:8.5,13:8.6,14:8.8,15:9,16:9.2,17:9.4,18:9.5,19:9.7,20:9.9,21:10,22:10.2,23:10.4,24:10.5,25:10.7,26:10.8,27:11,28:11.2,29:11.3,30:11.5,31:11.6,32:11.8,33:11.9,34:12.1,35:12.2,36:12.4,37:12.5,38:12.7,39:12.8,40:12.9,41:13.1,42:13.2,43:13.3,44:13.5,45:13.6,46:13.7,47:13.9,48:14,49:14.1,50:14.2,51:14.4,52:14.5,53:14.6,54:14.7,55:14.8,56:14.9,57:15.1,58:15.2,59:15.3,60:15.4,61:15.5,62:15.6,63:15.7,64:15.8,65:15.9,66:16,67:16.1,68:16.2,69:16.3,70:16.4,71:16.5,72:16.6,73:16.6,74:16.7,75:16.8,76:16.9,77:17,78:17.1,79:17.1,80:17.2,81:17.3,82:17.4,83:17.4,84:17.5,85:17.6,86:17.6,87:17.7,88:17.8,89:17.8,90:17.9,91:18,92:18,93:18.1,94:18.1,95:18.2,96:18.2};
    // 36-37 weeks, no neurotoxicity risk factors
    var photoThresholds36 = {12:9,13:9.2,14:9.4,15:9.6,16:9.8,17:9.9,18:10.1,19:10.3,20:10.5,21:10.6,22:10.8,23:11,24:11.2,25:11.3,26:11.5,27:11.7,28:11.8,29:12,30:12.1,31:12.3,32:12.5,33:12.6,34:12.8,35:12.9,36:13.1,37:13.2,38:13.4,39:13.5,40:13.7,41:13.8,42:13.9,43:14.1,44:14.2,45:14.4,46:14.5,47:14.6,48:14.8,49:14.9,50:15,51:15.1,52:15.3,53:15.4,54:15.5,55:15.6,56:15.8,57:15.9,58:16,59:16.1,60:16.2,61:16.3,62:16.5,63:16.6,64:16.7,65:16.8,66:16.9,67:17,68:17.1,69:17.2,70:17.3,71:17.4,72:17.5,73:17.6,74:17.7,75:17.8,76:17.9,77:17.9,78:18,79:18.1,80:18.2,81:18.3,82:18.4,83:18.4,84:18.5,85:18.6,86:18.7,87:18.8,88:18.8,89:18.9,90:19,91:19,92:19.1,93:19.2,94:19.2,95:19.3,96:19.3};
    // 36-37 weeks, WITH neurotoxicity risk factors
    var photoThresholds36risk = {12:7.4,13:7.6,14:7.8,15:8,16:8.1,17:8.3,18:8.5,19:8.6,20:8.8,21:9,22:9.1,23:9.3,24:9.4,25:9.6,26:9.8,27:9.9,28:10.1,29:10.2,30:10.4,31:10.5,32:10.7,33:10.8,34:11,35:11.1,36:11.2,37:11.4,38:11.5,39:11.7,40:11.8,41:11.9,42:12.1,43:12.2,44:12.3,45:12.5,46:12.6,47:12.7,48:12.8,49:13,50:13.1,51:13.2,52:13.3,53:13.4,54:13.5,55:13.7,56:13.8,57:13.9,58:14,59:14.1,60:14.2,61:14.3,62:14.4,63:14.5,64:14.6,65:14.7,66:14.8,67:14.9,68:15,69:15.1,70:15.2,71:15.3,72:15.4,73:15.4,74:15.5,75:15.6,76:15.7,77:15.8,78:15.8,79:15.9,80:16,81:16.1,82:16.1,83:16.2,84:16.3,85:16.4,86:16.4,87:16.5,88:16.6,89:16.6,90:16.7,91:16.7,92:16.8,93:16.8,94:16.9,95:17,96:17};
    // 35 weeks, no neurotoxicity risk factors
    var photoThresholds35 = {12:8.5,13:8.7,14:8.9,15:9,16:9.2,17:9.4,18:9.6,19:9.8,20:9.9,21:10.1,22:10.3,23:10.4,24:10.6,25:10.8,26:10.9,27:11.1,28:11.3,29:11.4,30:11.6,31:11.7,32:11.9,33:12,34:12.2,35:12.3,36:12.5,37:12.6,38:12.8,39:12.9,40:13.1,41:13.2,42:13.4,43:13.5,44:13.6,45:13.8,46:13.9,47:14,48:14.2,49:14.3,50:14.4,51:14.5,52:14.7,53:14.8,54:14.9,55:15,56:15.1,57:15.3,58:15.4,59:15.5,60:15.6,61:15.7,62:15.8,63:15.9,64:16,65:16.1,66:16.2,67:16.3,68:16.4,69:16.5,70:16.6,71:16.7,72:16.8,73:16.9,74:17,75:17.1,76:17.2,77:17.3,78:17.4,79:17.5,80:17.5,81:17.6,82:17.7,83:17.8,84:17.8,85:17.9,86:18,87:18.1,88:18.1,89:18.2,90:18.3,91:18.3,92:18.4,93:18.5,94:18.5,95:18.6,96:18.6};
    // 35 weeks, WITH neurotoxicity risk factors
    var photoThresholds35risk = {12:6.9,13:7.1,14:7.2,15:7.4,16:7.6,17:7.7,18:7.9,19:8.1,20:8.2,21:8.4,22:8.6,23:8.7,24:8.9,25:9,26:9.2,27:9.3,28:9.5,29:9.6,30:9.8,31:9.9,32:10.1,33:10.2,34:10.3,35:10.5,36:10.6,37:10.8,38:10.9,39:11,40:11.2,41:11.3,42:11.4,43:11.5,44:11.7,45:11.8,46:11.9,47:12,48:12.2,49:12.3,50:12.4,51:12.5,52:12.6,53:12.7,54:12.8,55:13,56:13.1,57:13.2,58:13.3,59:13.4,60:13.5,61:13.6,62:13.7,63:13.8,64:13.9,65:14,66:14.1,67:14.2,68:14.2,69:14.3,70:14.4,71:14.5,72:14.6,73:14.7,74:14.8,75:14.8,76:14.9,77:15,78:15.1,79:15.1,80:15.2,81:15.3,82:15.3,83:15.4,84:15.5,85:15.5,86:15.6,87:15.7,88:15.7,89:15.8,90:15.8,91:15.9,92:15.9,93:16,94:16.1,95:16.1,96:16.1};
    // Exchange transfusion thresholds (AAP 2022, hour-by-hour from PediTools)
    var exchangeThresholds38 = {12:19.7,13:19.9,14:20,15:20.1,16:20.3,17:20.4,18:20.6,19:20.7,20:20.8,21:21,22:21.1,23:21.2,24:21.4,25:21.5,26:21.6,27:21.7,28:21.9,29:22,30:22.1,31:22.2,32:22.3,33:22.4,34:22.6,35:22.7,36:22.8,37:22.9,38:23,39:23.1,40:23.2,41:23.3,42:23.4,43:23.5,44:23.6,45:23.7,46:23.8,47:23.9,48:24,49:24.1,50:24.2,51:24.3,52:24.4,53:24.5,54:24.6,55:24.7,56:24.7,57:24.8,58:24.9,59:25,60:25.1,61:25.2,62:25.2,63:25.3,64:25.4,65:25.5,66:25.5,67:25.6,68:25.7,69:25.7,70:25.8,71:25.9,72:25.9,73:26,74:26,75:26.1,76:26.2,77:26.2,78:26.3,79:26.3,80:26.4,81:26.4,82:26.5,83:26.5,84:26.6,85:26.6,86:26.7,87:26.7,88:26.7,89:26.8,90:26.8,91:26.9,92:26.9,93:26.9,94:27,95:27,96:27};
    var exchangeThresholds38risk = {12:16.3,13:16.4,14:16.5,15:16.6,16:16.7,17:16.9,18:17,19:17.1,20:17.2,21:17.3,22:17.4,23:17.6,24:17.7,25:17.8,26:17.9,27:18,28:18.1,29:18.2,30:18.3,31:18.4,32:18.5,33:18.7,34:18.8,35:18.9,36:19,37:19.1,38:19.2,39:19.3,40:19.4,41:19.5,42:19.6,43:19.7,44:19.8,45:19.9,46:19.9,47:20,48:20.1,49:20.2,50:20.3,51:20.4,52:20.5,53:20.6,54:20.7,55:20.8,56:20.8,57:20.9,58:21,59:21.1,60:21.2,61:21.3,62:21.3,63:21.4,64:21.5,65:21.6,66:21.7,67:21.7,68:21.8,69:21.9,70:22,71:22,72:22.1,73:22.2,74:22.2,75:22.3,76:22.4,77:22.5,78:22.5,79:22.6,80:22.7,81:22.7,82:22.8,83:22.8,84:22.9,85:23,86:23,87:23.1,88:23.1,89:23.2,90:23.3,91:23.3,92:23.4,93:23.4,94:23.5,95:23.5,96:23.5};
    var exchangeThresholds36 = {12:17.5,13:17.7,14:17.8,15:17.9,16:18.1,17:18.2,18:18.3,19:18.5,20:18.6,21:18.7,22:18.9,23:19,24:19.1,25:19.2,26:19.4,27:19.5,28:19.6,29:19.7,30:19.9,31:20,32:20.1,33:20.2,34:20.4,35:20.5,36:20.6,37:20.7,38:20.8,39:20.9,40:21,41:21.2,42:21.3,43:21.4,44:21.5,45:21.6,46:21.7,47:21.8,48:21.9,49:22,50:22.1,51:22.2,52:22.3,53:22.4,54:22.5,55:22.6,56:22.7,57:22.8,58:22.9,59:23,60:23.1,61:23.2,62:23.2,63:23.3,64:23.4,65:23.5,66:23.6,67:23.7,68:23.8,69:23.8,70:23.9,71:24,72:24.1,73:24.1,74:24.2,75:24.3,76:24.4,77:24.4,78:24.5,79:24.6,80:24.6,81:24.7,82:24.8,83:24.8,84:24.9,85:25,86:25,87:25.1,88:25.2,89:25.2,90:25.3,91:25.3,92:25.4,93:25.4,94:25.5,95:25.5,96:25.5};
    var exchangeThresholds36risk = {12:15.2,13:15.3,14:15.4,15:15.6,16:15.7,17:15.8,18:15.9,19:16.1,20:16.2,21:16.3,22:16.4,23:16.5,24:16.6,25:16.8,26:16.9,27:17,28:17.1,29:17.2,30:17.3,31:17.4,32:17.5,33:17.6,34:17.7,35:17.8,36:17.9,37:18,38:18.1,39:18.2,40:18.3,41:18.4,42:18.5,43:18.6,44:18.7,45:18.8,46:18.9,47:19,48:19.1,49:19.2,50:19.2,51:19.3,52:19.4,53:19.5,54:19.6,55:19.7,56:19.7,57:19.8,58:19.9,59:20,60:20.1,61:20.1,62:20.2,63:20.3,64:20.3,65:20.4,66:20.5,67:20.6,68:20.6,69:20.7,70:20.8,71:20.8,72:20.9,73:20.9,74:21,75:21.1,76:21.1,77:21.2,78:21.2,79:21.3,80:21.4,81:21.4,82:21.5,83:21.5,84:21.6,85:21.6,86:21.7,87:21.7,88:21.8,89:21.8,90:21.9,91:21.9,92:22,93:22,94:22,95:22.1,96:22.1};
    var exchangeThresholds35 = {12:16.4,13:16.5,14:16.6,15:16.8,16:16.9,17:17,18:17.2,19:17.3,20:17.4,21:17.5,22:17.7,23:17.8,24:17.9,25:18,26:18.2,27:18.3,28:18.4,29:18.5,30:18.7,31:18.8,32:18.9,33:19,34:19.1,35:19.2,36:19.4,37:19.5,38:19.6,39:19.7,40:19.8,41:19.9,42:20,43:20.1,44:20.2,45:20.3,46:20.5,47:20.6,48:20.7,49:20.8,50:20.9,51:21,52:21.1,53:21.2,54:21.3,55:21.4,56:21.5,57:21.6,58:21.7,59:21.7,60:21.8,61:21.9,62:22,63:22.1,64:22.2,65:22.3,66:22.4,67:22.5,68:22.6,69:22.6,70:22.7,71:22.8,72:22.9,73:23,74:23.1,75:23.1,76:23.2,77:23.3,78:23.4,79:23.4,80:23.5,81:23.6,82:23.7,83:23.7,84:23.8,85:23.9,86:23.9,87:24,88:24.1,89:24.1,90:24.2,91:24.3,92:24.3,93:24.4,94:24.4,95:24.5,96:24.5};
    var exchangeThresholds35risk = {12:14.6,13:14.8,14:14.9,15:15,16:15.1,17:15.3,18:15.4,19:15.5,20:15.6,21:15.8,22:15.9,23:16,24:16.1,25:16.2,26:16.3,27:16.4,28:16.5,29:16.6,30:16.8,31:16.9,32:17,33:17.1,34:17.2,35:17.3,36:17.4,37:17.5,38:17.6,39:17.7,40:17.7,41:17.8,42:17.9,43:18,44:18.1,45:18.2,46:18.3,47:18.4,48:18.5,49:18.5,50:18.6,51:18.7,52:18.8,53:18.9,54:18.9,55:19,56:19.1,57:19.2,58:19.2,59:19.3,60:19.4,61:19.4,62:19.5,63:19.6,64:19.6,65:19.7,66:19.8,67:19.8,68:19.9,69:19.9,70:20,71:20.1,72:20.1,73:20.2,74:20.2,75:20.3,76:20.3,77:20.4,78:20.4,79:20.5,80:20.5,81:20.6,82:20.6,83:20.6,84:20.7,85:20.7,86:20.8,87:20.8,88:20.8,89:20.9,90:20.9,91:20.9,92:21,93:21,94:21,95:21.1,96:21.1};

    function interpolateThreshold(table, hours) {
      var keys = Object.keys(table).map(Number).sort(function(a,b){return a-b;});
      if (hours <= keys[0]) return table[keys[0]];
      if (hours >= keys[keys.length-1]) return table[keys[keys.length-1]];
      for (var i = 0; i < keys.length-1; i++) {
        if (hours >= keys[i] && hours <= keys[i+1]) {
          var t = (hours - keys[i]) / (keys[i+1] - keys[i]);
          return table[keys[i]] + t * (table[keys[i+1]] - table[keys[i]]);
        }
      }
      return table[keys[0]];
    }

    // Bili sub-pill nav
    document.querySelectorAll('[data-bili]').forEach(function(pill) {
      pill.addEventListener('click', function() {
        document.querySelectorAll('[data-bili]').forEach(function(p) { p.classList.remove('active'); });
        pill.classList.add('active');
        document.getElementById('bili-aap-panel').style.display = pill.dataset.bili === 'aap' ? '' : 'none';
        document.getElementById('bili-bhutani-panel').style.display = pill.dataset.bili === 'bhutani' ? '' : 'none';
        document.getElementById('bili-result').classList.add('hidden');
        var biliChartC = document.getElementById('bili-chart-container');
        if (biliChartC) biliChartC.classList.add('hidden');
        if (_chartInstances['bili-chart-canvas']) { _chartInstances['bili-chart-canvas'].destroy(); _chartInstances['bili-chart-canvas'] = null; }
      });
    });

    document.getElementById('btn-calc-bili-aap').addEventListener('click', function() {
      var ga = document.getElementById('bili-ga').value;
      var hours = parseFloat(document.getElementById('bili-age-hours').value);
      var tsb = parseFloat(document.getElementById('bili-tsb').value);
      var risk = document.getElementById('bili-risk').value;
      if (!ga || isNaN(hours) || isNaN(tsb)) { showToast('Fill in all fields', 'error'); return; }

      var gaNum = parseInt(ga);
      var table;
      if (gaNum >= 38) table = risk === 'medium' ? photoThresholds38risk : photoThresholds38;
      else if (gaNum === 36 || gaNum === 37) table = risk === 'medium' ? photoThresholds36risk : photoThresholds36;
      else table = risk === 'medium' ? photoThresholds35risk : photoThresholds35;

      var threshold = interpolateThreshold(table, hours);
      var aboveThreshold = tsb >= threshold;

      // Check exchange transfusion threshold too
      var exchangeTable;
      if (gaNum >= 38) exchangeTable = risk === 'medium' ? exchangeThresholds38risk : exchangeThresholds38;
      else if (gaNum >= 36) exchangeTable = risk === 'medium' ? exchangeThresholds36risk : exchangeThresholds36;
      else exchangeTable = risk === 'medium' ? exchangeThresholds35risk : exchangeThresholds35;
      var exchangeThreshold = exchangeTable ? interpolateThreshold(exchangeTable, hours) : null;
      var aboveExchange = exchangeThreshold && tsb >= exchangeThreshold;

      var cl;
      if (aboveExchange) cl = { text: 'ABOVE EXCHANGE TRANSFUSION THRESHOLD', color: '#7f1d1d', bg: '#fecaca' };
      else if (aboveThreshold) cl = { text: 'Above Phototherapy Threshold', color: '#ef4444', bg: '#fee2e2' };
      else cl = { text: 'Below Phototherapy Threshold', color: '#10b981', bg: '#d1fae5' };

      var resultDiv = document.getElementById('bili-result');
      resultDiv.classList.remove('hidden');
      resultDiv.innerHTML =
        '<div class="calc-result-header" style="background:' + cl.bg + ';border-color:' + cl.color + ';">' +
          '<div style="font-size:18px;font-weight:700;color:' + cl.color + ';">' + cl.text + '</div>' +
          '<div style="font-size:13px;color:var(--g600);margin-top:4px;">TSB ' + tsb + ' mg/dL at ' + hours + ' hours of life</div>' +
        '</div>' +
        '<div class="calc-result-grid">' +
          '<div class="calc-result-item"><div class="calc-result-label">Patient TSB</div><div class="calc-result-value">' + tsb + '</div><div class="calc-result-sub">mg/dL</div></div>' +
          '<div class="calc-result-item"><div class="calc-result-label">Photo Threshold</div><div class="calc-result-value">' + threshold.toFixed(1) + '</div><div class="calc-result-sub">mg/dL at ' + hours + 'h</div></div>' +
          '<div class="calc-result-item"><div class="calc-result-label">Margin</div><div class="calc-result-value" style="color:' + cl.color + ';">' + (tsb >= threshold ? '+' : '') + (tsb - threshold).toFixed(1) + '</div><div class="calc-result-sub">mg/dL ' + (aboveThreshold ? 'above' : 'below') + ' photo</div></div>' +
          (exchangeThreshold ? '<div class="calc-result-item"><div class="calc-result-label">Exchange Threshold</div><div class="calc-result-value" style="color:#7f1d1d;">' + exchangeThreshold.toFixed(1) + '</div><div class="calc-result-sub">mg/dL' + (aboveExchange ? ' — EXCEEDED' : '') + '</div></div>' : '') +
        '</div>' +
        '<p style="font-size:11px;color:var(--g400);margin:12px 0 0;">GA ' + ga + ' weeks, ' + (risk === 'medium' ? 'with' : 'without') + ' neurotoxicity risk factors. AAP 2022 CPG (exact values from published nomograms). Always use clinical judgment.</p>';

      // Chart: phototherapy + exchange threshold lines vs patient
      var chartDatasets = [
        { label: 'Phototherapy Threshold', data: generateThresholdCurve(table), borderColor: '#ef4444', borderWidth: 2, borderDash: [], fill: { target: 'origin', above: 'rgba(239,68,68,0.08)' } }
      ];
      if (exchangeTable) {
        chartDatasets.push({ label: 'Exchange Transfusion', data: generateThresholdCurve(exchangeTable), borderColor: '#7f1d1d', borderWidth: 2, borderDash: [6,3], fill: false });
      }
      renderBiliChart(hours, tsb, chartDatasets);
    });

    document.getElementById('btn-clear-bili-aap').addEventListener('click', function() {
      ['bili-ga', 'bili-age-hours', 'bili-tsb', 'bili-risk'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      document.getElementById('bili-result').classList.add('hidden');
      var bc = document.getElementById('bili-chart-container'); if (bc) bc.classList.add('hidden');
    });

    // Bhutani 1999 hour-specific risk nomogram — 40th / 75th / 95th
    // percentile TSB boundaries. Values are a pre-digitized transcription
    // of the original Figure 2 (Bhutani VK et al., Pediatrics 1999;103(1):6-14),
    // lifted verbatim from the JS data arrays used by the codingace.net
    // Bhutani calculator:
    //   https://codingace.net/health/neonate_bilirubin_bhutani.html
    // Cross-checked against the AAP 2004 CPG reproduction of the same chart:
    //   https://staffnet.southernhealth.ca/wp-content/uploads/Bhutani-Nomogram.pdf
    //   (Reproduced with AAP permission from Pediatrics 2004;114:297-316)
    // 6-hour granularity through the first 72 h, 12-hour after.
    //
    // Zone semantics (per AAP 2004 reproduction legend):
    //   High-risk:         TSB >= 95th percentile
    //   High-intermediate: 75th <= TSB < 95th
    //   Low-intermediate:  40th <= TSB < 75th
    //   Low-risk:          TSB < 40th
    //
    // Clinical note: this nomogram is for RISK STRATIFICATION only.
    // For phototherapy/exchange decisions use the AAP 2022 tab
    // (which supersedes the 2004 treatment thresholds).
    var bhutaniZones = {
      p95: { 6:6.0,  12:7.2,  18:8.5,  24:9.6,  30:11.2, 36:12.8, 42:13.8, 48:14.8,
             54:15.6, 60:16.2, 66:16.8, 72:17.4, 84:18.0, 96:18.4, 108:18.8, 120:19.0 },
      p75: { 6:4.5,  12:5.5,  18:6.6,  24:7.8,  30:9.2,  36:10.6, 42:11.6, 48:12.6,
             54:13.4, 60:14.0, 66:14.6, 72:15.0, 84:15.4, 96:15.6, 108:15.8, 120:16.0 },
      p40: { 6:3.0,  12:4.0,  18:5.0,  24:6.2,  30:7.2,  36:8.4,  42:9.2,  48:10.0,
             54:10.6, 60:11.2, 66:11.8, 72:12.2, 84:12.6, 96:12.8, 108:13.0, 120:13.2 }
    };

    document.getElementById('btn-calc-bhutani').addEventListener('click', function() {
      var hours = parseFloat(document.getElementById('bhutani-age').value);
      var tsb = parseFloat(document.getElementById('bhutani-tsb').value);
      if (isNaN(hours) || isNaN(tsb)) { showToast('Fill in all fields', 'error'); return; }

      var p95 = interpolateThreshold(bhutaniZones.p95, hours);
      var p75 = interpolateThreshold(bhutaniZones.p75, hours);
      var p40 = interpolateThreshold(bhutaniZones.p40, hours);

      var zone, cl;
      if (tsb >= p95)      { zone = 'High-Risk Zone'; cl = { color: '#ef4444', bg: '#fee2e2' }; }
      else if (tsb >= p75) { zone = 'High-Intermediate Zone'; cl = { color: '#f97316', bg: '#ffedd5' }; }
      else if (tsb >= p40) { zone = 'Low-Intermediate Zone'; cl = { color: '#f59e0b', bg: '#fef3c7' }; }
      else                 { zone = 'Low-Risk Zone'; cl = { color: '#10b981', bg: '#d1fae5' }; }

      var resultDiv = document.getElementById('bili-result');
      resultDiv.classList.remove('hidden');
      resultDiv.innerHTML =
        '<div class="calc-result-header" style="background:' + cl.bg + ';border-color:' + cl.color + ';">' +
          '<div style="font-size:18px;font-weight:700;color:' + cl.color + ';">' + zone + '</div>' +
          '<div style="font-size:13px;color:var(--g600);margin-top:4px;">TSB ' + tsb + ' mg/dL at ' + hours + ' hours of life</div>' +
        '</div>' +
        '<div class="calc-result-grid">' +
          '<div class="calc-result-item"><div class="calc-result-label">95th %ile</div><div class="calc-result-value" style="font-size:16px;color:#ef4444;">' + p95.toFixed(1) + '</div><div class="calc-result-sub">High-risk</div></div>' +
          '<div class="calc-result-item"><div class="calc-result-label">75th %ile</div><div class="calc-result-value" style="font-size:16px;color:#f97316;">' + p75.toFixed(1) + '</div><div class="calc-result-sub">High-intermediate</div></div>' +
          '<div class="calc-result-item"><div class="calc-result-label">40th %ile</div><div class="calc-result-value" style="font-size:16px;color:#f59e0b;">' + p40.toFixed(1) + '</div><div class="calc-result-sub">Low-intermediate</div></div>' +
        '</div>' +
        '<p style="font-size:11px;color:var(--g400);margin:12px 0 0;">Bhutani hour-specific risk nomogram for infants &ge; 35 weeks GA. Digitized values from Bhutani et al., Pediatrics 1999 (cross-checked against the AAP 2004 CPG reproduction). For phototherapy decisions use the AAP 2022 tab.</p>';

      // Chart: Bhutani zone curves with patient
      renderBiliChart(hours, tsb, [
        { label: '95th (High-Risk)', data: generateThresholdCurve(bhutaniZones.p95), borderColor: '#ef4444', borderWidth: 2, fill: false, borderDash: [] },
        { label: '75th (High-Intermed)', data: generateThresholdCurve(bhutaniZones.p75), borderColor: '#f97316', borderWidth: 1.5, fill: { target: '-1', above: 'rgba(239,68,68,0.08)' }, borderDash: [3,3] },
        { label: '40th (Low-Intermed)', data: generateThresholdCurve(bhutaniZones.p40), borderColor: '#f59e0b', borderWidth: 1.5, fill: { target: '-1', above: 'rgba(249,115,22,0.08)' }, borderDash: [3,3] }
      ]);
    });

    document.getElementById('btn-clear-bhutani').addEventListener('click', function() {
      ['bhutani-age', 'bhutani-tsb'].forEach(function(id) {
        var el = document.getElementById(id); if (el) el.value = '';
      });
      document.getElementById('bili-result').classList.add('hidden');
      var bc = document.getElementById('bili-chart-container'); if (bc) bc.classList.add('hidden');
    });

