+
+ | Midazolam (1st-line infusion) |
+ Bolus {f(SEIZURE_DRUGS.midazGttBolus.perKg, SEIZURE_DRUGS.midazGttBolus.max)!.value} mg → gtt {f(SEIZURE_DRUGS.midazGttLow.perKg, SEIZURE_DRUGS.midazGttLow.max, 'mg/hr')!.value}–{f(SEIZURE_DRUGS.midazGttHigh.perKg, SEIZURE_DRUGS.midazGttHigh.max, 'mg/hr')!.value} mg/hr (bolus 0.2 mg/kg, gtt 0.05-0.5 mg/kg/hr) |
+ IV |
+ Titrate to seizure control / burst suppression. |
+
+
+ | Pentobarbital |
+ Bolus {f(SEIZURE_DRUGS.pentobarbBolus.perKg, SEIZURE_DRUGS.pentobarbBolus.max)!.value} mg → gtt {f(SEIZURE_DRUGS.pentobarbGttLow.perKg, null, 'mg/hr')!.value}–{f(SEIZURE_DRUGS.pentobarbGttHigh.perKg, null, 'mg/hr')!.value} mg/hr (bolus 5 mg/kg, gtt 1-5 mg/kg/hr) |
+ IV |
+ Causes hypotension — often need pressors. |
+
+
+ | Propofol |
+ Bolus {f(SEIZURE_DRUGS.propofolBolus.perKg, SEIZURE_DRUGS.propofolBolus.max)!.value} mg → gtt {f(SEIZURE_DRUGS.propofolGttLow.perKg, null, 'mg/hr')!.value}–{f(SEIZURE_DRUGS.propofolGttHigh.perKg, null, 'mg/hr')!.value} mg/hr (bolus 2 mg/kg, gtt 2-5 mg/kg/hr) |
+ IV |
+ PRIS risk in children — limit to <4 mg/kg/hr and duration <48 h. |
+
+
+ | Ketamine |
+ Bolus {f(SEIZURE_DRUGS.ketamineBolus.perKg, SEIZURE_DRUGS.ketamineBolus.max)!.value} mg → gtt {f(SEIZURE_DRUGS.ketamineGttLow.perKg, null, 'mg/hr')!.value}–{f(SEIZURE_DRUGS.ketamineGttHigh.perKg, null, 'mg/hr')!.value} mg/hr (bolus 2 mg/kg, gtt 1-5 mg/kg/hr) |
+ IV |
+ NMDA antagonist — rescue. Good BP profile; useful if refractory to GABAergics. |
+
+
+