    // ═══════════════════════════════════════════════════════════
    // VITAL SIGNS — Interactive age selector
    // Harriet Lane Handbook 23rd Edition reference values
    // ═══════════════════════════════════════════════════════════

    var VITALS_DATA = {
      premie: {
        label: 'Premie',
        hr: { awake: '120-170', sleeping: '100-150' },
        rr: '40-70',
        sbp: '55-75', dbp: '35-45',
        temp: '36.5-37.5',
        weight: '0.5-2.5 kg',
        spo2: '88-95% (target)',
        notes: [
          'HR and RR are highly variable and depend on gestational age',
          'BP increases with gestational age and postnatal age',
          'Target SpO2 88-95% to reduce retinopathy of prematurity risk',
          'Temperature instability is common — use servo-controlled warmers',
          'Bradycardia (<100 bpm) and apnea are common in premature infants'
        ]
      },
      '0-3mo': {
        label: '0-3 Months',
        hr: { awake: '100-150', sleeping: '85-135' },
        rr: '35-55',
        sbp: '65-85', dbp: '45-55',
        temp: '36.5-37.5',
        weight: '2.5-6 kg',
        spo2: '>95%',
        notes: [
          'HR normally increases with crying (up to 180-190 bpm) — this is physiologic',
          'Periodic breathing (pauses <10 sec) is normal in neonates',
          'Acrocyanosis (blue hands/feet) is normal; central cyanosis is not',
          'BP is best measured in the right arm (pre-ductal) in neonates',
          'Normal weight loss of 5-7% in first 3-5 days; regain by 10-14 days'
        ]
      },
      '3-6mo': {
        label: '3-6 Months',
        hr: { awake: '90-120', sleeping: '75-110' },
        rr: '30-45',
        sbp: '70-90', dbp: '50-65',
        temp: '36.5-37.5',
        weight: '5-8 kg',
        spo2: '>95%',
        notes: [
          'Expected weight gain: 20-30 g/day (150-200 g/week)',
          'HR gradually decreases as vagal tone matures',
          'RR >60 at rest may indicate lower respiratory tract disease',
          'BP should be measured with appropriate cuff size (width 40% of arm circumference)'
        ]
      },
      '6-12mo': {
        label: '6-12 Months',
        hr: { awake: '80-120', sleeping: '70-110' },
        rr: '25-40',
        sbp: '80-100', dbp: '55-65',
        temp: '36.0-37.5',
        weight: '8-10 kg',
        spo2: '>95%',
        notes: [
          'Expected weight: triple birth weight by 12 months (~10 kg average)',
          'Weight gain slows to ~10-15 g/day',
          'Sinus arrhythmia (HR varies with breathing) is normal',
          'Febrile tachycardia: HR increases ~10 bpm per 1 degree C above 37'
        ]
      },
      '1-3yr': {
        label: '1-3 Years',
        hr: { awake: '70-110', sleeping: '60-100' },
        rr: '20-30',
        sbp: '90-105', dbp: '55-70',
        temp: '36.0-37.5',
        weight: '10-15 kg',
        spo2: '>95%',
        notes: [
          'Expected weight gain: ~200-250 g/month (2-2.5 kg/year)',
          'Tachycardia: HR >110 at rest warrants evaluation',
          'Tachypnea: RR >30 at rest may indicate respiratory distress',
          'BP screening begins at age 3 per AAP 2017 guidelines',
          'Estimated weight: 2 x (age in years) + 8'
        ]
      },
      '3-6yr': {
        label: '3-6 Years',
        hr: { awake: '65-110', sleeping: '55-100' },
        rr: '20-25',
        sbp: '95-110', dbp: '60-75',
        temp: '36.0-37.5',
        weight: '14-20 kg',
        spo2: '>95%',
        notes: [
          'Annual BP screening recommended from age 3',
          'Normal BP <90th percentile for age, sex, and height',
          'Elevated BP: 90th to <95th percentile (or 120/80 if lower)',
          'Estimated weight: 2 x (age in years) + 8',
          'ETT size (uncuffed): (age/4) + 4'
        ]
      },
      '6-12yr': {
        label: '6-12 Years',
        hr: { awake: '60-95', sleeping: '50-85' },
        rr: '14-22',
        sbp: '100-120', dbp: '60-75',
        temp: '36.0-37.5',
        weight: '20-40 kg',
        spo2: '>95%',
        notes: [
          'Resting HR >95 or <60 warrants evaluation',
          'BP should be measured at every clinical encounter',
          'Stage 1 HTN: >=95th percentile on 3 separate occasions',
          'Estimated weight: 3 x (age in years) + 7',
          'ETT size (cuffed): (age/4) + 3.5'
        ]
      },
      '>12yr': {
        label: '>12 Years',
        hr: { awake: '55-85', sleeping: '45-75' },
        rr: '12-18',
        sbp: '110-135', dbp: '65-85',
        temp: '36.0-37.5',
        weight: '40-80 kg',
        spo2: '>95%',
        notes: [
          'Vital signs approach adult values',
          'From age 13: use adult BP thresholds (AAP 2017)',
          'Normal: <120/<80 mmHg; Elevated: 120-129/<80 mmHg',
          'Stage 1 HTN: 130-139/80-89 mmHg; Stage 2 HTN: >=140/>=90 mmHg',
          'Orthostatic vitals: measure lying, sitting, standing if dizzy',
          'Athletic bradycardia (HR 45-60) may be normal in trained adolescents'
        ]
      }
    };

    // Use event delegation on the vitals panel so the listener works even
    // when the panel is hidden at init time (hidden elements are still in the DOM,
    // but a setTimeout-based approach can race with dynamic content loading).
    var vitalsPanel = document.getElementById('calc-vitals');
    if (vitalsPanel) {
      vitalsPanel.addEventListener('change', function(e) {
        if (e.target.id !== 'vitals-age-select') return;
        var key = e.target.value;
        var resultDiv = document.getElementById('vitals-result');
        if (!key || !VITALS_DATA[key]) { resultDiv.classList.add('hidden'); return; }

        var v = VITALS_DATA[key];
        resultDiv.classList.remove('hidden');
        resultDiv.innerHTML =
          '<div class="calc-result-header" style="background:#eff6ff;border-color:#2563eb;">' +
            '<div style="font-size:18px;font-weight:700;color:#1d4ed8;">' + v.label + '</div>' +
          '</div>' +
          '<div class="calc-result-grid" style="margin-top:12px;">' +
            '<div class="calc-result-item"><div class="calc-result-label">Heart Rate (awake)</div><div class="calc-result-value" style="font-size:18px;color:#ef4444;">' + v.hr.awake + '</div><div class="calc-result-sub">bpm</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Heart Rate (sleep)</div><div class="calc-result-value" style="font-size:18px;color:#8b5cf6;">' + v.hr.sleeping + '</div><div class="calc-result-sub">bpm</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Respiratory Rate</div><div class="calc-result-value" style="font-size:18px;color:#0ea5e9;">' + v.rr + '</div><div class="calc-result-sub">breaths/min</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Systolic BP</div><div class="calc-result-value" style="font-size:18px;color:#f97316;">' + v.sbp + '</div><div class="calc-result-sub">mmHg</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Diastolic BP</div><div class="calc-result-value" style="font-size:18px;color:#f59e0b;">' + v.dbp + '</div><div class="calc-result-sub">mmHg</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Temperature</div><div class="calc-result-value" style="font-size:18px;color:#10b981;">' + v.temp + '</div><div class="calc-result-sub">&deg;C</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">SpO2</div><div class="calc-result-value" style="font-size:18px;color:#06b6d4;">' + v.spo2 + '</div><div class="calc-result-sub"></div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Weight Range</div><div class="calc-result-value" style="font-size:18px;color:#6366f1;">' + v.weight + '</div><div class="calc-result-sub"></div></div>' +
          '</div>' +
          '<div style="margin-top:14px;padding:12px;background:var(--g50);border-radius:8px;">' +
            '<div style="font-size:12px;font-weight:600;color:var(--g600);margin-bottom:6px;">Clinical Notes</div>' +
            '<ul style="margin:0;padding-left:16px;font-size:12px;color:var(--g700);line-height:1.7;">' +
              v.notes.map(function(n) { return '<li>' + n + '</li>'; }).join('') +
            '</ul>' +
          '</div>';
      });
    }

    // ═══════════════════════════════════════════════════════════
    // RESUSCITATION MEDICATIONS — Harriet Lane Handbook / AHA PALS 2020
    // ═══════════════════════════════════════════════════════════

    var RESUS_MEDS = [
      {
        name: 'Adenosine', indication: 'SVT', category: 'cardiac',
        route: 'IV/IO rapid bolus',
        calc: function(w) {
          var d1 = +(w * 0.1).toFixed(2);
          var d2 = +(w * 0.2).toFixed(2);
          var d3 = +(w * 0.3).toFixed(2);
          return {
            dose: d1 + ' mg (0.1 mg/kg)',
            extra: 'May repeat: ' + Math.min(d2, 12) + ' mg (0.2 mg/kg), then ' + Math.min(d3, 12) + ' mg (0.3 mg/kg)',
            max: 'Max first dose 6 mg, max subsequent 12 mg'
          };
        }
      },
      {
        name: 'Amiodarone', indication: 'VT / VF', category: 'cardiac',
        route: 'IV/IO',
        calc: function(w) {
          var d = +(w * 5).toFixed(1);
          return {
            dose: Math.min(d, 300) + ' mg (5 mg/kg)',
            extra: 'No pulse: push undiluted. Pulse: over 20-60 min. Subsequent max 150 mg.',
            max: 'Max first 300 mg, max total 15 mg/kg/24hr or 2200 mg'
          };
        }
      },
      {
        name: 'Atropine', indication: 'Bradycardia', category: 'cardiac',
        route: 'IV/IO/IM',
        calc: function(w) {
          var d = +(w * 0.02).toFixed(3);
          var ett = (w * 0.04).toFixed(3) + '-' + (w * 0.06).toFixed(3);
          return {
            dose: Math.min(d, 0.5) + ' mg (0.02 mg/kg)',
            extra: 'ETT dose: ' + ett + ' mg (0.04-0.06 mg/kg)',
            max: 'Max single 0.5 mg, max total 1 mg'
          };
        }
      },
      {
        name: 'Calcium Chloride 10%', indication: 'Hypocalcemia / Hyperkalemia', category: 'metabolic',
        route: 'IV/IO',
        calc: function(w) {
          var d = +(w * 20).toFixed(0);
          return {
            dose: Math.min(d, 1000) + ' mg (20 mg/kg)',
            extra: 'Give slowly. Central line preferred.',
            max: 'Max 1 g (1000 mg)'
          };
        }
      },
      {
        name: 'Calcium Gluconate 10%', indication: 'Hypocalcemia / Hyperkalemia', category: 'metabolic',
        route: 'IV/IO',
        calc: function(w) {
          var d = +(w * 60).toFixed(0);
          return {
            dose: Math.min(d, 3000) + ' mg (60 mg/kg)',
            extra: 'Give slowly over 10-20 min with cardiac monitoring.',
            max: 'Max 3 g (3000 mg)'
          };
        }
      },
      {
        name: 'Dextrose', indication: 'Hypoglycemia', category: 'metabolic',
        route: 'IV',
        calc: function(w) {
          var grams = +(w * 0.5).toFixed(1) + '-' + +(w * 1).toFixed(1);
          var detail = '';
          if (w < 5) {
            var ml = (w * 5).toFixed(1) + '-' + (w * 10).toFixed(1);
            detail = 'D10W: ' + ml + ' mL (5-10 mL/kg)';
          } else if (w < 45) {
            var ml = (w * 2).toFixed(1) + '-' + (w * 4).toFixed(1);
            detail = 'D25W: ' + ml + ' mL (2-4 mL/kg)';
          } else {
            var ml = (w * 1).toFixed(1) + '-' + (w * 2).toFixed(1);
            detail = 'D50W: ' + ml + ' mL (1-2 mL/kg)';
          }
          return {
            dose: grams + ' g (0.5-1 g/kg)',
            extra: detail,
            max: 'Max 25 g'
          };
        }
      },
      {
        name: 'Epinephrine', indication: 'Pulseless arrest / Anaphylaxis', category: 'cardiac',
        route: 'IV/IO/IM/ETT',
        calc: function(w) {
          var iv = +(w * 0.01).toFixed(3);
          var ivVol = +(w * 0.1).toFixed(2);
          var ett = +(w * 0.1).toFixed(2);
          var im = +(w * 0.01).toFixed(3);
          return {
            dose: Math.min(iv, 1) + ' mg IV/IO (0.01 mg/kg of 0.1 mg/mL = ' + Math.min(ivVol, 10) + ' mL) q3-5 min',
            extra: 'ETT: ' + Math.min(ett, 2.5) + ' mg (0.1 mg/kg of 1 mg/mL). Anaphylaxis IM: ' + Math.min(im, 0.5) + ' mg (0.01 mg/kg)',
            max: 'Max IV 1 mg, max ETT 2.5 mg, max IM 0.5 mg'
          };
        }
      },
      {
        name: 'Hydrocortisone', indication: 'Adrenal crisis', category: 'metabolic',
        route: 'IV/IM/IO',
        calc: function(w) {
          var d = +(w * 2).toFixed(1);
          return {
            dose: Math.min(d, 100) + ' mg (2 mg/kg)',
            extra: 'Stress dosing for adrenal insufficiency.',
            max: 'Max 100 mg'
          };
        }
      },
      {
        name: 'Insulin (Regular)', indication: 'Hyperkalemia', category: 'metabolic',
        route: 'IV',
        calc: function(w) {
          var d = +(w * 0.1).toFixed(2);
          var dex = +(w * 0.5).toFixed(1);
          return {
            dose: Math.min(d, 5) + ' units (0.1 units/kg)',
            extra: 'Give with ' + dex + ' g/kg dextrose (0.5 g/kg). Monitor glucose closely.',
            max: 'Max 5 units'
          };
        }
      },
      {
        name: 'Lidocaine', indication: 'Antiarrhythmic', category: 'cardiac',
        route: 'IV/IO',
        calc: function(w) {
          var d = +(w * 1).toFixed(1);
          var ett = (w * 2).toFixed(1) + '-' + (w * 3).toFixed(1);
          return {
            dose: Math.min(d, 100) + ' mg (1 mg/kg)',
            extra: 'ETT: ' + ett + ' mg (2-3 mg/kg). May repeat q5 min.',
            max: 'Max 100 mg/dose, max total 3 mg/kg'
          };
        }
      },
      {
        name: 'Magnesium Sulfate', indication: 'Torsades de Pointes', category: 'cardiac',
        route: 'IV/IO',
        calc: function(w) {
          var d = +(w * 50).toFixed(0);
          return {
            dose: Math.min(d, 2000) + ' mg (50 mg/kg)',
            extra: 'Give over 10-20 min (faster if pulseless).',
            max: 'Max 2 g (2000 mg)'
          };
        }
      },
      {
        name: 'Naloxone', indication: 'Opioid overdose', category: 'reversal',
        route: 'IV/IO/IM/IN/ETT',
        calc: function(w) {
          var partial = +(w * 0.001).toFixed(4) + '-' + +(w * 0.005).toFixed(4);
          var full = +(w * 0.1).toFixed(3);
          return {
            dose: 'Partial: ' + partial + ' mg (0.001-0.005 mg/kg)',
            extra: 'Full reversal: ' + Math.min(full, 2) + ' mg (0.1 mg/kg)',
            max: 'Max partial first dose 0.1 mg, max full 2 mg'
          };
        }
      },
      {
        name: 'Sodium Bicarbonate', indication: 'Metabolic acidosis', category: 'metabolic',
        route: 'IV/IO',
        calc: function(w) {
          var d = +(w * 1).toFixed(1);
          return {
            dose: Math.min(d, 50) + ' mEq (1 mEq/kg)',
            extra: w < 10 ? 'Dilute to 0.5 mEq/mL (use 4.2% solution) for neonates/small infants.' : 'Use 8.4% solution (1 mEq/mL).',
            max: 'Max 50 mEq'
          };
        }
      }
    ];

    var categoryColors = { cardiac: '#ef4444', metabolic: '#3b82f6', reversal: '#10b981' };
    var categoryLabels = { cardiac: 'Cardiac', metabolic: 'Metabolic', reversal: 'Reversal' };

    // Use event delegation for resus panel
    var resusPanel = document.getElementById('calc-resus');
    if (resusPanel) {
      resusPanel.addEventListener('click', function(e) {
        var btn = e.target.closest('#btn-calc-resus, #btn-clear-resus');
        if (!btn) return;

        if (btn.id === 'btn-clear-resus') {
          var wi = document.getElementById('resus-weight'); if (wi) wi.value = '';
          var rd = document.getElementById('resus-result'); if (rd) { rd.classList.add('hidden'); rd.innerHTML = ''; }
          return;
        }

        // Calculate
        var weightEl = document.getElementById('resus-weight');
        var resultDiv = document.getElementById('resus-result');
        var w = parseFloat(weightEl.value);
        if (!w || w <= 0) { alert('Please enter a valid weight.'); return; }

        var html = '<div style="margin-bottom:12px;font-size:14px;font-weight:700;color:var(--g800);">Doses for ' + w + ' kg patient</div>';
        html += '<div style="display:flex;gap:6px;flex-wrap:wrap;margin-bottom:14px;font-size:11px;">';
        Object.keys(categoryColors).forEach(function(cat) {
          html += '<span style="display:inline-flex;align-items:center;gap:4px;"><span style="width:10px;height:10px;border-radius:50%;background:' + categoryColors[cat] + ';display:inline-block;"></span>' + categoryLabels[cat] + '</span>';
        });
        html += '</div>';
        html += '<div style="display:grid;grid-template-columns:repeat(auto-fill,minmax(300px,1fr));gap:12px;">';

        RESUS_MEDS.forEach(function(med) {
          var r = med.calc(w);
          var color = categoryColors[med.category] || '#6b7280';
          html += '<div style="border:1.5px solid ' + color + '33;border-radius:10px;overflow:hidden;background:#fff;">' +
            '<div style="padding:10px 14px;background:' + color + '0d;border-bottom:1px solid ' + color + '22;">' +
              '<div style="font-size:14px;font-weight:700;color:' + color + ';">' + med.name + '</div>' +
              '<div style="font-size:11px;color:var(--g500);margin-top:2px;">' + med.indication + '</div>' +
            '</div>' +
            '<div style="padding:12px 14px;font-size:13px;">' +
              '<div style="margin-bottom:6px;"><strong>Dose:</strong> ' + r.dose + '</div>' +
              '<div style="margin-bottom:6px;font-size:12px;color:var(--g600);">' + r.extra + '</div>' +
              '<div style="font-size:11px;color:var(--g500);"><strong>Max:</strong> ' + r.max + '</div>' +
              '<div style="font-size:11px;color:var(--g400);margin-top:4px;"><strong>Route:</strong> ' + med.route + '</div>' +
            '</div>' +
          '</div>';
        });

        html += '</div>';
        html += '<div style="margin-top:14px;padding:10px;background:#fef3c7;border-radius:8px;font-size:11px;color:#92400e;">' +
          '<strong>Disclaimer:</strong> Always verify doses against institutional protocols and current guidelines. This tool is for educational reference only.' +
        '</div>';

        resultDiv.innerHTML = html;
        resultDiv.classList.remove('hidden');
      });
    }

    // ═══════════════════════════════════════════════════════════
    // GLASGOW COMA SCALE
    // ═══════════════════════════════════════════════════════════

    // GCS sub-pill navigation
    var gcsPanel = document.getElementById('calc-gcs');
    if (gcsPanel) {
      gcsPanel.addEventListener('click', function(e) {
        var pill = e.target.closest('[data-gcs]');
        if (!pill) return;
        gcsPanel.querySelectorAll('[data-gcs]').forEach(function(p) { p.classList.remove('active'); });
        pill.classList.add('active');
        var isInfant = pill.dataset.gcs === 'infant';
        var childP = document.getElementById('gcs-child-panel');
        var infantP = document.getElementById('gcs-infant-panel');
        if (childP) childP.style.display = isInfant ? 'none' : '';
        if (infantP) infantP.style.display = isInfant ? '' : 'none';
        updateGCS();
      });

      gcsPanel.addEventListener('change', function(e) {
        if (e.target.tagName === 'SELECT') updateGCS();
      });
    }

    function updateGCS() {
      var isInfant = document.querySelector('[data-gcs="infant"].active') !== null;
      var prefix = isInfant ? 'gcs-infant' : 'gcs-child';
      var eye = parseInt(document.getElementById(prefix + '-eye').value) || 0;
      var verbal = parseInt(document.getElementById(prefix + '-verbal').value) || 0;
      var motor = parseInt(document.getElementById(prefix + '-motor').value) || 0;
      var total = eye + verbal + motor;

      var severity, color, bg;
      if (total <= 8)       { severity = 'Severe (Coma)'; color = '#ef4444'; bg = '#fee2e2'; }
      else if (total <= 12) { severity = 'Moderate'; color = '#f59e0b'; bg = '#fef3c7'; }
      else                  { severity = 'Mild'; color = '#10b981'; bg = '#d1fae5'; }

      var resultDiv = document.getElementById('gcs-result');
      if (resultDiv) {
        resultDiv.innerHTML =
          '<div class="calc-result-header" style="background:' + bg + ';border-color:' + color + ';">' +
            '<div style="font-size:24px;font-weight:700;color:' + color + ';">GCS: ' + total + '/15</div>' +
            '<div style="font-size:14px;color:var(--g600);margin-top:4px;">' + severity + '</div>' +
          '</div>' +
          '<div class="calc-result-grid" style="margin-top:12px;">' +
            '<div class="calc-result-item"><div class="calc-result-label">Eye (E)</div><div class="calc-result-value">' + eye + '</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Verbal (V)</div><div class="calc-result-value">' + verbal + '</div></div>' +
            '<div class="calc-result-item"><div class="calc-result-label">Motor (M)</div><div class="calc-result-value">' + motor + '</div></div>' +
          '</div>' +
          '<div style="margin-top:12px;font-size:12px;color:var(--g500);">' +
            '<strong>Interpretation:</strong> 13-15 Mild, 9-12 Moderate, 3-8 Severe/Coma. ' +
            'Intubation typically considered at GCS &le; 8. ' +
            (isInfant ? 'Using infant-modified verbal and motor scales.' : '') +
          '</div>';
      }
    }
    // Initial GCS render
    setTimeout(updateGCS, 200);

    // ═══════════════════════════════════════════════════════════
    // EQUIPMENT SIZING — Harriet Lane Handbook
    // ═══════════════════════════════════════════════════════════

    var EQUIP_DATA = {
      premie: {
        label: 'Premie (1-3 kg)',
        bvm: 'Infant', nasal: '12 Fr', oral: 'Infant', blade: 'Miller 0',
        ett: '2.5-3.0', lma: '1', glidescope: '1',
        iv: '22-24 ga', cvl: '3 Fr', ngt: '5 Fr', chest: '10-12 Fr', foley: '6 Fr'
      },
      newborn: {
        label: 'Newborn (2-4 kg)',
        bvm: 'Infant', nasal: '14-16 Fr', oral: 'Small 50 mm', blade: 'Miller 0',
        ett: '3.0-3.5', lma: '1', glidescope: '1',
        iv: '22-24 ga', cvl: '3-4 Fr', ngt: '5-8 Fr', chest: '10-12 Fr', foley: '6 Fr'
      },
      '6mo': {
        label: '6 months (6-8 kg)',
        bvm: 'Infant', nasal: '14-16 Fr', oral: 'Small 60 mm', blade: 'Miller 1',
        ett: '3.5', lma: '1.5', glidescope: '2',
        iv: '20-24 ga', cvl: '4 Fr', ngt: '8 Fr', chest: '12-18 Fr', foley: '8 Fr'
      },
      '1yr': {
        label: '1 year (10 kg)',
        bvm: 'Small child', nasal: '14-18 Fr', oral: 'Small 60 mm', blade: 'Miller 1 / MAC 2',
        ett: '4.0', lma: '2', glidescope: '2',
        iv: '20-24 ga', cvl: '4-5 Fr', ngt: '10 Fr', chest: '16-20 Fr', foley: '8 Fr'
      },
      '2-3yr': {
        label: '2-3 years (12-16 kg)',
        bvm: 'Small child', nasal: '14-18 Fr', oral: 'Small 70 mm', blade: 'Miller 1 / MAC 2',
        ett: '4.0-4.5', lma: '2', glidescope: '2',
        iv: '18-22 ga', cvl: '4-5 Fr', ngt: '10-12 Fr', chest: '16-24 Fr', foley: '8 Fr'
      },
      '4-6yr': {
        label: '4-6 years (20-25 kg)',
        bvm: 'Child', nasal: '16-20 Fr', oral: 'Small 70-80 mm', blade: 'Miller 2 / MAC 2',
        ett: '4.5-5.0', lma: '2.5', glidescope: '3',
        iv: '18-22 ga', cvl: '5 Fr', ngt: '12-14 Fr', chest: '20-28 Fr', foley: '8 Fr'
      },
      '7-10yr': {
        label: '7-10 years (25-35 kg)',
        bvm: 'Child / Small adult', nasal: '18-22 Fr', oral: 'Medium 80-90 mm', blade: 'Miller 2 / MAC 2',
        ett: '5.5-6.0', lma: '2.5-3', glidescope: '3',
        iv: '18-22 ga', cvl: '5 Fr', ngt: '12-14 Fr', chest: '20-32 Fr', foley: '8 Fr'
      },
      '11-15yr': {
        label: '11-15 years (40-50 kg)',
        bvm: 'Adult', nasal: '22-36 Fr', oral: 'Medium 90 mm', blade: 'Miller 2 / MAC 3',
        ett: '6.0-6.5', lma: '3', glidescope: '3 or 4',
        iv: '18-20 ga', cvl: '7 Fr', ngt: '14-18 Fr', chest: '28-38 Fr', foley: '10 Fr'
      },
      '16yr': {
        label: '16+ years (>50 kg)',
        bvm: 'Adult', nasal: '22-36 Fr', oral: 'Medium 90 mm', blade: 'Miller 2 / MAC 3',
        ett: '7.0-8.0', lma: '4', glidescope: '3 or 4',
        iv: '18-20 ga', cvl: '7 Fr', ngt: '14-18 Fr', chest: '28-42 Fr', foley: '12 Fr'
      }
    };

    var equipPanel = document.getElementById('calc-equipment');
    if (equipPanel) {
      equipPanel.addEventListener('change', function(e) {
        if (e.target.id !== 'equip-age-select') return;
        var key = e.target.value;
        var resultDiv = document.getElementById('equip-result');
        if (!key || !EQUIP_DATA[key]) { resultDiv.classList.add('hidden'); return; }

        var eq = EQUIP_DATA[key];
        resultDiv.classList.remove('hidden');
        resultDiv.innerHTML =
          '<div class="calc-result-header" style="background:#eff6ff;border-color:#2563eb;">' +
            '<div style="font-size:18px;font-weight:700;color:#1d4ed8;">' + eq.label + '</div>' +
          '</div>' +
          '<div style="margin-top:12px;overflow-x:auto;">' +
            '<table class="admin-table" style="font-size:13px;width:100%;">' +
              '<tbody>' +
                '<tr><td style="font-weight:600;width:40%;">Bag-Valve Mask</td><td>' + eq.bvm + '</td></tr>' +
                '<tr><td style="font-weight:600;">Oral Airway</td><td>' + eq.oral + '</td></tr>' +
                '<tr><td style="font-weight:600;">Nasal Airway</td><td>' + eq.nasal + '</td></tr>' +
                '<tr><td style="font-weight:600;">Laryngoscope Blade</td><td>' + eq.blade + '</td></tr>' +
                '<tr><td style="font-weight:600;">ETT Size</td><td>' + eq.ett + '</td></tr>' +
                '<tr><td style="font-weight:600;">LMA Size</td><td>' + eq.lma + '</td></tr>' +
                '<tr><td style="font-weight:600;">Glidescope</td><td>' + eq.glidescope + '</td></tr>' +
                '<tr><td style="font-weight:600;">IV Catheter</td><td>' + eq.iv + '</td></tr>' +
                '<tr><td style="font-weight:600;">Central Line</td><td>' + eq.cvl + '</td></tr>' +
                '<tr><td style="font-weight:600;">NGT / OGT</td><td>' + eq.ngt + '</td></tr>' +
                '<tr><td style="font-weight:600;">Chest Tube</td><td>' + eq.chest + '</td></tr>' +
                '<tr><td style="font-weight:600;">Foley Catheter</td><td>' + eq.foley + '</td></tr>' +
              '</tbody>' +
            '</table>' +
          '</div>' +
          '<div style="margin-top:10px;font-size:11px;color:var(--g400);">' +
            '<strong>ETT Formulas:</strong> Uncuffed = (age/4)+4, Cuffed = (age/4)+3, Depth = ETT size x 3. ' +
            'Source: Harriet Lane Handbook.' +
          '</div>';
      });
    }
  }
})();

// ============================================================
// NEONATAL ASSESSMENT
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-neo-assess' || e.target.closest('#btn-neo-assess')) neoAssess();
  });

  // Fenton 2013 LMS data (weight in grams, GA in weeks)
  var fentonLMS = {
    male: {
      22:{L:0.21,M:496,S:0.17},23:{L:0.21,M:575,S:0.17},24:{L:0.21,M:660,S:0.17},25:{L:0.21,M:762,S:0.16},
      26:{L:0.21,M:870,S:0.16},27:{L:0.20,M:993,S:0.15},28:{L:0.20,M:1124,S:0.15},29:{L:0.19,M:1272,S:0.14},
      30:{L:0.18,M:1430,S:0.14},31:{L:0.17,M:1607,S:0.14},32:{L:0.15,M:1795,S:0.14},33:{L:0.13,M:2008,S:0.13},
      34:{L:0.12,M:2230,S:0.13},35:{L:0.10,M:2467,S:0.13},36:{L:0.08,M:2710,S:0.13},37:{L:0.06,M:2948,S:0.12},
      38:{L:0.04,M:3195,S:0.12},39:{L:0.02,M:3380,S:0.12},40:{L:0.01,M:3530,S:0.12},41:{L:0.00,M:3660,S:0.12},
      42:{L:-0.02,M:3820,S:0.12}
    },
    female: {
      22:{L:0.23,M:474,S:0.17},23:{L:0.22,M:538,S:0.17},24:{L:0.22,M:610,S:0.17},25:{L:0.22,M:705,S:0.16},
      26:{L:0.22,M:810,S:0.16},27:{L:0.21,M:920,S:0.15},28:{L:0.21,M:1040,S:0.15},29:{L:0.20,M:1178,S:0.14},
      30:{L:0.19,M:1330,S:0.14},31:{L:0.18,M:1500,S:0.14},32:{L:0.16,M:1680,S:0.14},33:{L:0.14,M:1880,S:0.13},
      34:{L:0.12,M:2090,S:0.13},35:{L:0.10,M:2310,S:0.13},36:{L:0.08,M:2540,S:0.13},37:{L:0.06,M:2766,S:0.12},
      38:{L:0.04,M:3000,S:0.12},39:{L:0.02,M:3180,S:0.12},40:{L:0.01,M:3340,S:0.12},41:{L:0.00,M:3480,S:0.12},
      42:{L:-0.02,M:3630,S:0.12}
    }
  };

  function interpolateLMS(table, val) {
    var keys = Object.keys(table).map(Number).sort(function(a,b){return a-b;});
    if (val <= keys[0]) return table[keys[0]];
    if (val >= keys[keys.length-1]) return table[keys[keys.length-1]];
    for (var i = 0; i < keys.length - 1; i++) {
      if (val >= keys[i] && val <= keys[i+1]) {
        var t = (val - keys[i]) / (keys[i+1] - keys[i]);
        var a = table[keys[i]], b = table[keys[i+1]];
        return { L: a.L + t*(b.L-a.L), M: a.M + t*(b.M-a.M), S: a.S + t*(b.S-a.S) };
      }
    }
    return table[keys[0]];
  }

  function calcZ(value, L, M, S) {
    if (Math.abs(L) < 0.001) return Math.log(value / M) / S;
    return (Math.pow(value / M, L) - 1) / (L * S);
  }

  function zToPercentile(z) {
    // Approximation of the standard normal CDF
    var a1=0.254829592, a2=-0.284496736, a3=1.421413741, a4=-1.453152027, a5=1.061405429, p=0.3275911;
    var sign = z < 0 ? -1 : 1;
    var x = Math.abs(z) / Math.sqrt(2);
    var t = 1 / (1 + p * x);
    var y = 1 - (((((a5*t + a4)*t) + a3)*t + a2)*t + a1)*t * Math.exp(-x*x);
    return Math.round(((1 + sign * y) / 2) * 1000) / 10;
  }

  function classifyGA(weeks, days) {
    var total = weeks + (days || 0) / 7;
    if (total < 28) return { label: 'Extremely Preterm', color: '#dc2626', icon: 'fa-triangle-exclamation' };
    if (total < 32) return { label: 'Very Preterm', color: '#ea580c', icon: 'fa-triangle-exclamation' };
    if (total < 34) return { label: 'Moderate Preterm', color: '#d97706', icon: 'fa-circle-exclamation' };
    if (total < 37) return { label: 'Late Preterm', color: '#ca8a04', icon: 'fa-circle-info' };
    if (total < 39) return { label: 'Early Term', color: '#2563eb', icon: 'fa-circle-info' };
    if (total < 41) return { label: 'Full Term', color: '#16a34a', icon: 'fa-circle-check' };
    if (total < 42) return { label: 'Late Term', color: '#d97706', icon: 'fa-circle-info' };
    return { label: 'Post Term', color: '#dc2626', icon: 'fa-triangle-exclamation' };
  }

  function classifyWeight(percentile) {
    if (percentile < 3) return { label: 'Severely SGA', color: '#dc2626', detail: '<3rd percentile' };
    if (percentile < 10) return { label: 'SGA', color: '#ea580c', detail: '<10th percentile' };
    if (percentile > 97) return { label: 'Severely LGA', color: '#dc2626', detail: '>97th percentile' };
    if (percentile > 90) return { label: 'LGA', color: '#ea580c', detail: '>90th percentile' };
    return { label: 'AGA', color: '#16a34a', detail: '10th-90th percentile' };
  }

  function classifyBirthWeight(grams) {
    if (grams < 1000) return { label: 'Extremely Low Birth Weight (ELBW)', color: '#dc2626' };
    if (grams < 1500) return { label: 'Very Low Birth Weight (VLBW)', color: '#ea580c' };
    if (grams < 2500) return { label: 'Low Birth Weight (LBW)', color: '#d97706' };
    if (grams <= 4000) return { label: 'Normal Birth Weight', color: '#16a34a' };
    return { label: 'Macrosomia (>4000g)', color: '#ea580c' };
  }

  function neoAssess() {
    var weeks = parseInt(document.getElementById('neo-ga-weeks').value);
    var days = parseInt(document.getElementById('neo-ga-days').value) || 0;
    var weight = parseFloat(document.getElementById('neo-weight').value);
    var sex = document.getElementById('neo-sex').value;
    var resultDiv = document.getElementById('neo-result');

    if (!weeks || !weight) {
      resultDiv.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter GA and birth weight.</p>';
      return;
    }

    var gaDecimal = weeks + days / 7;
    var gaClass = classifyGA(weeks, days);
    var bwClass = classifyBirthWeight(weight);

    // Calculate percentile using Fenton LMS
    var lms = interpolateLMS(fentonLMS[sex], gaDecimal);
    var z = calcZ(weight, lms.L, lms.M, lms.S);
    var percentile = zToPercentile(z);
    var wtClass = classifyWeight(percentile);
    var expectedWeight = Math.round(lms.M);

    var html = '';

    // GA Classification
    html += '<div style="display:flex;gap:12px;flex-wrap:wrap;margin-bottom:12px;">';
    html += '<div style="flex:1;min-width:200px;padding:14px;border-radius:10px;background:' + gaClass.color + '10;border:1.5px solid ' + gaClass.color + '30;">';
    html += '<div style="font-size:12px;color:var(--g500);margin-bottom:4px;">Gestational Age Classification</div>';
    html += '<div style="font-size:18px;font-weight:700;color:' + gaClass.color + ';"><i class="fas ' + gaClass.icon + '"></i> ' + gaClass.label + '</div>';
    html += '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + weeks + ' weeks ' + days + ' days (' + gaDecimal.toFixed(1) + ' weeks)</div>';
    html += '</div>';

    // Weight Classification (AGA/SGA/LGA)
    html += '<div style="flex:1;min-width:200px;padding:14px;border-radius:10px;background:' + wtClass.color + '10;border:1.5px solid ' + wtClass.color + '30;">';
    html += '<div style="font-size:12px;color:var(--g500);margin-bottom:4px;">Weight for Gestational Age</div>';
    html += '<div style="font-size:18px;font-weight:700;color:' + wtClass.color + ';">' + wtClass.label + '</div>';
    html += '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + percentile.toFixed(1) + 'th percentile (' + wtClass.detail + ')</div>';
    html += '</div>';
    html += '</div>';

    // Birth Weight Category
    html += '<div style="display:flex;gap:12px;flex-wrap:wrap;margin-bottom:12px;">';
    html += '<div style="flex:1;min-width:200px;padding:14px;border-radius:10px;background:' + bwClass.color + '10;border:1.5px solid ' + bwClass.color + '30;">';
    html += '<div style="font-size:12px;color:var(--g500);margin-bottom:4px;">Birth Weight Category</div>';
    html += '<div style="font-size:18px;font-weight:700;color:' + bwClass.color + ';">' + bwClass.label + '</div>';
    html += '<div style="font-size:13px;color:var(--g600);margin-top:4px;">' + weight + 'g (' + (weight/1000).toFixed(2) + ' kg)</div>';
    html += '</div>';

    // Stats
    html += '<div style="flex:1;min-width:200px;padding:14px;border-radius:10px;background:var(--g50);border:1.5px solid var(--g200);">';
    html += '<div style="font-size:12px;color:var(--g500);margin-bottom:4px;">Fenton Growth Data (' + (sex === 'male' ? 'Male' : 'Female') + ')</div>';
    html += '<div style="font-size:13px;color:var(--g700);line-height:1.8;">';
    html += '<strong>Expected weight (50th %ile):</strong> ' + expectedWeight + 'g<br>';
    html += '<strong>Z-score:</strong> ' + z.toFixed(2) + '<br>';
    html += '<strong>Percentile:</strong> ' + percentile.toFixed(1) + '%';
    html += '</div></div>';
    html += '</div>';

    // Reference
    html += '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;">Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatrics 2013;13:59. GA classification per ACOG/AAP definitions.</p>';

    resultDiv.innerHTML = html;
  }
})();

// ============================================================
// RESPIRATORY MANAGEMENT (Asthma, Croup, Bronchiolitis)
// ============================================================
(function() {
  // Sub-pill navigation
  document.addEventListener('click', function(e) {
    var pill = e.target.closest('[data-resp]');
    if (pill) {
      document.querySelectorAll('[data-resp]').forEach(function(p) { p.classList.remove('active'); });
      pill.classList.add('active');
      ['asthma','croup','bronchiolitis'].forEach(function(s) {
        var el = document.getElementById('resp-' + s);
        if (el) el.style.display = pill.dataset.resp === s ? '' : 'none';
      });
    }
    if (e.target.closest('[data-asthma-severity]')) asthmaManagement(e.target.closest('[data-asthma-severity]').dataset.asthmaSeverity);
    if (e.target.id === 'btn-pram-calc' || e.target.closest('#btn-pram-calc')) calcPRAM();
    if (e.target.id === 'btn-croup-calc' || e.target.closest('#btn-croup-calc')) calcCroup();
    if (e.target.id === 'btn-bronch-calc' || e.target.closest('#btn-bronch-calc')) calcBronchiolitis();
  });

  function dose(wt, mgPerKg, maxMg) { var d = Math.round(wt * mgPerKg * 10) / 10; return maxMg ? Math.min(d, maxMg) : d; }
  // Delegates to the shared _EM.dStr so the per-kg math is visible to the prescriber.
  function doseStr(wt, mgPerKg, maxMg, unit) {
    return window._EM.dStr(wt, mgPerKg, maxMg, unit);
  }
  function drugRow(name, doseText, route, notes) {
    return '<tr><td style="font-weight:600;">' + name + '</td><td>' + doseText + '</td><td>' + route + '</td><td style="font-size:12px;color:var(--g500);">' + (notes || '') + '</td></tr>';
  }
  function drugTable(rows) {
    return '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;margin:8px 0;"><table style="width:100%;min-width:500px;border-collapse:collapse;font-size:13px;"><thead><tr style="background:var(--g100);"><th style="text-align:left;padding:6px 8px;">Drug</th><th style="padding:6px 8px;">Dose</th><th style="padding:6px 8px;">Route</th><th style="padding:6px 8px;">Notes</th></tr></thead><tbody>' + rows + '</tbody></table></div>';
  }
  function severityBadge(label, color) { return '<span style="display:inline-block;padding:4px 12px;border-radius:6px;background:' + color + '20;color:' + color + ';font-weight:700;font-size:14px;">' + label + '</span>'; }

  function asthmaManagement(severity) {
    var wt = parseFloat(document.getElementById('resp-weight').value);
    var resultDiv = document.getElementById('asthma-result');
    if (!wt) { resultDiv.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }

    var html = '';
    if (severity === 'mild') {
      html += severityBadge('Mild Exacerbation', '#10b981');
      html += '<p style="font-size:13px;margin:8px 0;">Speaks in sentences, no accessory muscle use, SpO2 ≥94%</p>';
      html += drugTable(
        drugRow('Albuterol (MDI)', '4-8 puffs via spacer', 'Inhaled', 'q20min x 3 doses, then q1-4h') +
        drugRow('Albuterol (neb)', doseStr(wt, 0.15, 5, ' mg') + ' (min 2.5 mg)', 'Nebulized', 'q20min x 3 doses') +
        drugRow('Dexamethasone', doseStr(wt, 0.6, 16), 'PO/IV', 'Single dose, or 2 days') +
        drugRow('Prednisolone', doseStr(wt, 1, 60) + '/day', 'PO', 'Alternative: 3-5 day course')
      );
      html += '<div style="margin-top:8px;padding:8px 12px;background:#d1fae5;border-radius:6px;font-size:12px;color:#065f46;"><strong>Reassess after 1 hour.</strong> If improving → discharge with albuterol MDI + spacer + oral steroid course. If not improving → escalate to moderate.</div>';
    } else if (severity === 'moderate') {
      html += severityBadge('Moderate Exacerbation', '#f59e0b');
      html += '<p style="font-size:13px;margin:8px 0;">Speaks in phrases, some accessory muscle use, SpO2 90-93%</p>';
      html += drugTable(
        drugRow('Albuterol (neb)', doseStr(wt, 0.15, 5, ' mg') + ' (min 2.5 mg)', 'Nebulized', 'q20min x 3 doses, then continuous if needed') +
        drugRow('Ipratropium', wt < 20 ? '250 mcg' : '500 mcg', 'Nebulized', 'q20min x 3 doses with albuterol') +
        drugRow('Dexamethasone', doseStr(wt, 0.6, 16), 'PO/IV/IM', 'Single dose') +
        drugRow('O2 supplemental', 'Target SpO2 ≥94%', 'Nasal cannula/mask', 'Titrate to effect')
      );
      html += '<div style="margin-top:8px;padding:8px 12px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;"><strong>Reassess after 1-2 hours.</strong> If improving → step down to mild protocol. If worsening or no improvement → escalate to severe.</div>';
    } else {
      html += severityBadge('Severe / Life-Threatening', '#ef4444');
      html += '<p style="font-size:13px;margin:8px 0;">Speaks in words only, significant accessory muscle use, SpO2 &lt;90%. Consider ICU.</p>';
      html += drugTable(
        drugRow('Albuterol continuous', doseStr(wt, 0.5, 20, ' mg') + '/hr', 'Continuous neb', 'Or 0.15-0.3 mg/kg q20min') +
        drugRow('Ipratropium', wt < 20 ? '250 mcg' : '500 mcg', 'Nebulized', 'q20min x 3 doses with albuterol') +
        drugRow('Dexamethasone', doseStr(wt, 0.6, 16), 'IV', 'Or methylprednisolone 2 mg/kg IV (max 60 mg)') +
        drugRow('Magnesium sulfate', doseStr(wt, 50, 2000) + ' IV over 20 min', 'IV', 'Single dose, monitor BP') +
        drugRow('Epinephrine (IM)', doseStr(wt, 0.01, 0.5) + ' (1:1000)', 'IM', 'If impending arrest / no IV access') +
        drugRow('Terbutaline', doseStr(wt, 0.01, 0.4) + ' SC/IV', 'SC or IV bolus', 'Then 0.1-10 mcg/kg/min infusion') +
        drugRow('O2 supplemental', 'Target SpO2 ≥94%', 'High flow / NIPPV', 'Consider BiPAP/CPAP')
      );
      html += '<div style="margin-top:8px;padding:8px 12px;background:#fee2e2;border-radius:6px;font-size:12px;color:#991b1b;"><strong>Continuous monitoring.</strong> Consider ICU admission. If no response to magnesium → terbutaline infusion. If impending respiratory failure → intubation (ketamine preferred induction agent).</div>';

      // Clinical decision points specific to severe asthma
      html += '<div style="margin-top:10px;display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:8px;">';

      // ABG
      html += '<div style="padding:10px 12px;background:white;border:1px solid var(--g200);border-radius:8px;font-size:12px;line-height:1.5;">' +
        '<div style="font-weight:700;color:var(--blue-dark);margin-bottom:4px;"><i class="fas fa-flask"></i> When to obtain a blood gas</div>' +
        '&bull; Severe exacerbation <strong>not responding</strong> after 1-2 h aggressive therapy<br>' +
        '&bull; Impending respiratory failure — altered mentation, fatigue, silent chest<br>' +
        '&bull; SpO2 &lt;92% despite supplemental O2<br>' +
        '&bull; Suspected CO2 retention (rising PCO2 in a previously tachypneic patient)<br>' +
        '<strong style="color:#991b1b;">Interpretation:</strong> asthmatics hyperventilate → expect <em>low</em> PCO2. A <strong>"normal" or rising PCO2 = impending failure</strong>. Don\'t delay treatment for the gas.' +
        '</div>';

      // Intubation
      html += '<div style="padding:10px 12px;background:white;border:1px solid var(--g200);border-radius:8px;font-size:12px;line-height:1.5;">' +
        '<div style="font-weight:700;color:#dc2626;margin-bottom:4px;"><i class="fas fa-stethoscope"></i> When to intubate (mostly clinical)</div>' +
        '&bull; <strong>Absolute:</strong> apnea, cardiac arrest, coma, inability to protect airway<br>' +
        '&bull; Progressive fatigue despite maximal therapy (NIV, mag, terbutaline, heliox)<br>' +
        '&bull; Refractory hypoxemia / hypercapnia with acidosis<br>' +
        '&bull; Silent chest + deteriorating consciousness<br>' +
        '<strong>RSI choice:</strong> <span style="color:#065f46;font-weight:600;">ketamine 1-2 mg/kg</span> (bronchodilator, preserves BP) + <span style="color:#065f46;font-weight:600;">rocuronium</span>. Avoid succs if hyperkalemic. Permissive hypercapnia after tube; allow expiration (low rate, I:E 1:3-4).' +
        '</div>';

      // Heliox
      html += '<div style="padding:10px 12px;background:white;border:1px solid var(--g200);border-radius:8px;font-size:12px;line-height:1.5;">' +
        '<div style="font-weight:700;color:#7c3aed;margin-bottom:4px;"><i class="fas fa-wind"></i> Heliox (He/O2)</div>' +
        '&bull; Lower gas density → less turbulence → reduced work of breathing through narrowed airways.<br>' +
        '&bull; <strong>Consider in:</strong> severe asthma not responding to max therapy (bridge), upper airway obstruction (croup, post-extubation stridor, FB partial).<br>' +
        '&bull; Typical mix: <strong>70:30 He:O2</strong> (or 80:20). Delivered via tight non-rebreather or in-line with neb.<br>' +
        '&bull; <strong>Limitation:</strong> requires FiO2 ≤ 30-40%. If patient needs higher FiO2, heliox can\'t help.<br>' +
        '&bull; Evidence in asthma is mixed — use as adjunct, not substitute.' +
        '</div>';

      html += '</div>';
    }
    html += '<p style="font-size:11px;color:var(--g400);margin:12px 0 0;">NAEPP/GINA guidelines. Always use clinical judgment. Verify doses against institutional protocols.</p>';
    resultDiv.innerHTML = html;
  }

  function calcPRAM() {
    var total = ['pram-spo2','pram-retractions','pram-scalene','pram-air','pram-wheeze'].reduce(function(s, id) {
      return s + parseInt(document.getElementById(id).value);
    }, 0);
    var severity = total <= 3 ? 'Mild' : total <= 7 ? 'Moderate' : 'Severe';
    var color = total <= 3 ? '#10b981' : total <= 7 ? '#f59e0b' : '#ef4444';
    document.getElementById('pram-result').innerHTML = '<div style="padding:10px 14px;border-radius:8px;background:' + color + '10;border:1.5px solid ' + color + '30;"><span style="font-size:18px;font-weight:700;color:' + color + ';">PRAM Score: ' + total + '/12 — ' + severity + '</span><p style="font-size:12px;color:var(--g600);margin:4px 0 0;">Mild (0-3): outpatient management. Moderate (4-7): consider oral steroids + frequent bronchodilators. Severe (8-12): aggressive treatment, consider ICU.</p></div>';
  }

  function calcCroup() {
    var wt = parseFloat(document.getElementById('resp-weight').value) || 10;
    var total = ['croup-conscious','croup-cyanosis','croup-stridor','croup-air','croup-retractions'].reduce(function(s, id) {
      return s + parseInt(document.getElementById(id).value);
    }, 0);
    var severity, color, treatment;
    if (total <= 2) { severity = 'Mild'; color = '#10b981'; treatment = drugTable(drugRow('Dexamethasone', doseStr(wt, 0.6, 16), 'PO (single dose)', 'Preferred corticosteroid') + drugRow('Supportive care', 'Cool mist, comfort measures', '', 'Discharge if tolerating PO')); }
    else if (total <= 5) { severity = 'Moderate'; color = '#f59e0b'; treatment = drugTable(drugRow('Dexamethasone', doseStr(wt, 0.6, 16), 'PO/IM', 'Single dose') + drugRow('Racemic epinephrine', '0.5 mL of 2.25% solution', 'Nebulized', 'Observe 2-4 hrs after for rebound') + drugRow('Nebulized epinephrine', '0.5 mL/kg of 1:1000 (max 5 mL)', 'Nebulized', 'Alternative to racemic')); }
    else if (total <= 11) { severity = 'Severe'; color = '#ef4444'; treatment = drugTable(drugRow('Dexamethasone', doseStr(wt, 0.6, 16), 'IV/IM', 'Immediate') + drugRow('Racemic epinephrine', '0.5 mL of 2.25% solution', 'Nebulized', 'May repeat q15-20min, observe 2-4 hrs') + drugRow('Nebulized epinephrine', '0.5 mL/kg of 1:1000 (max 5 mL)', 'Nebulized', 'Alternative') + drugRow('Heliox', '70:30 or 80:20', 'Face mask', 'Consider if not responding') + drugRow('O2 supplemental', 'Target SpO2 ≥94%', 'Blow-by preferred', 'Minimize agitation')); }
    else { severity = 'Impending Respiratory Failure'; color = '#dc2626'; treatment = '<div style="padding:10px;background:#fee2e2;border-radius:6px;font-size:13px;color:#991b1b;font-weight:600;">Immediate airway management. Prepare for intubation (use ETT 0.5-1 size smaller than predicted). Call anesthesia/ENT. Continue nebulized epinephrine and dexamethasone IV.</div>'; }

    document.getElementById('croup-result').innerHTML = '<div style="padding:10px 14px;border-radius:8px;background:' + color + '10;border:1.5px solid ' + color + '30;margin-bottom:12px;"><span style="font-size:18px;font-weight:700;color:' + color + ';">Westley Score: ' + total + '/17 — ' + severity + '</span></div>' + treatment + '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;">Westley WJ et al. Nebulized racemic epinephrine by IPPB for the treatment of croup. Am J Dis Child 1978. Mild ≤2, Moderate 3-5, Severe 6-11, Impending failure ≥12.</p>';
  }

  function calcBronchiolitis() {
    var wt = parseFloat(document.getElementById('resp-weight').value) || 5;
    var age = document.getElementById('bronch-age').value;
    var spo2 = document.getElementById('bronch-spo2').value;
    var hydration = document.getElementById('bronch-hydration').value;
    var distress = document.getElementById('bronch-distress').value;

    var html = '<h4 style="font-size:15px;font-weight:700;color:var(--g800);margin:0 0 8px;">Bronchiolitis Management</h4>';
    var admit = distress === 'severe' || spo2 === 'low' || hydration === 'poor' || age === '<12w';

    if (admit) {
      html += severityBadge('Admit / Observe', '#ef4444');
      html += '<div style="margin:10px 0;">';
      if (age === '<12w') html += '<p style="font-size:13px;color:var(--red);font-weight:600;">⚠ Age &lt;12 weeks — high risk for apnea. Monitor closely.</p>';
      html += '</div>';
    } else {
      html += severityBadge('Likely Safe for Discharge', '#10b981');
    }

    html += '<div style="margin:12px 0;"><strong style="font-size:13px;">Supportive Care (evidence-based):</strong></div>';
    html += drugTable(
      drugRow('Nasal suctioning', 'Bulb suction or NasalClear', 'Nasal', 'Before feeds and as needed') +
      drugRow('O2 supplemental', 'Target SpO2 ≥90%', 'NC / high flow', spo2 === 'low' ? 'Required' : 'If needed') +
      drugRow('Hypertonic saline 3%', '4 mL nebulized', 'Nebulized', 'Consider in inpatients (AAP weak recommendation)') +
      (hydration === 'poor' ? drugRow('IV fluids', 'NS/LR bolus ' + doseStr(wt, 20, null, ' mL'), 'IV', 'Then maintenance D5 0.45NS') + drugRow('NG feeds', 'If unable to feed orally', 'NG tube', 'Preferred over IV if gut functional') : '')
    );

    html += '<div style="margin:12px 0;padding:10px 12px;background:var(--amber-light);border-radius:6px;font-size:12px;color:#92400e;"><strong>NOT recommended (AAP 2014/2023):</strong> Albuterol/salbutamol (no benefit in bronchiolitis), epinephrine (no evidence of benefit), systemic corticosteroids (no benefit), antibiotics (unless secondary bacterial infection), chest physiotherapy.</div>';
    html += '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;">AAP Clinical Practice Guideline: Management of Bronchiolitis in Infants and Children (2014, reaffirmed 2023). RSV is the most common cause (50-80%).</p>';
    document.getElementById('bronch-result').innerHTML = html;
  }
})();

// ============================================================
// SEIZURE MANAGEMENT
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-seizure-calc' || e.target.closest('#btn-seizure-calc')) calcSeizure();
  });

  function d(wt, mgPerKg, max) { var v = Math.round(wt * mgPerKg * 100) / 100; return max ? Math.min(v, max) : v; }
  function row(phase, drug, dose, route, notes) {
    return '<tr><td style="font-weight:600;color:var(--blue);">' + phase + '</td><td style="font-weight:600;">' + drug + '</td><td>' + dose + '</td><td>' + route + '</td><td style="font-size:12px;color:var(--g500);">' + notes + '</td></tr>';
  }

  // Visual pathway row — time badge + step card linked by vertical line
  function stepRow(time, color, title, bodyHtml, isLast) {
    return '<div style="display:flex;gap:12px;align-items:stretch;">' +
      '<div style="flex:0 0 auto;width:70px;display:flex;flex-direction:column;align-items:center;">' +
        '<div style="background:' + color + ';color:white;padding:6px 0;border-radius:20px;font-size:12px;font-weight:700;width:60px;text-align:center;box-shadow:0 1px 3px rgba(0,0,0,0.15);">' + time + '</div>' +
        (isLast ? '' : '<div style="flex:1;width:3px;background:' + color + '40;margin:2px 0;"></div>') +
      '</div>' +
      '<div style="flex:1;padding:10px 14px;border-left:4px solid ' + color + ';background:' + color + '10;border-radius:0 8px 8px 0;margin-bottom:' + (isLast ? '4px' : '12px') + ';">' +
        '<div style="font-weight:700;color:' + color + ';font-size:13px;margin-bottom:6px;text-transform:uppercase;letter-spacing:0.3px;">' + title + '</div>' +
        '<div style="font-size:13px;color:var(--g700);line-height:1.55;">' + bodyHtml + '</div>' +
      '</div>' +
    '</div>';
  }

  function calcSeizure() {
    var wt = parseFloat(document.getElementById('seizure-weight').value);
    var resultDiv = document.getElementById('seizure-result');
    if (!wt) { resultDiv.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;
    var d10Low = Math.round(wt * 2 * 10) / 10;
    var d10High = Math.round(wt * 5 * 10) / 10;

    var html = '<div style="padding:10px 14px;border-radius:8px;background:#fee2e2;border:1.5px solid #ef4444;margin-bottom:14px;"><strong style="color:#dc2626;font-size:14px;"><i class="fas fa-bolt"></i> Status Epilepticus Pathway — ' + wt + ' kg</strong><div style="font-size:12px;color:var(--g600);margin-top:3px;">Time = 0 at seizure onset. Do not pause between steps for benzo to take effect — act on the clock.</div></div>';

    // 0 min — STABILIZE
    html += stepRow('0 min', '#3b82f6', 'Stabilize',
      '<strong>ABCs</strong> — position, 100% O2 via NC / NRB, suction. <strong>IV or IO</strong> × 2. Continuous SpO2, ECG, BP. ' +
      '<strong>POC glucose</strong> — if &lt;60 mg/dL: <strong>D10W ' + d10Low + '-' + d10High + ' mL IV</strong> (2-5 mL/kg). ' +
      '<strong>Labs</strong>: CBC, CMP, Mg, Ca, Phos, VBG, lactate, AED levels, toxicology if unclear etiology. ' +
      '<strong>Consider pyridoxine</strong> 100 mg IV in infants &lt;18 mo or INH ingestion. Temperature: treat hyperthermia aggressively.'
    );

    // 5 min — 1ST BENZO
    html += stepRow('5 min', '#8b5cf6', '1st benzodiazepine (give once, pick by access)',
      S.drugTable(
        S.drugRow('Lorazepam <span style="color:#065f46;font-weight:600;">(IV preferred)</span>', S.dStr(wt, 0.1, 4), 'IV / IO', 'Slow push over 1-2 min.') +
        S.drugRow('Midazolam', S.dStr(wt, 0.2, 10), 'IM / IN / buccal', 'Use 5 mg/mL concentrate for IN; split between nares.') +
        S.drugRow('Diazepam', S.dStr(wt, 0.5, 20), 'PR', 'Only if no IV/IM/IN access.')
      )
    );

    // 10 min — 2ND BENZO
    html += stepRow('10 min', '#a855f7', '2nd benzodiazepine — if still seizing',
      'Repeat same agent + dose <strong>once</strong>. Prepare 2nd-line now (don\'t wait to see if benzo works). If apnea/airway compromise: BVM, consider advanced airway.'
    );

    // 20 min — 2ND-LINE
    html += stepRow('20 min', '#f59e0b', '2nd-line anti-epileptic — pick one (ESETT: equivalent efficacy)',
      S.drugTable(
        S.drugRow('Levetiracetam <span style="color:#065f46;font-weight:600;">(preferred)</span>', S.dStr(wt, 60, 4500), 'IV over 5-15 min', 'Best tolerability. No ECG monitoring needed.') +
        S.drugRow('Fosphenytoin', S.dStr(wt, 20, 1500, ' mg PE'), 'IV over 10 min', 'Max rate 3 mg PE/kg/min. Monitor ECG, BP. Avoid if cardiac dysrhythmia.') +
        S.drugRow('Valproic acid', S.dStr(wt, 40, 3000), 'IV over 10 min', '<strong>Avoid &lt;2 yr, hepatic / mitochondrial disease, pregnancy.</strong>') +
        S.drugRow('Phenobarbital', S.dStr(wt, 20, 1000), 'IV over 20 min', 'Last-choice 2nd line. High risk of resp depression + hypotension.')
      )
    );

    // 30 min — 2nd of 2nd-line (optional)
    html += stepRow('30 min', '#ef4444', 'Still seizing? Consider 2nd agent from 2nd-line OR proceed to refractory',
      'If the first 2nd-line drug failed, give a different 2nd-line agent <strong>OR</strong> move directly to refractory therapy. Activate ICU, prepare for intubation. Confirm etiology not reversible (electrolytes, glucose, fever, toxin).'
    );

    // 40 min — REFRACTORY
    html += stepRow('40 min', '#dc2626', 'Refractory status — intubate + continuous infusion + continuous EEG',
      S.drugTable(
        S.drugRow('Midazolam <span style="color:#065f46;font-weight:600;">(1st-line infusion)</span>', 'Bolus ' + d(wt, 0.2, 10) + ' mg → gtt ' + d(wt, 0.05, 2) + '-' + d(wt, 0.5, 18) + ' mg/hr <span style="color:var(--g500);font-size:11px;">(bolus 0.2 mg/kg, gtt 0.05-0.5 mg/kg/hr)</span>', 'IV', 'Titrate to seizure control / burst suppression.') +
        S.drugRow('Pentobarbital', 'Bolus ' + d(wt, 5, 200) + ' mg → gtt ' + d(wt, 1, null) + '-' + d(wt, 5, null) + ' mg/hr <span style="color:var(--g500);font-size:11px;">(bolus 5 mg/kg, gtt 1-5 mg/kg/hr)</span>', 'IV', 'Causes hypotension — often need pressors.') +
        S.drugRow('Propofol', 'Bolus ' + d(wt, 2, 100) + ' mg → gtt ' + d(wt, 2, null) + '-' + d(wt, 5, null) + ' mg/hr <span style="color:var(--g500);font-size:11px;">(bolus 2 mg/kg, gtt 2-5 mg/kg/hr)</span>', 'IV', '<strong>PRIS risk in children</strong> — limit to &lt;4 mg/kg/hr and duration &lt;48 h.') +
        S.drugRow('Ketamine', 'Bolus ' + d(wt, 2, 100) + ' mg → gtt ' + d(wt, 1, null) + '-' + d(wt, 5, null) + ' mg/hr <span style="color:var(--g500);font-size:11px;">(bolus 2 mg/kg, gtt 1-5 mg/kg/hr)</span>', 'IV', 'NMDA antagonist — rescue. Good BP profile; useful if refractory to GABAergics.')
      ) +
      '<div style="margin-top:8px;font-size:12px;color:var(--g600);"><strong>Continuous EEG within 1 h</strong> — target electrographic seizure suppression × 24-48 h, then wean. Reassess etiology: CNS imaging, LP, expanded workup.</div>'
    , true);

    // Key points
    html += '<div style="margin-top:16px;padding:10px 12px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;line-height:1.55;"><strong>Key points</strong><br>' +
      '• Do <strong>NOT</strong> wait for benzo response before starting the 2nd-line — parallel preparation.<br>' +
      '• Maximum <strong>2 benzo doses</strong> total (1 pre-hospital + 1 in ED, or 2 in ED).<br>' +
      '• Respiratory depression is common — have BVM, airway equipment, naloxone, flumazenil accessible (but avoid flumazenil here).<br>' +
      '• ESETT trial: levetiracetam = fosphenytoin = valproate for efficacy. Pick by tolerability / contraindications.<br>' +
      '• Always reassess: ongoing seizure? Non-convulsive status? Pseudo-seizure? → continuous EEG if any doubt.</div>';

    html += '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;font-style:italic;">Based on AES Guidelines 2016 and ESETT (Kapur et al., NEJM 2019). Verify all doses against institutional protocols.</p>';
    resultDiv.innerHTML = html;
  }
})();

// ============================================================
// ANAPHYLAXIS MANAGEMENT
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-anaph-calc' || e.target.closest('#btn-anaph-calc')) calcAnaphylaxis();
  });

  function d(wt, mgPerKg, max) { var v = Math.round(wt * mgPerKg * 100) / 100; return max ? Math.min(v, max) : v; }

  function calcAnaphylaxis() {
    var wt = parseFloat(document.getElementById('anaph-weight').value);
    var age = document.getElementById('anaph-age').value;
    var resultDiv = document.getElementById('anaph-result');
    if (!wt) { resultDiv.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;

    var epiDose = d(wt, 0.01, 0.5);
    var epiVol = Math.round(epiDose * 10) / 10; // 1:1000 = 1 mg/mL
    var autoInjector = wt < 10 ? 'Draw up manually' : wt <= 25 ? 'EpiPen Jr / Auvi-Q 0.15 mg' : 'EpiPen / Auvi-Q 0.3 mg';

    var html = '<div style="padding:14px;border-radius:10px;background:#fee2e2;border:2px solid #ef4444;margin-bottom:16px;">';
    html += '<div style="font-size:18px;font-weight:700;color:#dc2626;margin-bottom:6px;"><i class="fas fa-triangle-exclamation"></i> STEP 1: Epinephrine IM — GIVE IMMEDIATELY</div>';
    html += '<div style="font-size:15px;font-weight:600;color:var(--g800);margin-bottom:4px;">Epinephrine 1:1000 (1 mg/mL): <span style="color:#dc2626;">' + epiDose + ' mg (' + epiVol + ' mL)</span> IM to lateral thigh</div>';
    html += '<div style="font-size:13px;color:var(--g600);">0.01 mg/kg (max 0.5 mg) | Auto-injector: ' + autoInjector + '</div>';
    html += '<div style="font-size:12px;color:#991b1b;margin-top:6px;">May repeat every 5-15 minutes if symptoms persist. No contraindications in anaphylaxis.</div>';
    html += '</div>';

    html += '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;margin-bottom:12px;"><table style="width:100%;min-width:560px;border-collapse:collapse;font-size:13px;"><thead><tr style="background:var(--g100);"><th style="text-align:left;padding:6px 8px;">Step</th><th style="padding:6px 8px;">Drug</th><th style="padding:6px 8px;">Dose</th><th style="padding:6px 8px;">Route</th><th style="padding:6px 8px;">Notes</th></tr></thead><tbody>';

    html += '<tr><td style="font-weight:600;color:var(--blue);">STEP 2</td><td style="font-weight:600;">Position</td><td>Supine + legs elevated</td><td>—</td><td style="font-size:12px;color:var(--g500);">If dyspneic: sitting position. If vomiting: recovery position</td></tr>';
    html += '<tr><td style="font-weight:600;color:var(--blue);">STEP 3</td><td style="font-weight:600;">O2</td><td>High flow 10-15 L/min</td><td>Face mask</td><td style="font-size:12px;color:var(--g500);">100% O2. Prepare for airway management</td></tr>';
    html += '<tr><td style="font-weight:600;color:var(--blue);">STEP 4</td><td style="font-weight:600;">IV fluids</td><td>NS ' + S.dStr(wt, 20, null, ' mL') + ' bolus</td><td>IV/IO</td><td style="font-size:12px;color:var(--g500);">Repeat up to 60 mL/kg for hypotension</td></tr>';
    html += '<tr><td style="font-weight:600;color:var(--blue);">STEP 5</td><td style="font-weight:600;">Diphenhydramine</td><td>' + S.dStr(wt, 1.25, 50) + '</td><td>IV/IM/PO</td><td style="font-size:12px;color:var(--g500);">H1 blocker. NOT first-line — adjunct only</td></tr>';
    html += '<tr><td></td><td style="font-weight:600;">Ranitidine</td><td>' + S.dStr(wt, 1, 50) + '</td><td>IV over 5 min</td><td style="font-size:12px;color:var(--g500);">H2 blocker. Optional adjunct</td></tr>';
    html += '<tr><td style="font-weight:600;color:var(--blue);">STEP 6</td><td style="font-weight:600;">Dexamethasone</td><td>' + S.dStr(wt, 0.6, 16) + '</td><td>IV/IM/PO</td><td style="font-size:12px;color:var(--g500);">Prevents biphasic reaction (4-6 hrs later)</td></tr>';
    html += '<tr><td></td><td style="font-weight:600;">Methylprednisolone</td><td>' + S.dStr(wt, 2, 125) + '</td><td>IV</td><td style="font-size:12px;color:var(--g500);">Alternative steroid</td></tr>';

    html += '<tr style="background:#fef3c7;"><td style="font-weight:600;color:#dc2626;">IF REFRACTORY</td><td style="font-weight:600;">Epinephrine gtt</td><td>0.1-1 mcg/kg/min</td><td>IV infusion</td><td style="font-size:12px;color:var(--g500);">For persistent hypotension despite fluids + IM epi</td></tr>';
    html += '<tr style="background:#fef3c7;"><td></td><td style="font-weight:600;">Glucagon</td><td>' + S.dStr(wt, 0.02, 1) + '</td><td>IV/IM</td><td style="font-size:12px;color:var(--g500);">For patients on beta-blockers not responding to epi</td></tr>';

    html += '</tbody></table></div>';
    html += '<div style="padding:10px 12px;background:var(--amber-light);border-radius:6px;font-size:12px;color:#92400e;"><strong>Observe minimum 4-6 hours</strong> after last dose of epinephrine (biphasic reactions occur in 5-20% of cases). Discharge with EpiPen prescription and anaphylaxis action plan. Refer to allergist.</div>';
    html += '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;">ASCIA Anaphylaxis Guidelines 2021. WAO Anaphylaxis Guidance 2020. AAP/ACAAI Practice Parameters.</p>';
    resultDiv.innerHTML = html;
  }
})();

// ============================================================
// PROCEDURAL SEDATION
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-sed-calc' || e.target.closest('#btn-sed-calc')) calcSedation();
  });

  function d(wt, mgPerKg, max) { var v = Math.round(wt * mgPerKg * 100) / 100; return max ? Math.min(v, max) : v; }

  function calcSedation() {
    var wt = parseFloat(document.getElementById('sed-weight').value);
    var resultDiv = document.getElementById('sed-result');
    if (!wt) { resultDiv.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }

    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--purple-light);border:1.5px solid var(--purple);margin-bottom:12px;"><span style="font-size:14px;font-weight:700;color:var(--purple);">Procedural Sedation — ' + wt + ' kg patient</span></div>';

    // Sedation agents
    html += '<h4 style="font-size:14px;font-weight:700;color:var(--g800);margin:0 0 8px;">Sedation Agents</h4>';
    html += '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;margin-bottom:16px;"><table style="width:100%;min-width:640px;border-collapse:collapse;font-size:13px;"><thead><tr style="background:var(--g100);"><th style="text-align:left;padding:6px 8px;">Drug</th><th style="padding:6px 8px;">Dose</th><th style="padding:6px 8px;">Route</th><th style="padding:6px 8px;">Onset</th><th style="padding:6px 8px;">Duration</th><th style="padding:6px 8px;">Notes</th></tr></thead><tbody>';

    // Small helper: display dose ranges with per-kg footer consistently.
    var perKg = function(lo, hi, unit) {
      unit = unit || 'mg';
      return ' <span style="color:var(--g500);font-size:11px;">(' + lo + (hi != null ? '-' + hi : '') + ' ' + unit + '/kg)</span>';
    };
    html += '<tr><td style="font-weight:600;">Ketamine</td><td>' + d(wt, 1.5, 100) + '-' + d(wt, 2, 150) + ' mg' + perKg(1.5, 2) + '</td><td>IV</td><td>1 min</td><td>15-30 min</td><td style="font-size:12px;color:var(--g500);">Dissociative. Preserves airway reflexes.</td></tr>';
    html += '<tr><td></td><td>' + d(wt, 4, 300) + '-' + d(wt, 5, 400) + ' mg' + perKg(4, 5) + '</td><td>IM</td><td>3-5 min</td><td>30-60 min</td><td style="font-size:12px;color:var(--g500);">Give atropine 0.01 mg/kg to reduce secretions.</td></tr>';
    html += '<tr><td style="font-weight:600;">Midazolam</td><td>' + d(wt, 0.05, 2) + '-' + d(wt, 0.1, 5) + ' mg' + perKg(0.05, 0.1) + '</td><td>IV</td><td>2-3 min</td><td>30-60 min</td><td style="font-size:12px;color:var(--g500);">Anxiolysis. Titrate q3-5 min.</td></tr>';
    html += '<tr><td></td><td>' + d(wt, 0.5, 20) + ' mg' + perKg(0.5, null) + '</td><td>IN/PO</td><td>10-15 min</td><td>30-60 min</td><td style="font-size:12px;color:var(--g500);">IN (max 10 mg / naris) or PO (max 20 mg).</td></tr>';
    html += '<tr><td style="font-weight:600;">Propofol</td><td>' + d(wt, 1, 40) + ' mg' + perKg(1, null) + '</td><td>IV</td><td>30 sec</td><td>5-10 min</td><td style="font-size:12px;color:var(--g500);">Short procedures. Causes apnea — manage airway.</td></tr>';
    html += '<tr><td style="font-weight:600;">Fentanyl</td><td>' + d(wt, 1, 100) + ' mcg' + perKg(1, null, 'mcg') + '</td><td>IV</td><td>2-3 min</td><td>30-60 min</td><td style="font-size:12px;color:var(--g500);">Analgesic. Often combined with midazolam.</td></tr>';
    html += '<tr><td></td><td>' + d(wt, 2, 100) + ' mcg' + perKg(2, null, 'mcg') + '</td><td>IN</td><td>5-10 min</td><td>30-60 min</td><td style="font-size:12px;color:var(--g500);">Intranasal.</td></tr>';
    html += '<tr><td style="font-weight:600;">Nitrous oxide</td><td>50:50 or 70:30 mix</td><td>Inhaled</td><td>2-5 min</td><td>5 min off</td><td style="font-size:12px;color:var(--g500);">Self-administered via demand valve. Anxiolysis + mild analgesia.</td></tr>';
    html += '<tr><td style="font-weight:600;">Dexmedetomidine</td><td>' + d(wt, 2, 100) + ' mcg' + perKg(2, 3, 'mcg') + '</td><td>IN</td><td>15-30 min</td><td>60-90 min</td><td style="font-size:12px;color:var(--g500);">Intranasal. No respiratory depression. Good for imaging.</td></tr>';

    html += '</tbody></table></div>';

    // Reversal agents
    html += '<h4 style="font-size:14px;font-weight:700;color:var(--red);margin:0 0 8px;"><i class="fas fa-rotate-left"></i> Reversal Agents</h4>';
    html += '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;"><table style="width:100%;min-width:560px;border-collapse:collapse;font-size:13px;"><thead><tr style="background:#fee2e2;"><th style="text-align:left;padding:6px 8px;">Drug</th><th style="padding:6px 8px;">Dose</th><th style="padding:6px 8px;">Route</th><th style="padding:6px 8px;">Reverses</th><th style="padding:6px 8px;">Notes</th></tr></thead><tbody>';
    html += '<tr><td style="font-weight:600;">Naloxone</td><td>' + d(wt, 0.1, 2) + ' mg' + perKg(0.1, null) + '</td><td>IV/IM/IN</td><td>Opioids (fentanyl, morphine)</td><td style="font-size:12px;color:var(--g500);">Max 2 mg. Repeat q2-3 min. Duration shorter than opioids — monitor for re-sedation.</td></tr>';
    html += '<tr><td style="font-weight:600;">Flumazenil</td><td>' + d(wt, 0.01, 0.2) + ' mg' + perKg(0.01, null) + '</td><td>IV</td><td>Benzodiazepines (midazolam)</td><td style="font-size:12px;color:var(--g500);">Max 0.2 mg single dose. Repeat q1 min to max 1 mg total. Risk of seizures — use cautiously.</td></tr>';
    html += '</tbody></table></div>';

    html += '<div style="margin-top:12px;padding:10px 12px;background:var(--amber-light);border-radius:6px;font-size:12px;color:#92400e;"><strong>Pre-sedation checklist:</strong> NPO status (2h clear liquids, 6h solids), consent, monitoring equipment (pulse ox, capnography, BP), resuscitation equipment at bedside, suction ready, IV access. Minimum monitoring: continuous SpO2, HR, capnography. Provider capable of managing airway must be present.</div>';
    html += '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;">AAP Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation. ASA Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists.</p>';
    resultDiv.innerHTML = html;
  }
})();

// ============================================================
// IMAGE LIGHTBOX — any element with data-img-src opens fullscreen
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    var opener = e.target.closest && e.target.closest('[data-img-src]');
    if (opener) {
      e.preventDefault();
      var lb = document.getElementById('img-lightbox');
      if (!lb) return;
      var src = opener.dataset.imgSrc;
      var title = opener.dataset.imgTitle || '';
      document.getElementById('img-lightbox-img').src = src;
      document.getElementById('img-lightbox-img').alt = title;
      document.getElementById('img-lightbox-title').textContent = title;
      document.getElementById('img-lightbox-open').href = src;
      lb.style.display = 'flex';
      return;
    }
    // Close on close button, on backdrop click (not on image), and on Escape (below)
    var closeBtn = e.target.closest && e.target.closest('#img-lightbox-close');
    var lb2 = document.getElementById('img-lightbox');
    if (!lb2 || lb2.style.display !== 'flex') return;
    if (closeBtn || e.target === lb2) {
      lb2.style.display = 'none';
      document.getElementById('img-lightbox-img').src = '';
    }
  });
  document.addEventListener('keydown', function(e) {
    if (e.key === 'Escape') {
      var lb = document.getElementById('img-lightbox');
      if (lb && lb.style.display === 'flex') {
        lb.style.display = 'none';
        document.getElementById('img-lightbox-img').src = '';
      }
    }
  });
})();

// ============================================================
// EMERGENCIES SUB-NAV + SHARED HELPERS
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    var pill = e.target.closest('[data-em]');
    if (!pill) return;
    document.querySelectorAll('[data-em]').forEach(function(p) { p.classList.remove('active'); });
    pill.classList.add('active');
    var sections = ['neonatal','airway','cardiac','respiratory','ventilation','seizure','sepsis','anaphylaxis','sedation','agitation','antiemetics','antimicrobials','burns','toxicology','trauma'];
    sections.forEach(function(s) {
      var el = document.getElementById('em-' + s);
      if (el) el.style.display = pill.dataset.em === s ? '' : 'none';
    });
  });
})();

// Shared helpers (attached to window for reuse across sections)
window._EM = {
  d: function(wt, perKg, max) { var v = Math.round(wt * perKg * 100) / 100; return max ? Math.min(v, max) : v; },
  // Dose string — always shows the per-kg used (and max when capped), so the
  // prescriber can verify the math without opening a drug ref.
  //   S.dStr(30, 0.1, 4)        → "3 mg (0.1 mg/kg, max 4 mg)"
  //   S.dStr(60, 0.1, 4)        → "4 mg (0.1 mg/kg, max 4 mg · capped)"
  //   S.dStr(20, 2, 150, ' mcg') → "40 mcg (2 mcg/kg, max 150 mcg)"
  dStr: function(wt, perKg, max, unit) {
    unit = unit || ' mg';
    var uTrim = unit.trim() || 'mg';
    var raw = wt * perKg;
    var v = Math.round(raw * 100) / 100;
    var capped = max != null && v > max;
    var val = capped ? max : v;
    var perKgStr = '(' + perKg + ' ' + uTrim + '/kg';
    if (max != null) perKgStr += ', max ' + max + ' ' + uTrim;
    if (capped) perKgStr += ' · capped';
    perKgStr += ')';
    return val + unit + ' <span style="color:var(--g500);font-size:11px;font-weight:400;">' + perKgStr + '</span>';
  },
  drugTable: function(rows) {
    return '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;margin:8px 0;"><table style="width:100%;min-width:500px;border-collapse:collapse;font-size:13px;"><thead><tr style="background:var(--g100);"><th style="text-align:left;padding:6px 8px;">Drug</th><th style="text-align:left;padding:6px 8px;">Dose</th><th style="text-align:left;padding:6px 8px;">Route</th><th style="text-align:left;padding:6px 8px;">Notes</th></tr></thead><tbody>' + rows + '</tbody></table></div>';
  },
  drugRow: function(name, dose, route, notes) {
    return '<tr><td style="font-weight:600;padding:5px 8px;border-bottom:1px solid var(--g100);">' + name + '</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">' + dose + '</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">' + route + '</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);font-size:12px;color:var(--g500);">' + (notes || '') + '</td></tr>';
  },
  stepBox: function(color, title, body) {
    return '<div style="border-left:4px solid ' + color + ';background:' + color + '10;padding:10px 14px;border-radius:6px;margin-bottom:10px;">' +
           '<div style="font-weight:700;color:' + color + ';font-size:13px;margin-bottom:4px;">' + title + '</div>' +
           '<div style="font-size:13px;color:var(--g700);line-height:1.5;">' + body + '</div></div>';
  },
  arrow: '<div style="text-align:center;color:var(--g400);font-size:16px;margin:-4px 0 6px;">↓</div>',
  badge: function(label, color) { return '<span style="display:inline-block;padding:3px 10px;border-radius:6px;background:' + color + '20;color:' + color + ';font-weight:700;font-size:12px;">' + label + '</span>'; },
  ref: function(text) { return '<p style="font-size:11px;color:var(--g400);margin:8px 0 0;font-style:italic;">' + text + '</p>'; }
};

// ============================================================
// BEDSIDE — AGE → WEIGHT (single source for all sub-sections)
// ============================================================
(function() {
  document.addEventListener('input', function(e) {
    if (e.target && e.target.id === 'bedside-age') recomputeFromAge();
    if (e.target && e.target.id === 'bedside-weight') {
      e.target.dataset.userTyped = '1';
    }
  });
  document.addEventListener('change', function(e) {
    if (e.target && e.target.id === 'bedside-formula') recomputeFromAge(true);
  });
  document.addEventListener('click', function(e) {
    if (e.target.closest && e.target.closest('#btn-bedside-clear')) {
      document.getElementById('bedside-age').value = '';
      var wtField = document.getElementById('bedside-weight');
      wtField.value = '';
      delete wtField.dataset.userTyped;
      var note = document.getElementById('bedside-estimate-note');
      if (note) note.innerHTML = '';
    }
  });

  // Recompute weight from age using the currently selected formula.
  // If forceFromFormula is true (formula dropdown changed), overwrite even user-typed weight.
  function recomputeFromAge(forceFromFormula) {
    var raw = document.getElementById('bedside-age').value;
    var note = document.getElementById('bedside-estimate-note');
    if (!raw || !raw.trim()) { if (note) note.innerHTML = ''; return; }
    var months = window._parseAgeMonths ? window._parseAgeMonths(raw) : null;
    if (months == null || isNaN(months) || months < 0) {
      if (note) note.innerHTML = '<span style="color:var(--red);">Could not parse age. Try "3y", "18 months", "15 days".</span>';
      return;
    }
    var formula = document.getElementById('bedside-formula').value;
    var est = window._PED_MATH.estimateWeightFromAgeMonths(months);
    var pickedWeight = formula === 'bestguess' ? est.all.bestGuess : est.all.apls;
    var pickedLabel = formula === 'bestguess' ? bestGuessBand(months) : aplsBand(months);

    var wtField = document.getElementById('bedside-weight');
    if (forceFromFormula || !wtField.dataset.userTyped) {
      wtField.value = pickedWeight;
      delete wtField.dataset.userTyped;  // treat as computed again
    }
    var ageTxt = months < 12
      ? (Math.round(months * 10) / 10) + ' months'
      : (Math.round(months / 12 * 10) / 10) + ' years';
    if (note) note.innerHTML = '<strong>' + pickedWeight + ' kg</strong> ' +
      '<span style="color:var(--g500);">(' + ageTxt + ', ' + pickedLabel + ')</span> · ' +
      'APLS: ' + est.all.apls + ' kg · Best Guess: ' + est.all.bestGuess + ' kg. <em>You can override the weight field.</em>';
  }

  function aplsBand(m) {
    if (m < 12) return 'APLS 0-12 mo';
    var y = m / 12;
    if (y <= 5) return 'APLS 1-5 yr';
    return 'APLS 6-12 yr';
  }
  function bestGuessBand(m) {
    if (m < 12) return 'Best Guess 1-11 mo';
    var y = m / 12;
    if (y <= 5) return 'Best Guess 1-4 yr';
    return 'Best Guess 5-14 yr';
  }

  // Top bedside weight is estimator-only. Sections have their own weight fields and
  // read them directly (no auto-propagation). No window globals needed here.

  function flash(id) {
    var el = document.getElementById(id);
    if (!el) return;
    var prev = el.style.background;
    el.style.background = 'var(--green)';
    setTimeout(function() { el.style.background = prev; }, 400);
  }
})();

// PED_MATH pure functions now live in /js/calc-math.js (loaded before this file)
// and are available as window._PED_MATH. Sharing the math with Node unit tests.

// ============================================================
// SEPSIS
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-sepsis-show' || e.target.closest('#btn-sepsis-show')) showSepsis();
  });

  function showSepsis() {
    var wt = parseFloat(document.getElementById('sepsis-weight').value);
    var age = document.getElementById('sepsis-age').value;
    var el = document.getElementById('sepsis-result');
    var S = window._EM;
    var html = '';

    var ageLbl = { neonate: 'Neonate (0-28 d)', infant: 'Young infant (29 d - 3 mo)', child: 'Older child / adolescent' }[age];
    html += '<div style="padding:10px 14px;border-radius:8px;background:#fee2e2;border:1.5px solid #ef4444;margin-bottom:12px;"><strong style="color:#dc2626;">Sepsis approach — ' + ageLbl + (wt ? ', ' + wt + ' kg' : '') + '</strong></div>';

    // Definition (Phoenix 2024)
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:0 0 6px;">Definition — Phoenix Sepsis Criteria (JAMA 2024)</h5>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;line-height:1.55;margin-bottom:12px;">';
    html += '<strong>Sepsis</strong> = suspected or confirmed infection + Phoenix Score ≥2 (organ dysfunction across respiratory, cardiovascular, coagulation, neurological).<br>';
    html += '<strong>Septic shock</strong> = sepsis + cardiovascular dysfunction (vasoactive support, or ↑lactate ≥5, or ↓MAP for age).<br>';
    html += '<em style="color:var(--g500);">Previous SIRS-based criteria (Goldstein 2005) are now superseded. Still useful for quick clinical screening.</em>';
    html += '</div>';

    // Quick red flags
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:10px 0 6px;">Red flags (recognize early)</h5>';
    html += '<div style="padding:10px;background:#fef2f2;border-radius:6px;font-size:12px;color:#991b1b;">Abnormal behavior / mentation • Fever + ill-appearance • Tachycardia out of proportion to fever • Prolonged cap refill (&gt;3 s) • Cold/mottled extremities • Weak pulses or wide pulse pressure (&quot;warm shock&quot;) • Hypotension is a <strong>LATE</strong> sign in children • Any immune compromise / indwelling line.</div>';

    // Age-specific approach
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Evaluation &amp; empiric therapy — ' + ageLbl + '</h5>';
    if (age === 'neonate') {
      html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;margin-bottom:10px;">';
      html += '<strong>Workup (full sepsis eval):</strong> CBC + diff, CRP, blood culture, UA + urine culture (cath), <strong>lumbar puncture</strong> (CSF + HSV PCR), CXR if respiratory sx. Consider procalcitonin. Rapid viral panel if available.<br>';
      html += '<strong>Early-onset (&lt;72 h):</strong> GBS, E. coli, Listeria. <strong>Late-onset (&gt;72 h):</strong> coag-neg staph, S. aureus, gram-negs, Candida.</div>';
      html += S.drugTable(
        S.drugRow('Ampicillin', wt ? S.dStr(wt, 100, 2000) : '50-100 mg/kg/dose', 'IV', 'q8-12h depending on age/weight. Covers GBS, Listeria, Enterococcus.') +
        S.drugRow('Gentamicin', wt ? S.dStr(wt, 4, 120) : '4-5 mg/kg/dose', 'IV', 'q24-48h. Monitor levels. Peak 5-12, trough &lt;1.') +
        S.drugRow('Cefotaxime (add)', wt ? S.dStr(wt, 50, 2000) : '50 mg/kg/dose', 'IV', 'If meningitis suspected or gram-neg concern. Ceftriaxone avoided in hyperbilirubinemia.') +
        S.drugRow('Acyclovir', wt ? S.dStr(wt, 20, 1200) : '20 mg/kg/dose', 'IV q8h', 'If HSV risk: maternal genital lesions, vesicles, seizures, CSF pleocytosis, hypothermia, hepatitis.')
      );
    } else if (age === 'infant') {
      html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;margin-bottom:10px;">';
      html += '<strong>Workup:</strong> Use validated rules — PECARN, Aronson, Rochester, Step-by-Step (see below). Most warrant CBC + ANC, procalcitonin and/or CRP, blood culture, UA + urine culture. Many warrant LP + admission + empiric abx.<br>';
      html += '<strong>Coverage:</strong> GBS, E. coli, Listeria (up to ~6 wk), S. pneumoniae, N. meningitidis, H. influenzae, Salmonella.</div>';

      // Febrile-infant rules — collapsible details
      html += '<details style="margin-bottom:10px;border:1px solid var(--g200);border-radius:8px;padding:8px 10px;background:white;"><summary style="cursor:pointer;font-weight:600;font-size:13px;color:var(--blue-dark);"><i class="fas fa-list-check"></i> Validated febrile-infant rules (click to expand)</summary>';
      html += '<div style="margin-top:10px;font-size:12px;line-height:1.55;">';

      // PECARN 2019
      html += '<div style="padding:10px 12px;background:#eff6ff;border-radius:6px;margin-bottom:8px;border-left:4px solid #3b82f6;">';
      html += '<div style="font-weight:700;color:#1e40af;margin-bottom:4px;">PECARN febrile infant rule (Kuppermann et al., JAMA Pediatrics 2019)</div>';
      html += '<strong>Age:</strong> 29-60 days, well-appearing, febrile. <strong>Low-risk if ALL:</strong><br>';
      html += '&nbsp;&bull; Normal UA (no LE, no nitrite, &lt;5 WBC/hpf)<br>';
      html += '&nbsp;&bull; ANC ≤4,090 /&mu;L<br>';
      html += '&nbsp;&bull; Procalcitonin ≤0.5 ng/mL (if procal unavailable: use CRP &le;20 mg/L as proxy)<br>';
      html += '<strong>Low-risk</strong> → may defer LP/abx, observe, close follow-up. <strong>Not low-risk</strong> → full workup + empiric abx.';
      html += '</div>';

      // Aronson 2019
      html += '<div style="padding:10px 12px;background:#f0fdf4;border-radius:6px;margin-bottom:8px;border-left:4px solid #16a34a;">';
      html += '<div style="font-weight:700;color:#166534;margin-bottom:4px;">Aronson rule (Aronson et al., PEDIATRICS 2019)</div>';
      html += '<strong>Age:</strong> 8-60 days, febrile ≥38°C. Point-based score for invasive bacterial infection (IBI):<br>';
      html += '&nbsp;&bull; Age 22-28 days: <strong>+1</strong><br>';
      html += '&nbsp;&bull; Max temperature ≥38.5°C: <strong>+2</strong><br>';
      html += '&nbsp;&bull; ANC ≥5,185 /&mu;L: <strong>+2</strong><br>';
      html += '&nbsp;&bull; Abnormal UA: <strong>+3</strong><br>';
      html += '<strong>Score 0-1</strong> → low risk. <strong>≥2</strong> → consider full workup + abx. Higher scores → higher IBI risk.';
      html += '</div>';

      // Rochester
      html += '<div style="padding:10px 12px;background:#fffbeb;border-radius:6px;margin-bottom:8px;border-left:4px solid #f59e0b;">';
      html += '<div style="font-weight:700;color:#92400e;margin-bottom:4px;">Rochester criteria (Jaskiewicz et al., Pediatrics 1994)</div>';
      html += '<strong>Age:</strong> 0-60 days, febrile. <strong>Low-risk if ALL:</strong><br>';
      html += '&nbsp;&bull; Previously healthy (term, no perinatal complications, no prior abx/hospitalization)<br>';
      html += '&nbsp;&bull; Well-appearing, no focal infection (not skin/bone/joint/soft tissue)<br>';
      html += '&nbsp;&bull; WBC 5,000-15,000 /&mu;L and absolute band count ≤1,500 /&mu;L<br>';
      html += '&nbsp;&bull; UA ≤10 WBC/hpf<br>';
      html += '&nbsp;&bull; If diarrhea: stool ≤5 WBC/hpf<br>';
      html += '<strong>Low-risk</strong> → observation without abx possible (NPV &gt;98%). Does not include procal.';
      html += '</div>';

      // Step-by-Step
      html += '<div style="padding:10px 12px;background:#fdf4ff;border-radius:6px;margin-bottom:4px;border-left:4px solid #a855f7;">';
      html += '<div style="font-weight:700;color:#6b21a8;margin-bottom:4px;">Step-by-Step (Gomez et al., Pediatrics 2016 — European)</div>';
      html += '<strong>Age:</strong> ≤90 days, febrile. Sequential triage; stop at first positive:<br>';
      html += '&nbsp;<strong>1.</strong> Ill-appearing? → <em>high risk</em><br>';
      html += '&nbsp;<strong>2.</strong> Age ≤21 days? → <em>high risk</em><br>';
      html += '&nbsp;<strong>3.</strong> Leukocyturia (UA abnormal)? → <em>high risk</em><br>';
      html += '&nbsp;<strong>4.</strong> Procalcitonin ≥0.5 ng/mL? → <em>high risk</em><br>';
      html += '&nbsp;<strong>5.</strong> CRP &gt;20 mg/L AND/OR ANC &gt;10,000 /&mu;L? → <em>intermediate</em><br>';
      html += '&nbsp;<strong>6.</strong> Otherwise → <em>low risk</em>';
      html += '<div style="margin-top:4px;color:var(--g500);">Highest sensitivity for IBI among these rules when procal available.</div>';
      html += '</div>';

      html += '<div style="margin-top:8px;padding:8px 10px;background:var(--g50);border-radius:6px;font-size:11px;color:var(--g600);"><strong>Practical note:</strong> AAP 2021 Clinical Practice Guideline on the well-appearing febrile infant 8-60 days synthesizes these — ages 8-21 d full workup regardless, 22-28 d inflammatory markers guide LP, 29-60 d UA + markers guide LP/abx. Defer to your local institutional pathway if available.</div>';
      html += '</div></details>';

      html += S.drugTable(
        S.drugRow('Ceftriaxone', wt ? S.dStr(wt, 75, 2000) : '50-75 mg/kg/dose', 'IV / IM', 'q24h (or 100 mg/kg/day divided q12h for meningitis). <strong>Avoid &lt;28 days</strong> if hyperbilirubinemia.') +
        S.drugRow('Ampicillin', wt ? S.dStr(wt, 100, 2000) : '50-100 mg/kg/dose', 'IV', 'If &lt;6 wks: add for Listeria coverage.') +
        S.drugRow('Vancomycin', wt ? S.dStr(wt, 15, 1000) : '15 mg/kg/dose', 'IV', 'If severe / MRSA risk / meningitis. Target trough 15-20.') +
        S.drugRow('Acyclovir', wt ? S.dStr(wt, 20, 1200) : '20 mg/kg/dose', 'IV q8h', '&lt;6 weeks with suspicion of HSV.')
      );
    } else {
      html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;margin-bottom:10px;">';
      html += '<strong>Recognition:</strong> Phoenix score or clinical concern + suspected infection. <strong>Workup:</strong> CBC, CRP, procalcitonin, blood cx (+ site-specific cx), lactate, blood gas, glucose, electrolytes, coags, LP if CNS concern. Source-directed imaging.<br>';
      html += '<strong>Common sources:</strong> respiratory, UTI, CNS, skin/soft tissue, intra-abdominal, bone/joint, indwelling device.</div>';
      html += S.drugTable(
        S.drugRow('Ceftriaxone', wt ? S.dStr(wt, 50, 2000) : '50 mg/kg/dose', 'IV', 'q24h (or 100 mg/kg/day divided for meningitis).') +
        S.drugRow('Vancomycin', wt ? S.dStr(wt, 15, 1000) : '15 mg/kg/dose', 'IV', 'q6h. If severe, indwelling line, or MRSA prevalence &gt;10%.') +
        S.drugRow('Piperacillin-tazobactam', wt ? S.dStr(wt, 100, 4500) : '80-100 mg/kg/dose', 'IV', 'If intra-abdominal / neutropenic.') +
        S.drugRow('Clindamycin', wt ? S.dStr(wt, 10, 900) : '10-13 mg/kg/dose', 'IV', 'Adjunct for toxic shock syndrome (toxin suppression).') +
        S.drugRow('Acyclovir', wt ? S.dStr(wt, 20, 1200) : '10-20 mg/kg/dose', 'IV q8h', 'If HSV CNS concern.')
      );
    }

    // First-hour bundle
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">First-hour bundle (SSC Peds 2020)</h5>';
    html += S.stepBox('#3b82f6', '0-5 min — Recognize', 'Screen for sepsis; sepsis huddle / activation. Assess ABCs. O2 to SpO2 &gt;94%. Warm patient.');
    html += S.stepBox('#8b5cf6', '5-15 min — Access &amp; labs', 'Two IVs or IO. Draw: blood cx (ideally before abx), lactate, CBC, CMP, coags, blood gas, glucose. UA + culture. Source-specific cultures.');
    html += S.stepBox('#f59e0b', '15-30 min — Fluids', (wt ? 'NS or LR <strong>' + S.d(wt, 20) + ' mL</strong> bolus over 5-10 min (20 mL/kg). ' : 'NS/LR 10-20 mL/kg bolus over 5-10 min. ') + 'Reassess after each bolus: HR, perfusion, lung sounds, liver size. Repeat up to 40-60 mL/kg; stop if crackles or hepatomegaly.');
    html += S.stepBox('#10b981', '30-60 min — Antibiotics + reassess', 'Broad-spectrum empiric abx within 1 hour (ideally 3 hr in sepsis, &le;1 hr in septic shock). Recheck lactate, perfusion.');
    html += S.stepBox('#ef4444', '&gt;60 min — Fluid-refractory shock', 'Start vasoactive (<strong>epinephrine 0.05-0.3 mcg/kg/min</strong> for cold shock or <strong>norepinephrine 0.05-0.3 mcg/kg/min</strong> for warm shock). Consider central/IO access. Stress-dose hydrocortisone ' + (wt ? '<strong>' + S.d(wt, 2, 100) + ' mg</strong> IV <span style="color:var(--g500);font-size:11px;">(2 mg/kg, max 100 mg)</span>' : '2 mg/kg IV (max 100 mg)') + ' if catecholamine-resistant. Consider ICU transfer.');

    // Key targets
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Resuscitation targets</h5>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;">Normal mentation • Cap refill ≤2 s • Warm extremities • Strong peripheral pulses • UOP ≥1 mL/kg/hr • MAP ≥5th %ile for age (&gt;65 mmHg adolescent) • SpO2 ≥94% • Lactate trending down.</div>';
    html += S.ref('Phoenix Sepsis Criteria (Schlapbach et al., JAMA 2024). Surviving Sepsis Campaign Pediatric 2020. AAP pediatric sepsis guidance.');
    el.innerHTML = html;
  }
})();

// ============================================================
// NEONATAL RESUSCITATION (NRP) — pathway + drug calc
// ============================================================
(function() {
  document.addEventListener('DOMContentLoaded', renderPathway);
  document.addEventListener('tabChanged', function() { setTimeout(renderPathway, 100); });
  if (document.readyState !== 'loading') setTimeout(renderPathway, 0);

  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-nrp-calc' || e.target.closest('#btn-nrp-calc')) calcNRP();
    // Render NRP pathway when Neonatal sub-pill is clicked (in case component loaded late)
    var np = e.target.closest && e.target.closest('[data-em="neonatal"]');
    if (np) setTimeout(renderPathway, 0);
    var nav = e.target.closest && e.target.closest('[data-calc="bedside"]');
    if (nav) setTimeout(renderPathway, 50);
  });

  function renderPathway() {
    var el = document.getElementById('nrp-pathway-static');
    if (!el || el.dataset.rendered) return;
    var S = window._EM;
    var html = '';
    html += S.stepBox('#3b82f6', 'BIRTH — ASSESS (first 30 sec)', 'Term? Tone? Breathing/crying? If <strong>all yes</strong> → routine care with mother. If <strong>any no</strong> → warm, dry, stimulate, position airway, clear airway PRN, evaluate HR & respirations.');
    html += S.arrow;
    html += S.stepBox('#8b5cf6', 'HR &lt; 100 OR apneic/gasping (60 sec)', '<strong>Start PPV</strong> 40-60 breaths/min, room air for term / 21-30% for preterm. Attach SpO2 (right hand) &plusmn; ECG. MR SOPA if ineffective: <em>M</em>ask adjust, <em>R</em>eposition, <em>S</em>uction, <em>O</em>pen mouth, <em>P</em>ressure increase, <em>A</em>lternative airway.');
    html += S.arrow;
    html += S.stepBox('#f59e0b', 'HR &lt; 100 after 30 sec effective PPV', 'Reassess ventilation — ensure chest rise. Consider increasing FiO2, intubation, or LMA. Continue PPV.');
    html += S.arrow;
    html += S.stepBox('#ef4444', 'HR &lt; 60 after 30 sec of effective PPV', '<strong>Intubate + Chest compressions</strong> — 3:1 ratio (90 compressions + 30 breaths per minute), FiO2 100%, lower 1/3 sternum, depth 1/3 AP chest.');
    html += S.arrow;
    html += S.stepBox('#dc2626', 'HR &lt; 60 despite compressions + PPV x 60 sec', '<strong>Epinephrine</strong> 1:10,000 (0.1 mg/mL): <br>&bull; <strong>IV/IO:</strong> 0.01-0.03 mg/kg (0.1-0.3 mL/kg) — preferred<br>&bull; <strong>ETT:</strong> 0.05-0.1 mg/kg (0.5-1 mL/kg) — while IV being placed<br>Repeat q3-5 min. If hypovolemia: <strong>NS 10 mL/kg IV/IO</strong> over 5-10 min.');
    html += '<div style="display:grid;grid-template-columns:repeat(auto-fit,minmax(160px,1fr));gap:8px;margin-top:14px;">';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;"><strong>Target SpO2 (preductal):</strong><br>1 min: 60-65%<br>2 min: 65-70%<br>3 min: 70-75%<br>4 min: 75-80%<br>5 min: 80-85%<br>10 min: 85-95%</div>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;"><strong>Initial ETT size:</strong><br>&lt;1 kg / &lt;28 wk: <strong>2.5</strong><br>1-2 kg / 28-34 wk: <strong>3.0</strong><br>2-3 kg / 34-38 wk: <strong>3.5</strong><br>&gt;3 kg / &gt;38 wk: <strong>3.5-4.0</strong></div>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;"><strong>ETT depth (lip):</strong><br>~ 6 + weight(kg) cm</div>';
    html += '</div>';
    el.innerHTML = html;
    el.dataset.rendered = '1';
  }

  function calcNRP() {
    var wt = parseFloat(document.getElementById('nrp-weight').value);
    var el = document.getElementById('nrp-result');
    if (!wt) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;
    var epiIvLow = Math.round(wt * 0.01 * 100) / 100;
    var epiIvHigh = Math.round(wt * 0.03 * 100) / 100;
    var epiEtLow = Math.round(wt * 0.05 * 100) / 100;
    var epiEtHigh = Math.round(wt * 0.1 * 100) / 100;
    var ns = Math.round(wt * 10);
    var d10 = Math.round(wt * 2 * 10) / 10;
    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--red)10;border:1.5px solid var(--red);margin-bottom:10px;"><strong style="color:var(--red);">NRP doses — ' + wt + ' kg</strong></div>';
    var pk = function(txt) { return ' <span style="color:var(--g500);font-size:11px;">(' + txt + ')</span>'; };
    html += S.drugTable(
      S.drugRow('Epinephrine 1:10,000', epiIvLow + '-' + epiIvHigh + ' mg, ' + (Math.round(epiIvLow*10)/10) + '-' + (Math.round(epiIvHigh*10)/10) + ' mL' + pk('0.01-0.03 mg/kg = 0.1-0.3 mL/kg'), 'IV / IO', 'Preferred route. Repeat q3-5 min.') +
      S.drugRow('Epinephrine 1:10,000', epiEtLow + '-' + epiEtHigh + ' mg, ' + (Math.round(epiEtLow*10)/10) + '-' + (Math.round(epiEtHigh*10)/10) + ' mL' + pk('0.05-0.1 mg/kg = 0.5-1 mL/kg'), 'ETT', 'While IV being placed.') +
      S.drugRow('Normal saline', ns + ' mL' + pk('10 mL/kg'), 'IV / IO', 'Over 5-10 min for volume. Repeat PRN.') +
      S.drugRow('Dextrose 10%', d10 + ' mL' + pk('2 mL/kg = 0.2 g/kg'), 'IV slow push', 'For documented hypoglycemia. Then D10 infusion 4-6 mg/kg/min.')
    );
    html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;"><strong>Concentration note:</strong> NRP uses epinephrine <strong>1:10,000</strong> (0.1 mg/mL). NOT 1:1000 (1 mg/mL) — that is IM for anaphylaxis / older patients.</div>';
    html += S.ref('AHA/AAP Neonatal Resuscitation Program (NRP) 8th edition, 2020.');
    el.innerHTML = html;
  }
})();

// ============================================================
// AIRWAY / RSI
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-airway-calc' || e.target.closest('#btn-airway-calc')) calcAirway();
  });

  function calcAirway() {
    var wt = parseFloat(document.getElementById('airway-weight').value);
    var age = parseFloat(document.getElementById('airway-age').value);
    var el = document.getElementById('airway-result');
    if (!wt) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;

    // Equipment sizing
    var ettUncuff = age ? Math.round(((age/4) + 4) * 2) / 2 : null;
    var ettCuff = age ? Math.round(((age/4) + 3.5) * 2) / 2 : null;
    var ettDepth = ettUncuff ? Math.round(ettUncuff * 3 * 10) / 10 : null;
    var bladeSize = age != null ? (age < 1 ? 'Miller 0-1' : age < 2 ? 'Miller 1 / Mac 1' : age < 8 ? 'Miller 2 / Mac 2' : 'Miller/Mac 3') : '—';
    var lmaSize = wt < 5 ? '1' : wt < 10 ? '1.5' : wt < 20 ? '2' : wt < 30 ? '2.5' : wt < 50 ? '3' : wt < 70 ? '4' : '5';

    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong style="color:var(--blue-dark);">RSI doses &amp; equipment — ' + wt + ' kg' + (age ? ', ~' + age + ' yr' : '') + '</strong></div>';

    // Pre-medication
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:10px 0 4px;">Pre-medication (optional)</h5>';
    html += S.drugTable(
      S.drugRow('Atropine', S.dStr(wt, 0.02, 1, ' mg') + ' (min 0.1 mg)', 'IV', 'Consider &lt;1 yr or if using succinylcholine, or bradycardia risk') +
      S.drugRow('Lidocaine 2%', S.dStr(wt, 1.5, 100, ' mg'), 'IV over 1 min', 'For ↑ICP, asthma; give 2-3 min pre-induction') +
      S.drugRow('Fentanyl', S.dStr(wt, 2, 150, ' mcg') + ' (2-3 mcg/kg)', 'IV over 1 min', 'Blunts sympathetic response; avoid if hypotensive')
    );

    // Induction
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 4px;">Induction</h5>';
    html += S.drugTable(
      S.drugRow('Ketamine', S.dStr(wt, 1.5, 150, ' mg') + ' (1-2 mg/kg)', 'IV', 'Preserves BP. First-line for shock, asthma, sepsis') +
      S.drugRow('Etomidate', S.dStr(wt, 0.3, 30, ' mg'), 'IV', 'Hemodynamically neutral. Avoid in septic shock (adrenal suppression)') +
      S.drugRow('Propofol', S.dStr(wt, 2, 200, ' mg') + ' (1-2 mg/kg)', 'IV', 'Causes hypotension. Avoid in shock') +
      S.drugRow('Midazolam', S.dStr(wt, 0.2, 10, ' mg'), 'IV', 'Less optimal induction — slower onset')
    );

    // Paralytics
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 4px;">Paralytics</h5>';
    html += S.drugTable(
      S.drugRow('Rocuronium', S.dStr(wt, 1.2, 100, ' mg') + ' (1-1.2 mg/kg)', 'IV', '30-60 sec onset; 30-45 min duration. First-line non-depolarizing.') +
      S.drugRow('Succinylcholine', S.dStr(wt, (wt < 10 ? 2 : 1.5), 150, ' mg'), 'IV', '<10kg: 2 mg/kg; ≥10kg: 1.5 mg/kg. Avoid in burns/crush/hyperK/MH/NM dz. IM option: 4 mg/kg.') +
      S.drugRow('Vecuronium', S.dStr(wt, 0.1, 10, ' mg'), 'IV', '2-3 min onset; longer duration than roc')
    );

    // Post-intubation sedation
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 4px;">Maintenance sedation / analgesia</h5>';
    html += S.drugTable(
      S.drugRow('Midazolam gtt', S.dStr(wt, 0.05, 2, ' mg') + '-' + S.dStr(wt, 0.2, 10, ' mg') + '/hr', 'IV infusion', '0.05-0.2 mg/kg/hr') +
      S.drugRow('Fentanyl gtt', S.dStr(wt, 1, 100, ' mcg') + '-' + S.dStr(wt, 4, 200, ' mcg') + '/hr', 'IV infusion', '1-4 mcg/kg/hr') +
      S.drugRow('Ketamine gtt', S.dStr(wt, 0.5, 30, ' mg') + '-' + S.dStr(wt, 2, 100, ' mg') + '/hr', 'IV infusion', '0.5-2 mg/kg/hr. Good for asthma') +
      S.drugRow('Dexmedetomidine gtt', '0.2-1.4 mcg/kg/hr', 'IV infusion', 'No resp depression; causes bradycardia + hypotension') +
      S.drugRow('Rocuronium gtt', '10-12 mcg/kg/min', 'IV infusion', 'If continued paralysis needed — only with adequate sedation')
    );

    // Equipment
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 4px;">Equipment sizing</h5>';
    html += '<div style="display:grid;grid-template-columns:repeat(auto-fit,minmax(180px,1fr));gap:8px;font-size:12px;">';
    if (age != null) {
      html += '<div style="padding:10px;background:var(--g50);border-radius:6px;"><strong>ETT (uncuffed):</strong> ' + ettUncuff + ' mm<br><strong>ETT (cuffed):</strong> ' + ettCuff + ' mm<br><strong>Depth at lip:</strong> ~' + ettDepth + ' cm</div>';
      html += '<div style="padding:10px;background:var(--g50);border-radius:6px;"><strong>Laryngoscope blade:</strong><br>' + bladeSize + '</div>';
    } else {
      html += '<div style="padding:10px;background:var(--g50);border-radius:6px;"><em>Enter age for ETT/blade sizing.</em><br>ETT (uncuffed) = (age/4) + 4<br>ETT (cuffed) = (age/4) + 3.5<br>Depth = ETT size &times; 3</div>';
    }
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;"><strong>LMA size:</strong> ' + lmaSize + '<br>OPA = corner mouth → angle mandible<br>NPA = tip nose → tragus</div>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;"><strong>Suction catheter (Fr):</strong> ETT size &times; 2<br><strong>NG tube:</strong> ETT &times; 2<br><strong>Chest tube:</strong> 4 &times; ETT</div>';
    html += '</div>';

    // Ventilator starting settings
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 4px;">Ventilator — starting settings</h5>';
    html += '<div style="padding:10px;background:var(--blue-light);border-radius:6px;font-size:12px;color:var(--g700);">';
    html += '<strong>Mode:</strong> Volume or pressure control<br>';
    html += '<strong>Tidal volume:</strong> 6-8 mL/kg (= ' + S.d(wt, 6) + '-' + S.d(wt, 8) + ' mL). Use lower (4-6 mL/kg) for ARDS.<br>';
    html += '<strong>Rate:</strong> Infant 25-30, Child 15-25, Adolescent 12-16<br>';
    html += '<strong>PEEP:</strong> 5 cmH2O (↑ for oxygenation problems)<br>';
    html += '<strong>FiO2:</strong> Start 100%, wean to SpO2 92-97%<br>';
    html += '<strong>I:E ratio:</strong> 1:2 (1:3-4 for obstructive disease)';
    html += '</div>';

    html += S.ref('Harriet Lane Handbook 23rd ed / PALS 2020. Always confirm doses against institutional protocols.');
    el.innerHTML = html;
  }
})();

// ============================================================
// CARDIAC ARREST / PALS
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    var btn = e.target.closest('[data-cardiac]');
    if (btn) cardiacShow(btn.dataset.cardiac);
  });

  function getWt() {
    return parseFloat(document.getElementById('cardiac-weight').value) || 0;
  }

  function cardiacShow(kind) {
    var wt = getWt();
    var el = document.getElementById('cardiac-result');
    if (!wt) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;
    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--red)10;border:1.5px solid var(--red);margin-bottom:10px;"><strong style="color:var(--red);">' + title(kind) + ' — ' + wt + ' kg</strong></div>';

    if (kind === 'general') {
      html += S.drugTable(
        S.drugRow('Epinephrine 1:10,000', S.dStr(wt, 0.01, 1, ' mg') + ' (' + S.dStr(wt, 0.1, 10, ' mL') + ')', 'IV / IO', '0.01 mg/kg = 0.1 mL/kg of 1:10,000. Max single dose 1 mg. Repeat q3-5 min.') +
        S.drugRow('Epinephrine ET', S.dStr(wt, 0.1, 2.5, ' mg'), 'ETT', '0.1 mg/kg (1 mL/kg of 1:10,000) if no IV/IO') +
        S.drugRow('Amiodarone', S.dStr(wt, 5, 300, ' mg'), 'IV / IO bolus', '5 mg/kg for arrest. Max 300 mg. Repeat up to 2 times (max 15 mg/kg/day).') +
        S.drugRow('Lidocaine', S.dStr(wt, 1, 100, ' mg'), 'IV / IO bolus', '1 mg/kg. Alternative to amiodarone for VF/VT.') +
        S.drugRow('Atropine', S.dStr(wt, 0.02, 0.5, ' mg') + ' (min 0.1 mg)', 'IV / IO', '0.02 mg/kg. Bradycardia from ↑vagal tone or AV block.') +
        S.drugRow('Adenosine (1st)', S.dStr(wt, 0.1, 6, ' mg'), 'IV push + flush', '0.1 mg/kg (max 6 mg). For SVT. Rapid push, double flush.') +
        S.drugRow('Adenosine (2nd)', S.dStr(wt, 0.2, 12, ' mg'), 'IV push + flush', '0.2 mg/kg (max 12 mg). Second dose if first unsuccessful.') +
        S.drugRow('Sodium bicarb 8.4%', S.dStr(wt, 1, 50, ' mEq'), 'IV / IO', '1 mEq/kg. ONLY if severe metabolic acidosis, hyperK, or TCA OD. Not routine.') +
        S.drugRow('Calcium chloride 10%', S.dStr(wt, 20, 1000, ' mg') + ' (' + S.dStr(wt, 0.2, 10, ' mL') + ')', 'IV / IO (central preferred)', 'For hyperK, hypoCa, Mg OD, CCB OD. 20 mg/kg = 0.2 mL/kg.') +
        S.drugRow('Calcium gluconate 10%', S.dStr(wt, 60, 3000, ' mg') + ' (' + S.dStr(wt, 0.6, 30, ' mL') + ')', 'IV / IO (peripheral OK)', '60 mg/kg = 0.6 mL/kg. Preferred peripherally.') +
        S.drugRow('Magnesium sulfate', S.dStr(wt, 50, 2000, ' mg'), 'IV over 10-20 min', '25-50 mg/kg. Torsades, severe asthma. Max 2 g.') +
        S.drugRow('Dextrose 10%', S.dStr(wt, 2, null, ' mL') + ' (0.2 g/kg)', 'IV push', 'For documented hypoglycemia') +
        S.drugRow('Defibrillation', '2 J/kg → 4 J/kg → 10 J/kg (max 10 J/kg or adult dose)', 'Pad', 'For VF/pulseless VT. Resume CPR immediately after shock.') +
        S.drugRow('Cardioversion (sync)', '0.5-1 J/kg → 2 J/kg', 'Pad', 'For unstable SVT/VT. Sedate if possible.')
      );
      html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;"><strong>Concentrations:</strong> Epi 1:10,000 (0.1 mg/mL) for IV arrest. 1:1000 (1 mg/mL) for IM anaphylaxis. Atropine &lt;0.1 mg can cause paradoxical bradycardia.</div>';
    } else if (kind === 'asystole') {
      html += S.drugTable(
        S.drugRow('CPR', '100-120/min, depth 1/3 AP', '—', '15:2 (2 rescuer) or 30:2 (single). Rotate every 2 min.') +
        S.drugRow('Epinephrine', S.dStr(wt, 0.01, 1, ' mg') + ' IV/IO', 'IV / IO', '0.01 mg/kg 1:10,000 = 0.1 mL/kg. Q3-5 min. Start early.') +
        S.drugRow('Epinephrine ETT', S.dStr(wt, 0.1, 2.5, ' mg'), 'ETT', '0.1 mg/kg if no IV access')
      );
      html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Reversible causes (H\'s &amp; T\'s)</h5>';
      html += '<div style="display:grid;grid-template-columns:repeat(auto-fit,minmax(160px,1fr));gap:6px;font-size:12px;">';
      html += '<div style="padding:8px;background:var(--g50);border-radius:6px;"><strong>H\'s</strong><br>Hypoxia, Hypovolemia, H+ (acidosis), Hypo/hyperK, Hypoglycemia, Hypothermia</div>';
      html += '<div style="padding:8px;background:var(--g50);border-radius:6px;"><strong>T\'s</strong><br>Tension PTX, Tamponade, Toxins, Thrombosis (MI/PE), Trauma</div>';
      html += '</div>';
    } else if (kind === 'brady') {
      html += S.stepBox('#f59e0b', 'Bradycardia with poor perfusion (HR &lt; 60)', 'Start CPR if HR &lt; 60 with poor perfusion despite oxygenation and ventilation.');
      html += S.arrow;
      html += S.drugTable(
        S.drugRow('Epinephrine', S.dStr(wt, 0.01, 1, ' mg'), 'IV / IO', 'First-line. Q3-5 min.') +
        S.drugRow('Atropine', S.dStr(wt, 0.02, 0.5, ' mg') + ' (min 0.1 mg)', 'IV / IO', 'If ↑ vagal tone or AV block. Max 1 mg child / 0.5 mg infant.') +
        S.drugRow('Transcutaneous pacing', '—', 'Pad', 'For refractory bradycardia not responsive to drugs.') +
        S.drugRow('Consider', '—', '—', 'Hypoxia, tension pneumothorax, ↑ICP, toxic ingestion (organo, CCB, BB), heart block')
      );
    } else if (kind === 'svt') {
      html += S.stepBox('#3b82f6', 'SVT — narrow complex, rate usually &gt;220 infant / &gt;180 child', 'Differentiate from sinus tach: abrupt onset/offset, no P waves or abnormal P axis, HR minimally variable.');
      html += S.arrow;
      html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:6px 0;">If STABLE</h5>';
      html += S.drugTable(
        S.drugRow('Vagal maneuvers', 'Ice to face, blow into syringe, Valsalva', '—', 'Try first in stable patient') +
        S.drugRow('Adenosine (1st)', S.dStr(wt, 0.1, 6, ' mg'), 'IV push (proximal) + flush', 'Rapid push, 3-way stopcock with NS flush') +
        S.drugRow('Adenosine (2nd)', S.dStr(wt, 0.2, 12, ' mg'), 'IV push + flush', 'If first dose unsuccessful') +
        S.drugRow('Procainamide', '15 mg/kg over 30-60 min', 'IV', 'Expert consult. Avoid with amiodarone.') +
        S.drugRow('Amiodarone', '5 mg/kg over 20-60 min', 'IV', 'Expert consult.')
      );
      html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:10px 0 4px;">If UNSTABLE</h5>';
      html += S.drugTable(S.drugRow('Synchronized cardioversion', '0.5-1 J/kg → 2 J/kg', 'Pad', 'Sedate if possible. Pre-treat with adenosine if IV available.'));
    } else if (kind === 'vfib') {
      html += S.stepBox('#dc2626', 'VF / Pulseless VT', 'High-quality CPR + defibrillation are key. Minimize interruptions.');
      html += S.arrow;
      html += S.drugTable(
        S.drugRow('Defibrillation (1st)', '2 J/kg', 'Pad', 'Resume CPR immediately after shock.') +
        S.drugRow('Defibrillation (2nd)', '4 J/kg', 'Pad', 'After 2 min CPR.') +
        S.drugRow('Defibrillation (3rd+)', '≥4 J/kg (max 10 J/kg or adult dose)', 'Pad', '') +
        S.drugRow('Epinephrine', S.dStr(wt, 0.01, 1, ' mg'), 'IV / IO', 'After 2nd shock. Q3-5 min.') +
        S.drugRow('Amiodarone', S.dStr(wt, 5, 300, ' mg'), 'IV / IO bolus', 'Refractory VF/VT. Max 15 mg/kg/day.') +
        S.drugRow('Lidocaine', S.dStr(wt, 1, 100, ' mg'), 'IV / IO', 'Alternative to amiodarone. Then 20-50 mcg/kg/min gtt.') +
        S.drugRow('Mg sulfate', S.dStr(wt, 50, 2000, ' mg'), 'IV over 1-2 min', 'For torsades or hypoMg.')
      );
    } else if (kind === 'vt') {
      html += S.stepBox('#f59e0b', 'Stable monomorphic VT', 'Expert consult. Avoid combining QT-prolonging agents.');
      html += S.arrow;
      html += S.drugTable(
        S.drugRow('Amiodarone', '5 mg/kg over 20-60 min', 'IV', '= ' + S.d(wt, 5, 300) + ' mg over 20-60 min') +
        S.drugRow('Procainamide', '15 mg/kg over 30-60 min', 'IV', 'Do not combine with amiodarone') +
        S.drugRow('Sync cardioversion', '0.5-1 → 2 J/kg', 'Pad', 'If becomes unstable. Sedate.')
      );
    }
    html += S.ref('AHA PALS Guidelines 2020. Always verify against institutional protocols.');
    el.innerHTML = html;
  }

  function title(k) {
    return { general: 'PALS General Doses', asystole: 'Asystole / PEA', brady: 'Bradycardia', svt: 'SVT', vfib: 'VF / Pulseless VT', vt: 'Stable VT' }[k] || k;
  }
})();

// ============================================================
// AGITATION
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-agit-calc' || e.target.closest('#btn-agit-calc')) calcAgit();
  });

  function calcAgit() {
    var wt = parseFloat(document.getElementById('agit-weight').value);
    var el = document.getElementById('agit-result');
    if (!wt) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;
    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--purple-light);border:1.5px solid var(--purple);margin-bottom:10px;"><strong style="color:var(--purple);">Agitation management — ' + wt + ' kg</strong></div>';
    html += S.stepBox('#10b981', 'Step 1 — Non-pharmacologic', 'Dim lights, quiet room, familiar caregiver present, reduce stimulation. Rule out hypoglycemia, hypoxia, pain, ↑ICP, toxic ingestion, infection.');
    html += S.stepBox('#3b82f6', 'Step 2 — Oral / intranasal (cooperative)', 'First-line for moderate agitation if the patient will accept PO/IN.');
    html += S.drugTable(
      S.drugRow('Lorazepam', S.dStr(wt, 0.05, 2, ' mg'), 'PO', '0.05 mg/kg. May repeat in 30 min.') +
      S.drugRow('Midazolam', S.dStr(wt, 0.5, 10, ' mg'), 'PO', '0.5 mg/kg (max 10 mg)') +
      S.drugRow('Midazolam', S.dStr(wt, 0.3, 10, ' mg'), 'IN (5 mg/mL)', '0.3 mg/kg split between nares (max 10 mg)') +
      S.drugRow('Olanzapine (ODT)', wt < 30 ? '2.5-5 mg' : '5-10 mg', 'PO / ODT', 'Age ≥6 yr. Avoid IM + benzo combo (risk of resp depression).') +
      S.drugRow('Diphenhydramine', S.dStr(wt, 1, 50, ' mg'), 'PO', '1 mg/kg. Adjunct only; sedating.')
    );
    html += S.stepBox('#f59e0b', 'Step 3 — IM / IV (severe, uncooperative, or safety risk)', 'Require continuous monitoring. Consider restraints only as last resort.');
    html += S.drugTable(
      S.drugRow('Midazolam', S.dStr(wt, 0.1, 5, ' mg'), 'IV / IM', '0.05-0.1 mg/kg IV, 0.1-0.15 mg/kg IM (max 10 mg)') +
      S.drugRow('Lorazepam', S.dStr(wt, 0.1, 4, ' mg'), 'IV / IM', '0.05-0.1 mg/kg (max 4 mg). May cause resp depression.') +
      S.drugRow('Haloperidol', wt < 40 ? '0.025-0.075 mg/kg = ' + S.d(wt, 0.05) + ' mg' : '2.5-5 mg', 'IM / IV', 'Avoid &lt;3 yr. Risk: QT, EPS, NMS. ECG if repeated.') +
      S.drugRow('Olanzapine', wt < 40 ? '2.5-5 mg' : '5-10 mg', 'IM', 'Avoid benzo co-administration (resp depression, hypotension)') +
      S.drugRow('Ketamine', S.dStr(wt, 4, 500, ' mg'), 'IM', '4-5 mg/kg IM (rescue for severe excited delirium). Monitor airway.') +
      S.drugRow('Droperidol', '0.03-0.07 mg/kg = ' + S.d(wt, 0.05) + ' mg', 'IM / IV', 'Effective but QT concern — get ECG.')
    );
    html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;"><strong>Monitoring:</strong> Continuous SpO2 + HR after parenteral sedation. Have airway equipment, flumazenil, naloxone, and IV access ready.</div>';
    html += S.ref('AAP Clinical Report on Pediatric Agitation. ACEP Guidelines for Acute Agitation.');
    el.innerHTML = html;
  }
})();

// ============================================================
// ANTIEMETICS
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-emet-calc' || e.target.closest('#btn-emet-calc')) calcEmet();
  });

  function calcEmet() {
    var wt = parseFloat(document.getElementById('emet-weight').value);
    var el = document.getElementById('emet-result');
    if (!wt) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    var S = window._EM;
    // Ondansetron weight bands
    var ondWt = wt < 15 ? '2 mg' : wt < 30 ? '4 mg' : '8 mg';
    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong style="color:var(--blue-dark);">Antiemetic doses — ' + wt + ' kg</strong></div>';
    html += S.drugTable(
      S.drugRow('Ondansetron', ondWt + ' (weight band) OR ' + S.dStr(wt, 0.15, 8, ' mg') + ' (0.15 mg/kg)', 'PO / ODT / IV', 'First-line. Max single 8 mg. Repeat q8h. QT prolongation — avoid with other QT drugs. &lt;6 mo: limited data.') +
      S.drugRow('Metoclopramide', S.dStr(wt, 0.15, 10, ' mg'), 'IV / IM / PO', '0.1-0.15 mg/kg (max 10 mg). Give with diphenhydramine to prevent EPS / dystonia.') +
      S.drugRow('Dimenhydrinate', S.dStr(wt, 1.25, 50, ' mg'), 'PO / IV / IM / PR', '1.25 mg/kg (max 50 mg) q6h. ≥2 yr.') +
      S.drugRow('Diphenhydramine', S.dStr(wt, 1, 50, ' mg'), 'PO / IV / IM', '1 mg/kg (max 50 mg) q6h. Adjunct, sedating.') +
      S.drugRow('Promethazine', S.dStr(wt, 0.25, 25, ' mg'), 'PO / IV / IM', '0.25-1 mg/kg. <strong>CONTRAINDICATED &lt;2 yr</strong> (resp depression). Tissue injury if IV extrav.') +
      S.drugRow('Dexamethasone', S.dStr(wt, 0.15, 10, ' mg'), 'IV / PO', 'Adjunct, esp. chemo-induced. 0.15 mg/kg (max 10 mg).') +
      S.drugRow('Scopolamine patch', '1.5 mg patch', 'Transdermal', '≥12 yr. Motion sickness. Apply 4h before exposure.')
    );
    html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;"><strong>Pearls:</strong> Ondansetron is first-line in ED for acute gastroenteritis vomiting — single PO/ODT dose increases oral rehydration success. Avoid anticholinergics + opioid combinations. Check QTc if stacking ondansetron + other QT drugs.</div>';
    html += S.ref('AAP gastroenteritis guidance; WHO essential medicines; Lexicomp.');
    el.innerHTML = html;
  }
})();

// ============================================================
// ANTIMICROBIALS (empiric, by age + infection type)
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-abx-lookup' || e.target.closest('#btn-abx-lookup')) lookupAbx();
  });

  var REG = {
    neonate: {
      sepsis: { first: 'Ampicillin + gentamicin', alt: 'Add cefotaxime if meningitis suspected or gram-neg concern', duration: '7-10 days; 21 days if confirmed meningitis', notes: 'Cover GBS, E. coli, Listeria. Add acyclovir if HSV risk (maternal lesions, vesicles, seizures).' },
      meningitis: { first: 'Ampicillin + cefotaxime (or gentamicin) + acyclovir', alt: 'Add vancomycin if gram-positive cocci', duration: '14-21 days depending on organism', notes: 'HSV coverage essential. LP + HSV PCR.' },
      pna: { first: 'Ampicillin + gentamicin', alt: 'Add cefotaxime for gram-neg', duration: '7-10 days', notes: 'Same as sepsis coverage.' },
      uti: { first: 'Ampicillin + gentamicin', alt: 'Cefotaxime if sensitivities known', duration: '10-14 days', notes: 'Evaluate for sepsis. Renal US and VCUG workup.' },
      skin: { first: 'Ampicillin + gentamicin', alt: 'Add vancomycin if MRSA risk', duration: '7-10 days', notes: 'Omphalitis, mastitis — broad coverage.' },
      ent: { first: 'Discuss with infectious diseases', alt: '—', duration: '—', notes: 'Rare in neonates. Any ear/throat infection warrants sepsis eval.' },
      neutropenic: { first: 'Cefepime or piperacillin-tazobactam', alt: 'Add vancomycin if indwelling line, severe mucositis, or MRSA', duration: 'Until ANC recovery + afebrile ≥48h', notes: 'Oncology/ID consult.' },
      ic: { first: 'Ampicillin + gentamicin + metronidazole', alt: 'Or piperacillin-tazobactam', duration: '7-14 days', notes: 'NEC: add metronidazole/clindamycin for anaerobes.' },
      bone: { first: 'Ampicillin + gentamicin', alt: 'Vancomycin if MRSA risk', duration: '3-6 weeks (IV then PO)', notes: 'Usually hematogenous. S. aureus, GBS, E. coli.' }
    },
    infant: {
      sepsis: { first: 'Ampicillin + ceftriaxone (or gentamicin)', alt: '+ vancomycin if MRSA / severe', duration: '7-10 days', notes: 'Add acyclovir if HSV suspected (<6 wks). Fever in <90 days requires workup.' },
      meningitis: { first: 'Ceftriaxone + vancomycin (± ampicillin if &lt;6 wks for Listeria)', alt: '+ acyclovir if HSV', duration: '10-14 days (longer for Listeria/gram-neg)', notes: 'Dexamethasone if H. influenzae suspected.' },
      pna: { first: 'Ampicillin (or ceftriaxone)', alt: 'Add azithromycin if atypical', duration: '7-10 days', notes: 'S. pneumoniae most common. RSV/viral often primary.' },
      uti: { first: 'Ceftriaxone or cefotaxime', alt: 'Ampicillin + gentamicin', duration: '10-14 days', notes: 'US kidney/bladder if first febrile UTI.' },
      skin: { first: 'Cefazolin or clindamycin', alt: 'Vancomycin if MRSA risk', duration: '7-10 days', notes: 'Consider MRSA if purulent or local resistance >10%.' },
      ent: { first: 'Amoxicillin (90 mg/kg/day) for AOM', alt: 'Amox-clav if recent abx/treatment failure', duration: 'AOM 10 days &lt;2 yr; 7 days ≥2 yr', notes: 'Observe mild AOM if &gt;6 mo and no severe features.' },
      neutropenic: { first: 'Cefepime or piperacillin-tazobactam', alt: '+ vancomycin for severe/mucositis/line', duration: 'Until ANC recovery + afebrile', notes: 'Oncology/ID consult.' },
      ic: { first: 'Ceftriaxone + metronidazole', alt: 'Piperacillin-tazobactam', duration: '5-7 days (uncomplicated), longer for complicated', notes: 'Appendicitis — surgical consult.' },
      bone: { first: 'Cefazolin ± vancomycin', alt: 'Clindamycin', duration: '3-4 weeks (IV then PO transition)', notes: 'S. aureus most common. Kingella in &lt;4 yr.' }
    },
    child: {
      sepsis: { first: 'Ceftriaxone + vancomycin', alt: 'Piperacillin-tazobactam if intra-abdominal', duration: '7-14 days', notes: 'Expand if specific source. Add antifungal if prolonged neutropenia.' },
      meningitis: { first: 'Ceftriaxone + vancomycin', alt: '+ dexamethasone (Hib coverage)', duration: '10-14 days', notes: 'Lumbar puncture. Dexamethasone 0.15 mg/kg q6h x 4 days.' },
      pna: { first: 'Ampicillin OR amoxicillin (high dose)', alt: 'Ceftriaxone if hospitalized; add azithromycin for atypical', duration: '5-7 days (uncomplicated)', notes: 'Mycoplasma if &gt;5 yr. Consider viral causes.' },
      uti: { first: 'Cephalexin or TMP-SMX (PO)', alt: 'Ceftriaxone if ill', duration: '7-10 days (10-14 if pyelo)', notes: 'Culture-guided de-escalation.' },
      skin: { first: 'Cephalexin or clindamycin', alt: 'TMP-SMX or doxycycline if MRSA', duration: '5-10 days', notes: 'Abscess — incision &amp; drainage primary tx.' },
      ent: { first: 'Amoxicillin 90 mg/kg/day (AOM); Penicillin V for strep pharyngitis', alt: 'Amox-clav; cephalexin if non-anaphylactic PCN allergy', duration: 'AOM 5-10 days; strep 10 days', notes: 'Strep pharyngitis dose: PCN V 250 mg BID-TID (&lt;27 kg) or 500 mg BID (≥27 kg).' },
      neutropenic: { first: 'Cefepime OR piperacillin-tazobactam', alt: '+ vancomycin', duration: 'Until ANC recovery + afebrile', notes: 'Add empiric antifungal if fever &gt;4-7 days.' },
      ic: { first: 'Ceftriaxone + metronidazole', alt: 'Piperacillin-tazobactam', duration: '5-7 days (uncomplicated appendicitis)', notes: 'Surgical consult.' },
      bone: { first: 'Cefazolin ± vancomycin', alt: 'Clindamycin', duration: '3-4 weeks total', notes: 'S. aureus, group A strep. Consider MRSA if severe.' }
    }
  };

  function lookupAbx() {
    var age = document.getElementById('abx-age').value;
    var inf = document.getElementById('abx-infection').value;
    var el = document.getElementById('abx-result');
    var r = REG[age] && REG[age][inf];
    if (!r) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">No regimen found.</p>'; return; }
    var S = window._EM;
    var ageLbl = { neonate: 'Neonate (0-28 d)', infant: 'Infant (1-3 mo)', child: 'Child (>3 mo)' }[age];
    var infLbl = document.querySelector('#abx-infection option[value="' + inf + '"]').textContent;
    var html = '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong style="color:var(--blue-dark);">' + ageLbl + ' — ' + infLbl + '</strong></div>';
    html += '<div style="padding:12px;background:#d1fae5;border-radius:6px;margin-bottom:10px;"><strong style="color:#065f46;">First-line:</strong> ' + r.first + '</div>';
    html += '<div style="padding:12px;background:var(--g50);border-radius:6px;margin-bottom:10px;"><strong>Alternative / add:</strong> ' + r.alt + '</div>';
    html += '<div style="padding:12px;background:var(--g50);border-radius:6px;margin-bottom:10px;"><strong>Duration:</strong> ' + r.duration + '</div>';
    html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;"><strong>Notes:</strong> ' + r.notes + '</div>';
    html += S.ref('AAP Red Book, IDSA guidelines, Harriet Lane. Always tailor to local resistance patterns and culture results.');
    el.innerHTML = html;
  }
})();

// ============================================================
// BURNS — Lund-Browder body parts + Parkland
// ============================================================
(function() {
  // Lund-Browder age-adjusted region percentages. Regions marked "*" change with age.
  // Column order: infant, young (1-5), child (5-10), adol (10-15), adult (>15).
  var LB = {
    head:      { label: 'Head',                vals: [18, 13, 11, 9, 7],    ageSensitive: true },
    neck:      { label: 'Neck',                vals: [2, 2, 2, 2, 2] },
    ant_trunk: { label: 'Anterior trunk',      vals: [13, 13, 13, 13, 13] },
    post_trunk:{ label: 'Posterior trunk',     vals: [13, 13, 13, 13, 13] },
    r_buttock: { label: 'Right buttock',       vals: [2.5, 2.5, 2.5, 2.5, 2.5] },
    l_buttock: { label: 'Left buttock',        vals: [2.5, 2.5, 2.5, 2.5, 2.5] },
    genital:   { label: 'Genitalia',           vals: [1, 1, 1, 1, 1] },
    r_uparm:   { label: 'R upper arm',         vals: [4, 4, 4, 4, 4] },
    l_uparm:   { label: 'L upper arm',         vals: [4, 4, 4, 4, 4] },
    r_forearm: { label: 'R forearm',           vals: [3, 3, 3, 3, 3] },
    l_forearm: { label: 'L forearm',           vals: [3, 3, 3, 3, 3] },
    r_hand:    { label: 'R hand',              vals: [2.5, 2.5, 2.5, 2.5, 2.5] },
    l_hand:    { label: 'L hand',              vals: [2.5, 2.5, 2.5, 2.5, 2.5] },
    r_thigh:   { label: 'R thigh',             vals: [5.5, 8, 8.5, 9, 9.5],  ageSensitive: true },
    l_thigh:   { label: 'L thigh',             vals: [5.5, 8, 8.5, 9, 9.5],  ageSensitive: true },
    r_leg:     { label: 'R lower leg',         vals: [5, 5.5, 6, 6.5, 7],    ageSensitive: true },
    l_leg:     { label: 'L lower leg',         vals: [5, 5.5, 6, 6.5, 7],    ageSensitive: true },
    r_foot:    { label: 'R foot',              vals: [3.5, 3.5, 3.5, 3.5, 3.5] },
    l_foot:    { label: 'L foot',              vals: [3.5, 3.5, 3.5, 3.5, 3.5] }
  };
  var AGE_KEYS = ['infant','young','child','adol','adult'];

  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-burn-calc' || e.target.closest('#btn-burn-calc')) calcBurn();
    if (e.target.id === 'btn-burn-reset' || e.target.closest('#btn-burn-reset')) resetParts();
    // Render body-parts table the first (or any) time the Burns sub-pill is activated
    var bp = e.target.closest && e.target.closest('[data-em="burns"]');
    if (bp) setTimeout(renderBodyParts, 0);
    // Also render if the top-level Bedside tab is clicked (ensures table ready before user navigates)
    var nav = e.target.closest && e.target.closest('[data-calc="bedside"]');
    if (nav) setTimeout(renderBodyParts, 50);
  });
  document.addEventListener('change', function(e) {
    if (e.target && e.target.id === 'burn-age') renderBodyParts();
  });
  document.addEventListener('input', function(e) {
    if (e.target && e.target.dataset && e.target.dataset.burnRegion) updateLive();
  });
  // Also attempt render on these events in case component mounts later
  document.addEventListener('DOMContentLoaded', renderBodyParts);
  document.addEventListener('tabChanged', function() { setTimeout(renderBodyParts, 100); });
  if (document.readyState !== 'loading') setTimeout(renderBodyParts, 0);

  function ageIdx() { return Math.max(0, AGE_KEYS.indexOf(document.getElementById('burn-age').value)); }

  function renderBodyParts() {
    var wrap = document.getElementById('burn-bodyparts-wrapper');
    if (!wrap) return;
    var idx = ageIdx();
    var html = '<div style="background:var(--g50);border-radius:8px;padding:10px 12px;">';
    html += '<div style="font-size:12px;color:var(--g600);margin-bottom:8px;line-height:1.4;">For each involved body region, enter <strong>% of that region burned (2° or deeper)</strong>. Leave 0 if uninvolved. TBSA = sum of (region size × % involvement).</div>';
    html += '<div style="display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));gap:6px;">';
    Object.keys(LB).forEach(function(key) {
      var r = LB[key];
      var max = r.vals[idx];
      var isAgeDep = r.ageSensitive;
      html += '<div style="display:flex;align-items:center;gap:8px;padding:4px 8px;background:white;border-radius:6px;border:1px solid var(--g200);">' +
              '<label style="flex:1;font-size:12px;color:var(--g700);">' + r.label + ' <span style="color:var(--g400);">(' + max + '%' + (isAgeDep ? '<span title="age-adjusted">*</span>' : '') + ')</span></label>' +
              '<input type="number" min="0" max="100" step="5" value="0" data-burn-region="' + key + '" data-burn-max="' + max + '" style="width:68px;padding:3px 6px;border:1px solid var(--g300);border-radius:4px;font-size:12px;text-align:right;"> %' +
              '</div>';
    });
    html += '</div></div>';
    wrap.innerHTML = html;
    updateLive();
  }

  function resetParts() {
    var inputs = document.querySelectorAll('[data-burn-region]');
    inputs.forEach(function(i) { i.value = 0; });
    document.getElementById('burn-tbsa').value = '';
    updateLive();
  }

  function computeTbsa() {
    var idx = ageIdx();
    var total = 0;
    Object.keys(LB).forEach(function(key) {
      var el = document.querySelector('[data-burn-region="' + key + '"]');
      if (!el) return;
      var pct = parseFloat(el.value) || 0;
      if (pct < 0) pct = 0; if (pct > 100) pct = 100;
      total += LB[key].vals[idx] * (pct / 100);
    });
    return Math.round(total * 10) / 10;
  }

  function updateLive() {
    var t = computeTbsa();
    var live = document.getElementById('burn-tbsa-live');
    if (live) live.textContent = t > 0 ? 'Computed TBSA: ' + t + '%' : '';
  }

  function calcBurn() {
    var wt = parseFloat(document.getElementById('burn-weight').value);
    var override = document.getElementById('burn-tbsa').value;
    var tbsa = override !== '' ? parseFloat(override) : computeTbsa();
    var el = document.getElementById('burn-result');
    if (!wt) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter weight (kg).</p>'; return; }
    if (!tbsa || tbsa <= 0) { el.innerHTML = '<p style="color:var(--red);font-size:13px;">Enter % involvement per region, or override TBSA.</p>'; return; }
    var S = window._EM;
    var total = Math.round(4 * wt * tbsa);
    var first8 = Math.round(total / 2);
    var rateFirst = Math.round(first8 / 8);
    var next16 = total - first8;
    var rateNext = Math.round(next16 / 16);
    var maint = wt <= 10 ? wt * 4 : wt <= 20 ? 40 + (wt - 10) * 2 : 60 + (wt - 20);
    maint = Math.round(maint);

    var html = '<div style="padding:10px 14px;border-radius:8px;background:#fee2e2;border:1.5px solid #ef4444;margin-bottom:10px;"><strong style="color:#dc2626;">Burn fluid resuscitation — ' + wt + ' kg, ' + tbsa + '% TBSA (2° or deeper)</strong></div>';
    html += '<div style="padding:12px;background:#fef2f2;border-radius:6px;margin-bottom:10px;"><strong>Parkland formula:</strong> 4 mL × kg × %TBSA = <strong>' + total + ' mL LR over 24 hours</strong>' +
            '<br>&nbsp;&nbsp;<strong>First 8 h</strong> (from time of burn): ' + first8 + ' mL (~<strong>' + rateFirst + ' mL/hr</strong>)' +
            '<br>&nbsp;&nbsp;<strong>Next 16 h</strong>: ' + next16 + ' mL (~<strong>' + rateNext + ' mL/hr</strong>)</div>';
    html += '<div style="padding:12px;background:var(--g50);border-radius:6px;margin-bottom:10px;"><strong>Plus maintenance fluids (4-2-1):</strong> ' + maint + ' mL/hr (D5 1/2NS ± 20 mEq KCl/L once UOP established). Consider dextrose in children &lt;30 kg.</div>';
    html += '<div style="padding:12px;background:var(--g50);border-radius:6px;margin-bottom:10px;"><strong>Titrate to UOP:</strong> target 1-2 mL/kg/hr (infants / children), 0.5-1 mL/kg/hr (adolescents). <strong>Clinical response trumps formula.</strong></div>';

    // Breakdown of what regions contributed
    var idx = ageIdx();
    var breakdown = '';
    Object.keys(LB).forEach(function(key) {
      var el = document.querySelector('[data-burn-region="' + key + '"]');
      if (!el) return;
      var pct = parseFloat(el.value) || 0;
      if (pct > 0) {
        var contrib = Math.round(LB[key].vals[idx] * pct / 100 * 10) / 10;
        breakdown += '<div>' + LB[key].label + ': ' + pct + '% of ' + LB[key].vals[idx] + '% = ' + contrib + '%</div>';
      }
    });
    if (breakdown) {
      html += '<details style="margin-bottom:10px;"><summary style="cursor:pointer;font-size:13px;font-weight:600;color:var(--g700);">Region breakdown</summary><div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;margin-top:6px;">' + breakdown + '</div></details>';
    }

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Other pearls</h5>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;">';
    html += '<strong>Rule of palm:</strong> Patient\'s palm + fingers ≈ 1% TBSA — good for scattered burns.<br>';
    html += '<strong>First-degree burns DO NOT count</strong> toward TBSA or Parkland.<br>';
    html += '<strong>Analgesia:</strong> Morphine 0.05-0.1 mg/kg IV q2h, or fentanyl 1-2 mcg/kg IV q30-60 min.<br>';
    html += '<strong>Tetanus</strong> prophylaxis if indicated. Tdap/Td ± tetanus immunoglobulin.';
    html += '</div>';

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Burn center referral (ABA)</h5>';
    html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;">Partial-thickness &gt;10% TBSA; any full-thickness; face/hands/feet/genital/perineum/major joints; electrical/chemical/inhalation; associated trauma; significant comorbidities; pediatric burns in non-pediatric center.</div>';
    html += S.ref('ABA Advanced Burn Life Support (ABLS) 2018. Parkland formula: Baxter 1968. Lund-Browder 1944 chart (age-adjusted regions).');
    el.innerHTML = html;
  }
})();

// ============================================================
// TOXICOLOGY
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-tox-lookup' || e.target.closest('#btn-tox-lookup')) lookupTox();
  });

  function lookupTox() {
    var wt = parseFloat(document.getElementById('tox-weight').value);
    var topic = document.getElementById('tox-topic').value;
    var el = document.getElementById('tox-result');
    var S = window._EM;
    var html = '';

    if (topic === 'approach') {
      html += S.stepBox('#3b82f6', '1. Stabilize (ABCDE)', 'Airway, breathing, circulation, disability (glucose, pupils, GCS), exposure. Naloxone if depressed LOC + resp depression. Dextrose if hypoglycemic. Thiamine in select cases.');
      html += S.stepBox('#8b5cf6', '2. Identify toxidrome', '<strong>Sympathomimetic:</strong> HTN, tachy, mydriasis, diaphoresis (cocaine, meth). <strong>Anticholinergic:</strong> hot/dry, mydriasis, tachy, delirium (antihistamines, TCAs). <strong>Cholinergic:</strong> SLUDGE-M, miosis (organophosphates). <strong>Opioid:</strong> miosis, resp depression, ↓LOC. <strong>Sedative-hypnotic:</strong> ↓LOC, normal/low vitals.');
      html += S.stepBox('#f59e0b', '3. Decontamination', '<strong>Activated charcoal</strong> 1 g/kg PO (max 50 g): within 1h of ingestion, intact airway, ingestion adsorbed (not Li, metals, alcohols). Avoid caustics/hydrocarbons. <strong>Whole bowel irrigation:</strong> PEG for metals/iron/lithium/sustained release. <strong>Gastric lavage:</strong> rarely indicated. <strong>Ipecac:</strong> no longer recommended.');
      html += S.stepBox('#10b981', '4. Enhance elimination', '<strong>Urinary alkalinization</strong> (salicylates, phenobarbital). <strong>Hemodialysis</strong> (see ISTUMBLE). <strong>Lipid emulsion</strong> for lipid-soluble drug toxicity (LA, CCB, TCA).');
      html += S.stepBox('#ef4444', '5. Antidotes', 'See topic list. <strong>Contact Poison Center</strong> (US: 1-800-222-1222) early for any significant exposure.');
    } else if (topic === 'acetaminophen') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Acetaminophen overdose</strong></div>';
      html += '<p style="font-size:13px;">Acute toxic dose: &gt;150 mg/kg (or 7.5 g total) single ingestion. Hepatotoxic after 24h; AST/ALT peak day 3-4.</p>';
      html += '<p style="font-size:13px;"><strong>Diagnosis:</strong> Draw level at 4h post-ingestion (or on arrival if &gt;4h). Plot on <strong>Rumack-Matthew nomogram</strong> (treatment line at 150 mcg/mL at 4h).</p>';
      html += S.drugTable(
        S.drugRow('N-acetylcysteine (NAC) — IV', '150 mg/kg over 1h → 50 mg/kg over 4h → 100 mg/kg over 16h (21h total)', 'IV', 'Total 300 mg/kg. Most effective if started &lt;8h post-ingestion.') +
        S.drugRow('N-acetylcysteine — PO', '140 mg/kg load, then 70 mg/kg q4h × 17 doses', 'PO', 'Alternative to IV. Unpleasant taste — often with juice.') +
        S.drugRow('Activated charcoal', '1 g/kg (max 50 g)', 'PO', 'If within 1-2h of ingestion and airway protected.')
      );
      if (wt) html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;"><strong>For ' + wt + ' kg:</strong> IV loading = ' + S.d(wt, 150) + ' mg over 1h <span style="color:var(--g500);font-size:11px;">(150 mg/kg)</span>; 2nd bag = ' + S.d(wt, 50) + ' mg over 4h <span style="color:var(--g500);font-size:11px;">(50 mg/kg)</span>; 3rd bag = ' + S.d(wt, 100) + ' mg over 16h <span style="color:var(--g500);font-size:11px;">(100 mg/kg)</span>. <em>Total 300 mg/kg.</em></div>';
    } else if (topic === 'opioids') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Opioid overdose</strong></div>';
      html += '<p style="font-size:13px;">Triad: <strong>miosis + respiratory depression + ↓ LOC</strong>. Fentanyl / synthetics may require repeated/higher doses.</p>';
      html += S.drugTable(
        S.drugRow('Naloxone (initial)', '0.01-0.1 mg/kg' + (wt ? ' = ' + S.d(wt, 0.01) + '-' + S.d(wt, 0.1) + ' mg' : ''), 'IV / IM / IN / IO', 'Start low if chronic opioid use (avoid withdrawal). Titrate to respiratory effort, not consciousness.') +
        S.drugRow('Naloxone (full reversal)', '2 mg IV/IM/IN', 'IV / IM / IN', 'If no chronic use and severe resp depression. Repeat q2-3 min.') +
        S.drugRow('Naloxone infusion', '2/3 of effective bolus per hour', 'IV', 'For long-acting opioids (methadone, fentanyl patch, sustained release)')
      );
      html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;">Observe ≥4h after last dose; longer for long-acting agents. Duration of naloxone (30-90 min) is shorter than most opioids — <strong>re-sedation is common</strong>.</div>';
    } else if (topic === 'iron') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Iron overdose</strong></div>';
      html += '<p style="font-size:13px;">Toxic dose: elemental Fe ≥20 mg/kg. Severe ≥60 mg/kg. <strong>Charcoal does NOT bind iron.</strong></p>';
      html += '<p style="font-size:13px;"><strong>Stages:</strong> 1) GI (0-6h: vomiting, bloody diarrhea); 2) Latent (6-24h: deceptive improvement); 3) Shock/metabolic acidosis (12-24h); 4) Hepatotoxicity (2-5d); 5) Gastric scarring (2-8 wk).</p>';
      html += S.drugTable(
        S.drugRow('Whole bowel irrigation', 'PEG-ES 25-40 mL/kg/hr', 'NG', 'For radiopaque pills on KUB or ingested sustained-release iron.') +
        S.drugRow('Deferoxamine', '15 mg/kg/hr IV infusion', 'IV', 'Max 6-8 g/day. Indications: shock, metabolic acidosis, Fe level &gt;500 mcg/dL, or severe symptoms. Urine turns "vin rosé" color.')
      );
      html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;">Iron level at 4-6h. &lt;350 usually asymptomatic; 350-500 mild; &gt;500 severe. Consider KUB for radiopaque pills.</div>';
    } else if (topic === 'tca') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>TCA overdose</strong></div>';
      html += '<p style="font-size:13px;">Anticholinergic + Na-channel blockade. <strong>Risks:</strong> seizure, VT/VF, hypotension, coma. ECG: QRS &gt;100 ms or R in aVR &gt;3 mm predicts toxicity.</p>';
      html += S.drugTable(
        S.drugRow('Sodium bicarbonate 8.4%', '1-2 mEq/kg IV bolus → infusion', 'IV', 'Goal pH 7.45-7.55 and narrowing QRS. Repeat bolus for QRS widening, hypotension, or arrhythmia.') +
        S.drugRow('Mg sulfate', S.dStr(wt || 30, 50, 2000, ' mg'), 'IV over 10 min', 'For torsades.') +
        S.drugRow('IV lipid emulsion 20%', '1.5 mL/kg bolus → 0.25 mL/kg/min × 30-60 min', 'IV', 'If refractory shock/arrest. Consult toxicology.')
      );
      html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;"><strong>Avoid</strong> Class IA/IC antiarrhythmics, beta-blockers, physostigmine (risk of asystole with TCAs).</div>';
    } else if (topic === 'bbccb') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>β-blocker / Calcium-channel blocker overdose</strong></div>';
      html += '<p style="font-size:13px;">Bradycardia + hypotension. CCBs (esp. verapamil, diltiazem, amlodipine) can be lethal in small pediatric doses.</p>';
      html += S.drugTable(
        S.drugRow('IV fluids', '20 mL/kg NS bolus', 'IV', 'Cautious — avoid volume overload') +
        S.drugRow('Calcium chloride 10% or gluconate', 'CaCl 20 mg/kg / Ca-glu 60 mg/kg', 'IV', 'First-line for CCB. Repeat q15-20 min.') +
        S.drugRow('Glucagon', '50 mcg/kg IV bolus → 50-150 mcg/kg/hr', 'IV', 'β-blocker antidote. GI side effects common.') +
        S.drugRow('High-dose insulin (HIE)', 'Regular insulin 1 U/kg bolus → 0.5-2 U/kg/hr + D25% infusion', 'IV', 'Hyperinsulinemic euglycemia therapy. Monitor K+ and glucose closely.') +
        S.drugRow('Vasopressors', 'Epi / norepi infusion', 'IV', 'Titrate to MAP.') +
        S.drugRow('Lipid emulsion 20%', '1.5 mL/kg → 0.25 mL/kg/min', 'IV', 'For lipid-soluble CCBs (verapamil) if refractory.') +
        S.drugRow('Methylene blue / ECMO', '—', '—', 'Rescue therapy — toxicology/ICU consult.')
      );
    } else if (topic === 'benzo') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Benzodiazepine overdose</strong></div>';
      html += '<p style="font-size:13px;">Sedation + resp depression. Usually supportive — intubation rarely needed alone. <strong>Flumazenil caution.</strong></p>';
      html += S.drugTable(
        S.drugRow('Flumazenil', '0.01 mg/kg (max 0.2 mg) IV, may repeat q1 min to max 1 mg', 'IV', 'Only for iatrogenic reversal in a benzo-naive patient with no TCAs, seizure disorder, or chronic benzo use. <strong>Can precipitate seizures.</strong>')
      );
      html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;">In real-world ingestion, <strong>supportive care (airway, monitoring)</strong> is usually safer than flumazenil.</div>';
    } else if (topic === 'organo') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Organophosphate / carbamate poisoning</strong></div>';
      html += '<p style="font-size:13px;">Cholinergic toxidrome: <strong>SLUDGE-M</strong> (salivation, lacrimation, urination, defecation, GI distress, emesis, miosis) + muscle fasciculation, bradycardia, bronchorrhea. Decontamination critical (PPE for providers).</p>';
      html += S.drugTable(
        S.drugRow('Atropine', '0.05 mg/kg IV, double q3-5 min until bronchial secretions dry', 'IV', 'Endpoint = dry lungs, not dry mouth or heart rate. Can require huge doses.') +
        S.drugRow('Pralidoxime (2-PAM)', '25-50 mg/kg IV over 30 min (max 2 g) → 10-20 mg/kg/hr', 'IV', 'Only for organophosphates (not carbamates). Regenerates acetylcholinesterase.') +
        S.drugRow('Diazepam / midazolam', 'Standard seizure doses', 'IV', 'For seizures or severe fasciculations.')
      );
    } else if (topic === 'salicylate') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Salicylate overdose</strong></div>';
      html += '<p style="font-size:13px;">Mixed respiratory alkalosis + anion gap metabolic acidosis. Tinnitus, tachypnea, diaphoresis, hyperthermia. Severe: CNS depression, seizures, pulmonary edema, cerebral edema.</p>';
      html += S.drugTable(
        S.drugRow('Fluids', 'Aggressive resuscitation', 'IV', 'Dehydration common. Avoid fluid overload (risk of pulmonary edema).') +
        S.drugRow('Sodium bicarb', '1-2 mEq/kg IV bolus → drip', 'IV', 'Urinary alkalinization (goal urine pH &gt;7.5). Prevents CNS entry.') +
        S.drugRow('Glucose', 'Maintain euglycemia even if BG normal', 'IV', 'CNS hypoglycemia despite normal serum glucose.') +
        S.drugRow('Hemodialysis', '—', '—', 'For severe: altered MS, pulmonary edema, renal failure, refractory acidosis, or level &gt;100 mg/dL acute / &gt;60 chronic.')
      );
    } else if (topic === 'etoh') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Toxic alcohols (methanol / ethylene glycol)</strong></div>';
      html += '<p style="font-size:13px;">Anion gap metabolic acidosis + osmolar gap. Methanol → visual changes, blindness. Ethylene glycol → calcium oxalate crystals in urine, renal failure.</p>';
      html += S.drugTable(
        S.drugRow('Fomepizole', '15 mg/kg IV load → 10 mg/kg q12h × 4 → 15 mg/kg q12h', 'IV', 'First-line. Inhibits alcohol dehydrogenase.') +
        S.drugRow('Ethanol (alternative)', 'Load 600 mg/kg → maintain level 100-150 mg/dL', 'IV / PO', 'If fomepizole unavailable. Monitor closely.') +
        S.drugRow('Hemodialysis', '—', '—', 'For severe acidosis, end-organ damage, or high levels.') +
        S.drugRow('Folate / thiamine / pyridoxine', 'Standard doses', 'IV', 'Methanol: folate. EG: thiamine + pyridoxine (divert to non-toxic metabolites).')
      );
    } else if (topic === 'dialyzable') {
      html += '<div style="padding:10px 14px;border-radius:8px;background:var(--blue-light);border:1.5px solid var(--blue);margin-bottom:10px;"><strong>Dialyzable drugs (ISTUMBLE)</strong></div>';
      html += '<p style="font-size:13px;">Commonly dialyzable in overdose:</p>';
      html += '<div style="display:grid;grid-template-columns:repeat(auto-fit,minmax(200px,1fr));gap:6px;font-size:13px;">';
      [['I','Isopropyl alcohol, INH'],['S','Salicylates'],['T','Theophylline, Toxic alcohols'],['U','Uremia-related drugs'],['M','Methanol, Metformin, Methotrexate'],['B','Barbiturates (long-acting)'],['L','Lithium'],['E','Ethylene glycol']].forEach(function(x) {
        html += '<div style="padding:8px 10px;background:var(--g50);border-radius:6px;"><strong>' + x[0] + ':</strong> ' + x[1] + '</div>';
      });
      html += '</div>';
      html += '<div style="padding:10px;background:#fef3c7;border-radius:6px;font-size:12px;color:#92400e;margin-top:10px;"><strong>Poor candidates for HD:</strong> Large Vd (TCAs, digoxin, BBs), highly protein-bound (benzos, CCBs), lipid-soluble (opioids, phenothiazines). EXTRIP recommendations are evidence-based — consult toxicology.</div>';
    }
    html += S.ref('Call Poison Control early: 1-800-222-1222 (US). Refs: Goldfrank\'s Toxicologic Emergencies, EXTRIP workgroup.');
    el.innerHTML = html;
  }
})();

// ============================================================
// TRAUMA
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-trauma-show' || e.target.closest('#btn-trauma-show')) showTrauma();
  });

  function showTrauma() {
    var wt = parseFloat(document.getElementById('trauma-weight').value);
    var el = document.getElementById('trauma-result');
    var S = window._EM;
    var html = '';

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:0 0 6px;">Primary Survey — ABCDE</h5>';
    html += S.stepBox('#ef4444', 'A — Airway + c-spine', 'Maintain airway (jaw thrust, suction). <strong>Manual inline stabilization</strong>; apply collar. Intubate if GCS ≤8, inadequate airway, or impending compromise. Avoid succinylcholine if burn/crush/prolonged immobilization.');
    html += S.stepBox('#f59e0b', 'B — Breathing', 'SpO2, bilateral breath sounds, chest wall integrity. Identify tension PTX (needle decompression), open PTX (3-sided dressing), flail chest, massive hemothorax.');
    html += S.stepBox('#10b981', 'C — Circulation', 'Two large-bore IVs / IO. Control hemorrhage (direct pressure, tourniquet, pelvic binder). ' + (wt ? 'NS or LR 20 mL/kg = ' + S.d(wt, 20) + ' mL bolus.' : 'NS/LR 20 mL/kg bolus.') + ' Consider blood after 40-60 mL/kg crystalloid or in Class III shock.');
    html += S.stepBox('#3b82f6', 'D — Disability', 'GCS, pupils, glucose, gross motor. Consider ↑ICP (head up 30°, mannitol 0.5-1 g/kg or hypertonic saline 3% 3-5 mL/kg).');
    html += S.stepBox('#8b5cf6', 'E — Exposure + environment', 'Fully expose; prevent hypothermia (warm blankets, fluids).');

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:16px 0 6px;">Massive Transfusion Protocol (MTP)</h5>';
    html += S.drugTable(
      S.drugRow('Ratio', '1:1:1 (pRBC : FFP : platelets)', '—', 'Activate early if ≥40 mL/kg transfused or ongoing hemorrhage. Avoid excessive crystalloid.') +
      S.drugRow('Tranexamic acid (TXA)', '15 mg/kg IV (max 1 g) over 10 min → 2 mg/kg/hr × 8h', 'IV', 'Within 3 hr of injury. CRASH-2 / MATIC.') +
      S.drugRow('Calcium', '20 mg/kg CaCl or 60 mg/kg Ca-gluconate IV per unit citrated blood', 'IV', 'Citrated blood chelates calcium.')
    );

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:16px 0 6px;">C-spine clearance (NEXUS / CCR)</h5>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;">Pediatric c-spine decision tools are imperfect. <strong>Imaging if any:</strong> focal neurologic deficit, altered mental status, neck pain / tenderness, torticollis, substantial torso injury, high-risk mechanism (diving, MVC &gt;55 mph, fall &gt;10 ft). Plain films + CT if positive or equivocal.</div>';

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:16px 0 6px;">Pediatric shock — signs</h5>';
    html += '<div style="padding:10px;background:#fee2e2;border-radius:6px;font-size:12px;color:#991b1b;">Children compensate well — <strong>hypotension is a late finding</strong>. Early signs: tachycardia, cool extremities, weak peripheral pulses, prolonged cap refill (&gt;3 sec), narrowed pulse pressure, altered mentation. Minimum SBP = 70 + (2 × age in years) for ages 1-10.</div>';

    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:16px 0 6px;">Secondary survey — AMPLE + head-to-toe</h5>';
    html += '<div style="padding:10px;background:var(--g50);border-radius:6px;font-size:12px;"><strong>AMPLE:</strong> Allergies, Medications, Past history, Last meal, Events of injury. Head-to-toe exam; log-roll for back; digital rectal; neurovascular checks of all extremities.</div>';

    html += S.ref('ATLS 10th ed; PALS 2020; PECARN c-spine rule; CRASH-2 trial (TXA).');
    el.innerHTML = html;
  }
})();

// ============================================================
// APGAR SCORE (inside Neonatal)
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-apgar-calc' || e.target.closest('#btn-apgar-calc')) calcApgar();
  });
  function calcApgar() {
    var keys = ['appearance','pulse','grimace','activity','respiration'];
    var total = keys.reduce(function(s, k) {
      return s + (parseInt(document.getElementById('apgar-' + k).value) || 0);
    }, 0);
    var el = document.getElementById('apgar-result');
    var color, severity, guidance;
    if (total >= 7) {
      color = '#10b981'; severity = 'Reassuring';
      guidance = 'Routine newborn care. Continue reassessment. Repeat at 5 min.';
    } else if (total >= 4) {
      color = '#f59e0b'; severity = 'Moderately depressed';
      guidance = 'Stimulate, clear airway, warm. Give O2 if cyanotic. Ventilate with PPV if HR &lt;100 or apneic/gasping. Reassess q30 sec.';
    } else {
      color = '#ef4444'; severity = 'Severely depressed';
      guidance = 'Full NRP pathway — PPV immediately. Intubate if PPV ineffective. Chest compressions if HR &lt;60. Epinephrine and volume per NRP.';
    }
    var html = '<div style="padding:10px 14px;border-radius:8px;background:' + color + '10;border:1.5px solid ' + color + ';">';
    html += '<strong style="color:' + color + ';font-size:16px;">Apgar: ' + total + '/10 — ' + severity + '</strong>';
    html += '<div style="font-size:12px;color:var(--g700);margin-top:6px;line-height:1.5;">' + guidance + '</div></div>';
    html += '<p style="font-size:11px;color:var(--g400);margin-top:8px;font-style:italic;">Apgar is a description of status — <strong>never</strong> delay resuscitation while scoring. Follow NRP algorithm based on HR and breathing. Apgar &lt;7 at 5 min: repeat q5 min up to 20 min.</p>';
    el.innerHTML = html;
  }
})();

// ============================================================
// O2 & VENTILATION (teaching reference)
// ============================================================
(function() {
  document.addEventListener('click', function(e) {
    if (e.target.id === 'btn-vent-show' || e.target.closest('#btn-vent-show')) showVent();
  });

  function showVent() {
    var wt = parseFloat(document.getElementById('vent-weight').value);
    var age = parseFloat(document.getElementById('vent-age').value);
    var el = document.getElementById('vent-result');
    var S = window._EM;
    var html = '';

    // ── Target SpO2 quick reference ──
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:0 0 6px;">Target SpO2</h5>';
    html += '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;margin-bottom:14px;"><table style="width:100%;min-width:460px;border-collapse:collapse;font-size:12px;">';
    html += '<thead><tr style="background:var(--g100);"><th style="text-align:left;padding:5px 8px;">Patient</th><th style="text-align:left;padding:5px 8px;">Target</th><th style="text-align:left;padding:5px 8px;">Notes</th></tr></thead><tbody>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Most children</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>94-98%</strong></td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Normal</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Bronchiolitis (AAP 2014/2023)</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>≥90%</strong></td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Don\'t chase higher saturations</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Chronic lung disease / CF</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>90-94%</strong></td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Avoid hyperoxia in CO2 retainers</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Preterm neonate</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>90-95%</strong></td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Minimize ROP risk</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Term neonate (min of life)</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>Per NRP ladder</strong></td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">1 min 60-65%, 10 min 85-95%</td></tr>';
    html += '</tbody></table></div>';

    // ── Escalation ladder ──
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Escalation ladder (step up when target not reached / work of breathing)</h5>';
    html += S.stepBox('#10b981',
      '1. Nasal cannula (low-flow)',
      '<strong>0.5-6 L/min</strong> &nbsp;·&nbsp; FiO2 ~24-40% (rough: room air 21% + 4% per L/min) &nbsp;·&nbsp; comfortable, no humidification needed. Good for mild hypoxia or baseline support.');
    html += S.stepBox('#3b82f6',
      '2. Simple face mask',
      '<strong>6-10 L/min</strong> &nbsp;·&nbsp; FiO2 35-60%. Must keep flow &gt;6 L/min to flush CO2. Tolerated less well than NC.');
    html += S.stepBox('#8b5cf6',
      '3. Non-rebreather mask',
      '<strong>10-15 L/min</strong> &nbsp;·&nbsp; FiO2 60-90%. Reservoir bag must stay inflated. For severe hypoxia with intact breathing.');
    html += S.stepBox('#f59e0b',
      '4. High-flow nasal cannula (HFNC)',
      '<strong>' + (wt ? '1-2 L/kg/min = ' + S.d(wt, 1) + '-' + S.d(wt, 2) + ' L/min' : '1-2 L/kg/min') + '</strong> (max ~50-60 L/min adults) &nbsp;·&nbsp; heated + humidified &nbsp;·&nbsp; FiO2 30-100% titratable &nbsp;·&nbsp; generates ~2-5 cmH2O PEEP &nbsp;·&nbsp; works for bronchiolitis, early resp failure. Reassess at 1-2 h — no improvement → step up.');
    html += S.stepBox('#ef4444',
      '5. Non-invasive ventilation (CPAP / BiPAP)',
      '<strong>CPAP</strong> 5-10 cmH2O (pure PEEP) &nbsp;·&nbsp; <strong>BiPAP</strong> IPAP 10-14 / EPAP 5 (adds pressure support) &nbsp;·&nbsp; FiO2 as needed. Needs cooperative patient, intact airway reflexes, no copious secretions. Contraindicated: coma, apnea, unstable hemodynamics, facial trauma.');
    html += S.stepBox('#dc2626',
      '6. Intubate + mechanical ventilation',
      'When NIV fails, airway compromised, apnea, or GCS ≤8. See RSI under the Airway tab for drugs.');

    // ── BVM how-to ──
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Bag-Valve-Mask (BVM)</h5>';
    html += '<div style="padding:10px 12px;background:var(--blue-light);border-radius:6px;font-size:12px;line-height:1.6;">';
    html += '<strong>When:</strong> apnea, bradycardia (HR &lt;60 in neonate; inadequate breathing at any age), during resuscitation.<br>';
    html += '<strong>Rate:</strong> Newborn 40-60 /min &nbsp;·&nbsp; Infant-child 20-30 /min &nbsp;·&nbsp; Adolescent 10-12 /min (1 breath q5-6 sec).<br>';
    html += '<strong>Tidal volume:</strong> 6-8 mL/kg — only enough to see <strong>gentle chest rise</strong>. Avoid over-ventilation (gastric distension, ↓venous return, lung injury).<br>';
    html += '<strong>Technique:</strong> head tilt / jaw thrust, proper mask seal (E-C grip or 2-thumb), squeeze 1 sec, release fully before next breath. Attach O2 at 10-15 L/min + reservoir.<br>';
    html += '<strong>If not ventilating:</strong> MR SOPA — <u>M</u>ask reseal, <u>R</u>eposition airway, <u>S</u>uction mouth+nose, <u>O</u>pen mouth, <u>P</u>ressure ↑, <u>A</u>lternative airway (LMA or ETT).';
    html += '</div>';

    // ── Mechanical vent settings ──
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Mechanical ventilator — starting settings</h5>';
    var rate = age == null ? '' : (age < 0.1 ? '30-40' : age < 1 ? '25-35' : age < 5 ? '20-25' : age < 12 ? '16-20' : '12-16');
    html += '<div style="padding:10px 12px;background:var(--g50);border-radius:6px;font-size:12px;line-height:1.65;">';
    html += '<strong>Mode:</strong> Volume-control (set TV, get pressure) OR Pressure-control (set pressure, get TV). PRVC / SIMV-PS are hybrids. Pick what your unit uses.<br>';
    html += '<strong>Tidal volume:</strong> <strong>' + (wt ? S.d(wt, 6) + '-' + S.d(wt, 8) + ' mL' : '6-8 mL/kg') + '</strong> <span style="color:var(--g500);font-size:11px;">(6-8 mL/kg)</span>. Use lower (4-6 mL/kg) for ARDS.<br>';
    html += '<strong>Rate:</strong> ' + (rate ? rate + ' /min (for age ' + age + ' yr)' : 'Newborn 30-40 · Infant 25-35 · Child 16-20 · Adolescent 12-16') + '.<br>';
    html += '<strong>PEEP:</strong> start <strong>5 cmH2O</strong> (routine). Increase to 8-12+ for refractory hypoxia (ARDS).<br>';
    html += '<strong>FiO2:</strong> start 100%, wean rapidly to lowest that maintains target SpO2 (usually &lt;60%).<br>';
    html += '<strong>I:E ratio:</strong> 1:2 normally. 1:3-4 for obstructive disease (asthma, bronchiolitis) to allow exhalation.<br>';
    html += '<strong>Inspiratory time:</strong> 0.5 s infant &nbsp;·&nbsp; 0.7-1 s child &nbsp;·&nbsp; 1-1.2 s adolescent.<br>';
    html += '<strong>Pressure limits:</strong> keep plateau &lt;30 cmH2O (ideally &lt;28) to avoid barotrauma.';
    html += '</div>';

    // ── Pressure-time waveform ──
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Pressure-time waveform (what the monitor shows)</h5>';
    html += '<div style="padding:10px;background:white;border:1px solid var(--g200);border-radius:8px;margin-bottom:14px;">';
    html += '<svg viewBox="0 0 540 260" xmlns="http://www.w3.org/2000/svg" style="width:100%;max-width:640px;display:block;margin:0 auto;">' +
      // grid lines
      '<line x1="60" y1="60"  x2="500" y2="60"  stroke="#f3f4f6"/>' +
      '<line x1="60" y1="100" x2="500" y2="100" stroke="#f3f4f6"/>' +
      '<line x1="60" y1="140" x2="500" y2="140" stroke="#f3f4f6"/>' +
      '<line x1="60" y1="180" x2="500" y2="180" stroke="#f3f4f6"/>' +
      // axes
      '<line x1="60" y1="220" x2="500" y2="220" stroke="#374151" stroke-width="1.5"/>' +
      '<line x1="60" y1="20"  x2="60"  y2="220" stroke="#374151" stroke-width="1.5"/>' +
      // y-axis tick labels (cmH2O)
      '<text x="55" y="64"  font-size="10" text-anchor="end" fill="#6b7280">30</text>' +
      '<text x="55" y="104" font-size="10" text-anchor="end" fill="#6b7280">20</text>' +
      '<text x="55" y="144" font-size="10" text-anchor="end" fill="#6b7280">10</text>' +
      '<text x="55" y="184" font-size="10" text-anchor="end" fill="#6b7280">5</text>' +
      '<text x="55" y="224" font-size="10" text-anchor="end" fill="#6b7280">0</text>' +
      // axis titles
      '<text x="275" y="250" font-size="11" text-anchor="middle" fill="#374151">Time (seconds)</text>' +
      '<text x="18" y="120" font-size="11" text-anchor="middle" fill="#374151" transform="rotate(-90 18 120)">Pressure (cmH₂O)</text>' +
      // x-axis time markers
      '<text x="60"  y="238" font-size="10" text-anchor="middle" fill="#6b7280">0</text>' +
      '<text x="200" y="238" font-size="10" text-anchor="middle" fill="#6b7280">2</text>' +
      '<text x="340" y="238" font-size="10" text-anchor="middle" fill="#6b7280">4</text>' +
      '<text x="480" y="238" font-size="10" text-anchor="middle" fill="#6b7280">6</text>' +
      // PEEP reference dashed line (y=180 = 5 cmH2O)
      '<line x1="60" y1="180" x2="500" y2="180" stroke="#10b981" stroke-width="1" stroke-dasharray="4,3" opacity="0.5"/>' +
      // Pressure curve — 3 breaths, each 2s (Ti=0.8s, Te=1.2s); 70px/sec; PEEP=5→y=180, PIP=25→y=80, Plateau=22→y=88
      '<path d="M 60 180 L 80 180 L 90 80 L 145 88 L 155 180 L 200 180 L 210 80 L 265 88 L 275 180 L 340 180 L 350 80 L 405 88 L 415 180 L 480 180" fill="none" stroke="#3b82f6" stroke-width="2.5" stroke-linejoin="round"/>' +
      // PIP label
      '<line x1="120" y1="50" x2="92" y2="78" stroke="#ef4444"/>' +
      '<text x="125" y="48" font-size="11" font-weight="bold" fill="#ef4444">PIP</text>' +
      '<text x="125" y="60" font-size="9" fill="#6b7280">peak inspiratory</text>' +
      // Plateau label
      '<line x1="230" y1="50" x2="145" y2="88" stroke="#a855f7"/>' +
      '<text x="235" y="48" font-size="11" font-weight="bold" fill="#a855f7">Plateau</text>' +
      '<text x="235" y="60" font-size="9" fill="#6b7280">reflects alveolar pressure</text>' +
      // PEEP label
      '<line x1="380" y1="208" x2="345" y2="182" stroke="#10b981"/>' +
      '<text x="385" y="208" font-size="11" font-weight="bold" fill="#10b981">PEEP</text>' +
      // Ti bracket (x=90 to 155)
      '<line x1="90"  y1="32" x2="155" y2="32" stroke="#f59e0b" stroke-width="1"/>' +
      '<line x1="90"  y1="28" x2="90"  y2="36" stroke="#f59e0b"/>' +
      '<line x1="155" y1="28" x2="155" y2="36" stroke="#f59e0b"/>' +
      '<text x="122" y="25" font-size="10" font-weight="bold" text-anchor="middle" fill="#f59e0b">Ti</text>' +
      // Te bracket (x=155 to 200)
      '<line x1="155" y1="202" x2="200" y2="202" stroke="#f59e0b" stroke-width="1"/>' +
      '<line x1="155" y1="198" x2="155" y2="206" stroke="#f59e0b"/>' +
      '<line x1="200" y1="198" x2="200" y2="206" stroke="#f59e0b"/>' +
      '<text x="177" y="215" font-size="10" font-weight="bold" text-anchor="middle" fill="#f59e0b">Te</text>' +
      '</svg>';
    html += '<div style="font-size:11px;color:var(--g500);margin-top:8px;line-height:1.5;"><strong style="color:#ef4444;">PIP</strong> = peak pressure during inspiration (depends on TV, airway resistance, lung compliance). <strong style="color:#a855f7;">Plateau</strong> = static pressure at end-inspiration with brief breath-hold (reflects alveolar pressure — keep &lt;30). <strong style="color:#10b981;">PEEP</strong> = baseline end-expiratory pressure keeping alveoli open. <strong style="color:#f59e0b;">Ti / Te</strong> = inspiratory / expiratory time. Rate &times; (Ti+Te) = 60 s.</div>';
    html += '</div>';

    // ── Troubleshooting: "if this, change that" ──
    html += '<h5 style="font-size:13px;font-weight:700;color:var(--g700);margin:14px 0 6px;">Adjusting for gas exchange</h5>';
    html += '<div style="overflow-x:auto;-webkit-overflow-scrolling:touch;"><table style="width:100%;min-width:480px;border-collapse:collapse;font-size:12px;">';
    html += '<thead><tr style="background:var(--g100);"><th style="text-align:left;padding:5px 8px;">Problem</th><th style="text-align:left;padding:5px 8px;">First lever</th><th style="text-align:left;padding:5px 8px;">Second lever</th></tr></thead><tbody>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>Low SpO2</strong> (oxygenation)</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↑ FiO2</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↑ PEEP (recruits collapsed alveoli)</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>↑ PCO2</strong> (ventilation)</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↑ Rate</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↑ Tidal volume</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>↓ PCO2</strong> (over-ventilating)</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↓ Rate</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↓ Tidal volume</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>High peak pressure</strong></td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Check tube (kink, mucus plug), compliance, bronchospasm</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Suction, bronchodilator, lower TV</td></tr>';
    html += '<tr><td style="padding:5px 8px;border-bottom:1px solid var(--g100);"><strong>Auto-PEEP</strong> (asthma, bronchiolitis)</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">↓ Rate, ↑ expiratory time</td><td style="padding:5px 8px;border-bottom:1px solid var(--g100);">Disconnect + bag briefly if critical</td></tr>';
    html += '</tbody></table></div>';

    // ── Mental model summary ──
    html += '<div style="margin-top:14px;padding:10px 12px;background:#d1fae5;border-radius:6px;font-size:12px;color:#065f46;line-height:1.55;"><strong>Mental model:</strong> Oxygenation is mostly <strong>FiO2 + PEEP</strong>. Ventilation (CO2) is mostly <strong>rate + tidal volume</strong>. Match mode to disease: obstructive (asthma, bronchiolitis) → long expiratory time, permissive hypercapnia. Restrictive (ARDS) → low TV, high PEEP, permissive hypercapnia + hypoxia.</div>';

    html += S.ref('Based on AAP / PALS / AARC guidance. Tailor to individual patient and institutional protocols.');
    el.innerHTML = html;
  }
})();